Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexander W Justin"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model with stem-like features and stromal surrounds is reported.
Externí odkaz:
https://doaj.org/article/2a6e5c25be114acba644f4ae7b071551
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Funder: WD Armstrong studentship
Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model with stem-like features and s
Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model with stem-like features and s
Autor:
Alexander W Justin, Federico Cammarata, Andrew A Guy, Silas R Estevez, Sebastian Burgess, Hongorzul Davaapil, Agavi Stavropoulou-Tatla, John Ong, Aishwarya G Jacob, Kourosh Saeb-Parsy, Sanjay Sinha, Athina E Markaki
Publikováno v:
Biomaterials Advances. 145:213245
There is a significant need across multiple indications for an off-the-shelf bioengineered tubular graft which fulfils the mechanical and biological requirements for implantation and function but does not necessarily require cells for manufacture or
Publikováno v:
Biotechnology and Bioengineering
Albumin, the most abundant plasma protein in mammals, is a versatile and easily obtainable biomaterial. It is pH and temperature responsive, dissolvable in high concentrations and gels readily in defined conditions. This versatility, together with it
Autor:
John Ong, Junzhe Zhao, Athina E. Markaki, Alexander W. Justin, Galit Katarivas Levy, James M. MacDonald
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Funder: Cambridge Commonwealth, European and International Trust; doi: https://doi.org/10.13039/501100003343
Funder: Trinity College, University of Cambridge; doi: https://doi.org/10.13039/501100000727
Funder: Blavatnik Family Foundation; d
Funder: Trinity College, University of Cambridge; doi: https://doi.org/10.13039/501100000727
Funder: Blavatnik Family Foundation; d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415f546bcc4a7f492009e5794b819341
https://www.repository.cam.ac.uk/handle/1810/307372
https://www.repository.cam.ac.uk/handle/1810/307372
Autor:
Athina E. Markaki, Fotios Sampaziotis, Kourosh Saeb-Parsy, Alexander W. Justin, Ludovic Vallier
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease
The generation of bioengineered biliary tissue could contribute to the management of some of the most impactful cholangiopathies associated with liver transplantation, such as biliary atresia or ischemic cholangiopathy. Recent advances in tissue engi
Publikováno v:
Polymers
Volume 11
Issue 11
Polymers, Vol 11, Iss 11, p 1743 (2019)
Volume 11
Issue 11
Polymers, Vol 11, Iss 11, p 1743 (2019)
Porous coatings on prosthetic implants encourage implant fixation. Enhanced fixation may be achieved using a magneto-active porous coating that can deform elastically in vivo on the application of an external magnetic field, straining in-growing bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978ea795f7ac3a3fa4c33ff59d3c661a
Publikováno v:
IEEE transactions on bio-medical engineering. 67(6)
One of the greatest challenges in fabricating artificial tissues and organs is the incorporation of vascular networks to support the biological requirements of the embedded cells, encouraging tissue formation and maturation. With the advent of 3D pri
Autor:
Ludovic Vallier, Krishnaa T. Mahbubani, Espen Melum, Alexander W. Justin, Si Emma Chen, Olivia C. Tysoe, Hajer Zedira, Teresa Brevini, Athina E. Markaki, Anna Katharina Frank, Kourosh Saeb-Parsy, Fotios Sampaziotis
Publikováno v:
Nature Protocols
Pediatric liver transplantation is often required as a consequence of biliary disorders because of the lack of alternative treatments for repairing or replacing damaged bile ducts. To address the lack of availability of pediatric livers suitable for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a66844d20944107d151c35930937f4c
https://www.repository.cam.ac.uk/handle/1810/293672
https://www.repository.cam.ac.uk/handle/1810/293672
Autor:
Olivia C, Tysoe, Alexander W, Justin, Teresa, Brevini, Si Emma, Chen, Krishnaa T, Mahbubani, Anna K, Frank, Hajer, Zedira, Espen, Melum, Kourosh, Saeb-Parsy, Athina E, Markaki, Ludovic, Vallier, Fotios, Sampaziotis
Publikováno v:
Nature protocols. 14(6)
Pediatric liver transplantation is often required as a consequence of biliary disorders because of the lack of alternative treatments for repairing or replacing damaged bile ducts. To address the lack of availability of pediatric livers suitable for