Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alexander Vang"'
Autor:
Peng Zhang, Denielli Da Silva Goncalves Bos, Alexander Vang, Julia Feord, Danielle J. McCullough, Alexsandra Zimmer, Natalie D'Silva, Richard T. Clements, Gaurav Choudhary
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Reduced exercise capacity in pulmonary hypertension (PH) significantly impacts quality of life. However, the cause of reduced exercise capacity in PH remains unclear. The objective of this study was to investigate whether intrinsic skeletal
Externí odkaz:
https://doaj.org/article/121e8e70e2a144189447e92323cadc38
Autor:
Hamed Babaei, Emilio A. Mendiola, Sunder Neelakantan, Qian Xiang, Alexander Vang, Richard A. F. Dixon, Dipan J. Shah, Peter Vanderslice, Gaurav Choudhary, Reza Avazmohammadi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract In-vivo estimation of mechanical properties of the myocardium is essential for patient-specific diagnosis and prognosis of cardiac disease involving myocardial remodeling, including myocardial infarction and heart failure with preserved ejec
Externí odkaz:
https://doaj.org/article/903096f38e1d4416815576172821f217
Autor:
Xiuna Sun, Erika Nakajima, Carmelissa Norbrun, Parand Sorkhdini, Alina Xiaoyu Yang, Dongqin Yang, Corey E. Ventetuolo, Julie Braza, Alexander Vang, Jason Aliotta, Debasree Banerjee, Mandy Pereira, Grayson Baird, Qing Lu, Elizabeth O. Harrington, Sharon Rounds, Chun Geun Lee, Hongwei Yao, Gaurav Choudhary, James R. Klinger, Yang Zhou
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Chitinase 3 like 1 (CHI3L1) is the prototypic chitinase-like protein mediating inflammation, cell proliferation, and tissue remodeling. Limited data suggest CHI3L1 is elevated in human pulmonary arterial hypertension (PAH) and is associated with dise
Externí odkaz:
https://doaj.org/article/c94d56017b324fc6ab3b4bb678c30de7
Autor:
Alexander Vang, Denielli da Silva Gonçalves Bos, Ana Fernandez-Nicolas, Peng Zhang, Alan R. Morrison, Thomas J. Mancini, Richard T. Clements, Iuliia Polina, Michael W. Cypress, Bong Sook Jhun, Edward Hawrot, Ulrike Mende, Jin O-Uchi, Gaurav Choudhary
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Right ventricular (RV) fibrosis is a key feature of maladaptive RV hypertrophy and dysfunction and is associated with poor outcomes in pulmonary hypertension (PH). However, mechanisms and therapeutic strategies to mitigate RV fibrosis remain unrealiz
Externí odkaz:
https://doaj.org/article/c09c89c74fdf402a92c4c34005193f3d
Autor:
Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, Gaurav Choudhary
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexe
Externí odkaz:
https://doaj.org/article/cba774dd40ca4136a9cc616ff71451f7
Autor:
Emilio A. Mendiola, Denielli da Silva Gonçalves Bos, Dana M. Leichter, Alexander Vang, Peng Zhang, Owen P. Leary, Richard J. Gilbert, Reza Avazmohammadi, Gaurav Choudhary
Publikováno v:
Circulation: Heart Failure.
BACKGROUND: Global indices of right ventricle (RV) function provide limited insights into mechanisms underlying RV remodeling in pulmonary hypertension (PH). While RV myocardial architectural remodeling has been observed in PH, its effect on RV adapt
Autor:
Natalie M. D'Silva, Eric R. Wang, Ana Fernandez‐Nicolas, Alexander Vang, Naohiro Yano, Alexsandra Zimmer, Alexey V. Fedulov, Peng Zhang, Gaurav Choudhary
Publikováno v:
The FASEB Journal. 36
Autor:
Hamed Babaei, Emilio A. Mendiola, Sunder Neelakantan, Qian Xiang, Alexander Vang, Richard A. F. Dixon, Dipan J. Shah, Peter Vanderslice, Gaurav Choudhary, Reza Avazmohammadi
Publikováno v:
Scientific reports. 12(1)
In-vivo estimation of mechanical properties of the myocardium is essential for patient-specific diagnosis and prognosis of cardiac disease involving myocardial remodeling, including myocardial infarction and heart failure with preserved ejection frac
Autor:
Iuliia Polina, Alexander Vang, Edward Hawrot, Denielli da Silva Gonçalves Bos, Thomas Mancini, Peng Zhang, Michael W. Cypress, Richard T. Clements, Ulrike Mende, Alan R. Morrison, Gaurav Choudhary, Ana Fernandez-Nicolas, Jin O-Uchi, Bong Sook Jhun
Publikováno v:
JCI Insight
Right ventricular (RV) fibrosis is a key feature of maladaptive RV hypertrophy and dysfunction and is associated with poor outcomes in pulmonary hypertension (PH). However, mechanisms and therapeutic strategies to mitigate RV fibrosis remain unrealiz
Autor:
Bong Sook Jhun, Michael W. Cypress, Ana Fernandez-Nicolas, Richard T. Clements, Alexander Vang, Jin O-Uchi, Thomas Mancini, Hana Zhou, Gaurav Choudhary
Publikováno v:
The FASEB Journal. 35