Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexander W Blocker"'
Publikováno v:
eLife, Vol 5 (2016)
Understanding chromatin function requires knowing the precise location of nucleosomes. MNase-seq methods have been widely applied to characterize nucleosome organization in vivo, but generally lack the accuracy to determine the precise nucleosome pos
Externí odkaz:
https://doaj.org/article/92fa898cff7b42f6ae3a0882679e615a
Autor:
Alyssa Goodman, Alberto Pepe, Alexander W Blocker, Christine L Borgman, Kyle Cranmer, Merce Crosas, Rosanne Di Stefano, Yolanda Gil, Paul Groth, Margaret Hedstrom, David W Hogg, Vinay Kashyap, Ashish Mahabal, Aneta Siemiginowska, Aleksandra Slavkovic
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 4, p e1003542 (2014)
Externí odkaz:
https://doaj.org/article/5244d57974a94c6bbe422ea7c3b0061d
Autor:
Steven L. Scott, Alexander W. Blocker, Fernando V. Bonassi, Hugh A. Chipman, Edward I. George, Robert E. McCulloch
Publikováno v:
Big Data and Information Theory ISBN: 9781003289173
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84882646e78e5ee00c61d41af2ffe8b0
https://doi.org/10.4324/9781003289173-2
https://doi.org/10.4324/9781003289173-2
Autor:
Effie Bruzik, Manway Liu, Amy A. Lee, Joshua Burkart, Richard M. Ransohoff, Swaminathan Mahadevan, Sarel Kobus Jooste, Hongsheng Wang, Raphael Cendrillon, Mariann Polgar-Turcsanyi, Florence Thng, Neda Sattarnezhad, Michael P. Cusack, Glenn Phillips, Ali Shoeb, Tanuja Chitnis, Kashyap Tumkur, Emre Demiralp, David Ben-Shimol, Aaron H. Stoertz, Thomas M. Snyder, Richard A. Rudick, Camilo Diaz-Cruz, Linda C. Norton, Anupam J. Pathak, Tushar A. Parlikar, Philip Stephens, Cindy T Gonzalez, Subhash Tummala, Mark Murphy, Vikram Singh Bajaj, William J. Marks, Nikhil Bikhchandani, Erin Soderberg, Joseph Lehar, Brian C. Healy, Taylor J. Saraceno, Rohit Bakshi, Bonnie I. Glanz, Jane Rhodes, Howard L. Weiner, Alaa Kharbouch, Alexander W. Blocker
Publikováno v:
npj Digital Medicine, Vol 2, Iss 1, Pp 1-8 (2019)
NPJ Digital Medicine
NPJ Digital Medicine
Technological advances in passive digital phenotyping present the opportunity to quantify neurological diseases using new approaches that may complement clinical assessments. Here, we studied multiple sclerosis (MS) as a model neurological disease fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458247ad504f248eb26c291030db5baf
http://link.springer.com/article/10.1038/s41746-019-0197-7
http://link.springer.com/article/10.1038/s41746-019-0197-7
Publikováno v:
Tax Policy and the Economy. 33:131-163
Executive SummaryImplicit government obligations represent the lion’s share of government liabilities in the United States and many other countries. Yet these liabilities are rarely measured, let a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91ae5fb0e7ebde7415c5e81825b31b9
https://doi.org/10.1086/703231
https://doi.org/10.1086/703231
Autor:
Pedram Razavi, Ryan S. Alden, Pasi A. Jänne, Charles M. Rudin, M. Ladanyi, Megan P. Hall, James M. Isbell, Chen Zhao, Kiran Madwani, Byoungsok Jung, Gordon B. Mills, H. Xu, Bob T. Li, Nora Feeney, Alexander W. Blocker, Jorge S. Reis-Filho, Chenlu Hou, David N Brown, G. J. Riely, Filip Janku, Sante Gnerre, Ravi Vijaya Satya, Ronglai Shen, Geoffrey R. Oxnard, Nicholas Eattock, N. Hunkapiller, Yuebi Hu, Cloud P. Paweletz, David B. Solit, Amy J. Sehnert, Alex Aravanis
Publikováno v:
Annals of Oncology. 30:597-603
Background Noninvasive genotyping using plasma cell-free DNA (cfDNA) has the potential to obviate the need for some invasive biopsies in cancer patients while also elucidating disease heterogeneity. We sought to develop an ultra-deep plasma next-gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06499e770a27db39635b47355c863115
https://doi.org/10.1093/annonc/mdz046
https://doi.org/10.1093/annonc/mdz046
Autor:
Steven L. Scott, Alexander W. Blocker, Robert E. McCulloch, Edward I. George, Hugh A. Chipman, Fernando V. Bonassi
Publikováno v:
International Journal of Management Science and Engineering Management. 11:78-88
A useful definition of ‘big data’ is data that is too big to process comfortably on a single machine, either because of processor, memory, or disk bottlenecks. Graphics processing units can allevia...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261584269aefc2f661755d423b2a0317
https://doi.org/10.1080/17509653.2016.1142191
https://doi.org/10.1080/17509653.2016.1142191
We consider the problem of estimating the genome-wide distribution of nucleosome positions from paired-end sequencing data. We develop a modeling approach based on nonparametric templates to control for the variability along the sequence of read coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1999e36e2b0ec016a66140b5186706a