Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Alexander Valent"'
Autor:
Frédérique Penault-Llorca, Fabrice Kwiatkowski, Antoine Arnaud, Christelle Levy, Marianne Leheurteur, Lionel Uwer, Olfa Derbel, Annick Le Rol, Jean-Philippe Jacquin, Christelle Jouannaud, Nathalie Quenel-Tueux, Véronique Girre, Cyril Foa, Emmanuel Guardiola, Alain Lortholary, Stéphanie Catala, Séverine Guiu, Alexander Valent, Diane Boinon, Jérome Lemonnier, Suzette Delaloge
Publikováno v:
Breast, Vol 49, Iss , Pp 132-140 (2020)
Purpose: Genomic tests can identify ER-positive HER2-negative localized breast cancer patients who may not benefit from adjuvant chemotherapy. Such tests seem especially interesting in “intermediate” clinico-pathological risk categories. The psyc
Externí odkaz:
https://doaj.org/article/d70246acf83c4620ae1e76cf9395b7f1
Autor:
Daphné Karila, Bruno Donadille, Juliane Léger, Claire Bouvattier, Anne Bachelot, Veronique Kerlan, Sophie Catteau-Jonard, Sylvie Salenave, Frédérique Albarel, Claire Briet, Regis Coutant, Aude Brac De La Perriere, Alexander Valent, Jean-Pierre Siffroi, Sophie Christin-Maitre
Publikováno v:
European Journal of Endocrinology
European Journal of Endocrinology, 2022, pp.EJE-22-0593. ⟨10.1530/EJE-22-0593⟩
European Journal of Endocrinology, 2022, pp.EJE-22-0593. ⟨10.1530/EJE-22-0593⟩
Introduction A gonadectomy is currently recommended in patients with Turner syndrome (TS) and a 45,X/46,XY karyotype, due to a potential risk of gonadoblastoma (GB). However, the quality of evidence behind this recommendation is low. Objective This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59be5415c6121a5574546532deaabe89
https://doi.org/10.1530/eje-22-0593
https://doi.org/10.1530/eje-22-0593
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Data 1. This supplementary data comprises a step-by-step description on how our gene-expression based classification models were generated and validated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775a6802982592c68b0660667a5e03e7
https://doi.org/10.1158/1078-0432.22455450.v1
https://doi.org/10.1158/1078-0432.22455450.v1
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Figure 1. Highlights the EFS and OS for the cohort of neuroblastoma patients with MYCN-amplified disease (n=114, Fig 1a) and for th subcohort of patients >18 months of age with stage 4, MYCN non-amplified disease (n=102, fig. 1b). F, fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c228f0350bfef9c250b0ac38eb3771c9
https://doi.org/10.1158/1078-0432.22455444
https://doi.org/10.1158/1078-0432.22455444
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Purpose: To optimize neuroblastoma treatment stratification, we aimed at developing a novel risk estimation system by integrating gene expression–based classification and established prognostic markers.Experimental Design: Gene expression profiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca2b97b271ac1b8d0f69094ec95fac3
https://doi.org/10.1158/1078-0432.c.6523032
https://doi.org/10.1158/1078-0432.c.6523032
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Table 1. Clinical co-variates for the 709 patients who participated in the study. This supplementary table comprises detailed information on clinical co-variates for all 709 neuroblastoma patients who participated in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36153a937748ade2c45687cdfbb21a46
https://doi.org/10.1158/1078-0432.22455441
https://doi.org/10.1158/1078-0432.22455441
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Table 2. External performance validation of the top five classifiers. This supplementary table comprises the external performance metrics of the top five classifiers. Indicated are the values for classification accuracy, sensitivity , s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14843685e084ad1f63fc9e206b7f0fe1
https://doi.org/10.1158/1078-0432.22455438.v1
https://doi.org/10.1158/1078-0432.22455438.v1
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Table 4. Transcripts that contribute to the SVM_th10 classifier. This supplementary table highlights the transcripts that constitute the SVM_th10 classifier. Indicated for each feature are the Oligo-ID, the Gene symbols, the Entrez gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3154b4da0a902e14ed5e7efd16d71ed7
https://doi.org/10.1158/1078-0432.22455432
https://doi.org/10.1158/1078-0432.22455432
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Legends to Supplementaries. This documents comprises the legends to the supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8889226c2fd7d4c21a33b67d5117ad
https://doi.org/10.1158/1078-0432.22455453
https://doi.org/10.1158/1078-0432.22455453
Autor:
Matthias Fischer, Benedikt Brors, Frank Westermann, Frank Berthold, Jessica Theissen, Thorsten Simon, Roland Eils, Manfred Schwab, Chunxuan Shao, Monika Ortmann, Richard G. Grundy, Isaac Yaniv, Smadar Avigad, Alexander Valent, Jean Bénard, Marta Piqueras, Rosa Noguera, Frank Speleman, Jo Vandesompele, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey, Gian Paolo Tonini, Paola Scaruffi, Akira Nakagawara, Miki Ohira, Robert Seeger, Shahab Asgharzadeh, Anne Engesser, Yvonne Kahlert, Andreas Faldum, Rene Schmidt, Carolina Sterz, Ruth Volland, Barbara Hero, Dilafruz Juraeva, André Oberthuer
Supplementary Data 2. This supplementary data comprises the r-algorithm scripts required to perform the both model selection and validation as described in the step-by-step protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acf7afd97b71e73dc73f5d55b06605c
https://doi.org/10.1158/1078-0432.22455447.v1
https://doi.org/10.1158/1078-0432.22455447.v1