Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alexander W Bird"'
Autor:
Dongqing Pan, Kerstin Klare, Arsen Petrovic, Annika Take, Kai Walstein, Priyanka Singh, Arnaud Rondelet, Alexander W Bird, Andrea Musacchio
Publikováno v:
eLife, Vol 6 (2017)
Centromeres are unique chromosomal loci that promote the assembly of kinetochores, macromolecular complexes that bind spindle microtubules during mitosis. In most organisms, centromeres lack defined genetic features. Rather, they are specified epigen
Externí odkaz:
https://doaj.org/article/a9e0a35e106a4e21ab076ff119ea257d
Autor:
Massimilano Scolz, Per O Widlund, Silvano Piazza, Debora Rosa Bublik, Simone Reber, Leticia Y Peche, Yari Ciani, Nina Hubner, Mayumi Isokane, Martin Monte, Jan Ellenberg, Anthony A Hyman, Claudio Schneider, Alexander W Bird
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51259 (2012)
The regulation of cell migration is a highly complex process that is often compromised when cancer cells become metastatic. The microtubule cytoskeleton is necessary for cell migration, but how microtubules and microtubule-associated proteins regulat
Externí odkaz:
https://doaj.org/article/0195d3dc80a547f481a73955282343ba
Autor:
Marcos Malumbres, Ignacio Pérez de Castro, Marta Cañamero, Anthony Hyman, Alexander W. Bird, Cristina Aguirre-Portolés
PDF file - 224K, Supplemental data includes three figures with a detailed description of the cell cycle characteristics of Tpx2(+/-) cells, quantification of tubulin staining in Tpx2-null embryonic cells and levels of Tpx2 mRNA levels in different ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdb874181bc2c01ffb72bfe50687632
https://doi.org/10.1158/0008-5472.22392243.v1
https://doi.org/10.1158/0008-5472.22392243.v1
Autor:
Alexander W Bird, Anthony A Hyman, Nadine Schmidt, Julian Berlitz, Andrea Ssykor, Ina Poser, Marit Leuschner, Andrei Pozniakovsky, Arnaud Rondelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba01c1a8194207010650334452259d0
https://doi.org/10.15252/rc.2022372128
https://doi.org/10.15252/rc.2022372128
Publikováno v:
Current biology : CB. 31(4)
The precise regulation of microtubule dynamics over time and space in dividing cells is critical for several mitotic mechanisms that ultimately enable cell proliferation, tissue organization, and development. Astral microtubules, which extend from th
The precise execution of mitotic spindle orientation in response to cell shape cues is important for tissue organization and development. The presence of astral microtubules extending from the centrosome towards the cell cortex is essential for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2035e870272dffe3768d9388a019ab6d
https://doi.org/10.1101/2020.05.23.111989
https://doi.org/10.1101/2020.05.23.111989
Autor:
Francesco D. Naso, Italia Anna Asteriti, Giulia Guarguaglini, Alessandro Rosa, Davide Valente, Valentina Palmerini, Marina Mapelli, Divya Singh, Alexander W. Bird, Federica Polverino
Publikováno v:
Current biology 31 (2021): 658–667.e5. doi:10.1016/j.cub.2020.10.096
info:cnr-pdr/source/autori:Polverino F.; Naso F.D.; Asteriti I.A.; Palmerini V.; Singh D.; Valente D.; Bird A.W.; Rosa A.; Mapelli M.; Guarguaglini G./titolo:The Aurora-A%2FTPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability/doi:10.1016%2Fj.cub.2020.10.096/rivista:Current biology/anno:2021/pagina_da:658/pagina_a:667.e5/intervallo_pagine:658–667.e5/volume:31
info:cnr-pdr/source/autori:Polverino F.; Naso F.D.; Asteriti I.A.; Palmerini V.; Singh D.; Valente D.; Bird A.W.; Rosa A.; Mapelli M.; Guarguaglini G./titolo:The Aurora-A%2FTPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability/doi:10.1016%2Fj.cub.2020.10.096/rivista:Current biology/anno:2021/pagina_da:658/pagina_a:667.e5/intervallo_pagine:658–667.e5/volume:31
Mitotic spindle orientation is a crucial process that defines the axis of cell division, contributing to daughter cell positioning and fate, and hence to tissue morphogenesis and homeostasis.1,2 The trimeric NuMA/LGN/Gαi complex, the major determina
Autor:
Gary J. Brouhard, Shweta Bendre, Alexander W. Bird, Conrad Hall, Arnaud Rondelet, Nadine Schmidt, Yu-Chih Lin
Publikováno v:
The Journal of Cell Biology
The microtubule depolymerase MCAK influences chromosomal instability (CIN), but what controls its activity remains unclear. Bendre et al. show that GTSE1, a protein found overexpressed in tumors, regulates microtubule stability and chromosome alignme
Autor:
Alexander W. Bird, Ingrid R. Vetter, Andreas Hecker, Tanja Bange, Franziska Müller, Per O. Widlund, Arnaud Rondelet, Shweta Bendre, Michael Hiller, Nadine Schmidt, Yu-Chih Lin, Divya Singh, Pia Brinkert, Arthur T. Porfetye, Harish C. Thakur
SUMMARYClathrin plays an important role to ensure mitotic spindle stability and efficient chromosome alignment, independently of its well-characterized functions in vesicle trafficking. While clathrin clearly localizes to the mitotic spindle and kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98b3ab898683bc6e1c771a7dd58e918
Autor:
Shweta Bendre, Tanja Bange, Alexander W. Bird, Per O. Widlund, Lisa Mazul, Divya Singh, Arnaud Rondelet, Ingrid R. Vetter, Harish C. Thakur, Andreas Hecker, Franziska Müller, Arthur T. Porfetye, Pia Brinkert, Michael Hiller, Nadine Schmidt, Yu-Chih Lin
Publikováno v:
The Journal of Cell Biology
Clathrin stabilizes microtubules and promotes chromosome alignment during mitosis. Rondelet et al. show that the clathrin–adaptor interaction mechanism is repurposed to recruit GTSE1 to the spindle, which inhibits the microtubule depolymerase MCAK