Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Alexander V. Spirov"'
Autor:
Alexander V. Spirov
Publikováno v:
Слово.ру: балтийский акцент, Vol 15, Iss 4, Pp 25-40 (2024)
It is known that almost all hereditary information about the innumerable characteristics of a multicellular organism, including the human body, is encoded in a certain way in the nucleus of a fertilized egg. The principles of the unfolding of genetic
Externí odkaz:
https://doaj.org/article/b8c6e2a3cc294fd09a9f98c6bd8698c6
Publikováno v:
ICT Express, Vol 5, Iss 3, Pp 182-186 (2019)
Understanding of gene regulation mechanisms is one of the main goals in systems biology of development. In this communication we introduce a biologically oriented approach to model gene regulation by explicitly involving all the available empirical d
Externí odkaz:
https://doaj.org/article/50e3c0533b9f43a9a874bb0c54e60f3b
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Gene recruitment or cooption occurs when a gene, which may be part of an existing gene regulatory network (GRN), comes under the control of a new regulatory system. Such re-arrangement of pre-existing networks is likely more common for increasing gen
Externí odkaz:
https://doaj.org/article/8ef9fedf2e5943e79765638782755cd1
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0260497 (2022)
Evolutionary computing (EC) is an area of computer sciences and applied mathematics covering heuristic optimization algorithms inspired by evolution in Nature. EC extensively study all the variety of methods which were originally based on the princip
Externí odkaz:
https://doaj.org/article/f7ca8e83a6564e1b87fb33d1b3206ae0
Autor:
Alex Shlemov, Theodore Alexandrov, Nina Golyandina, David Holloway, Stefan Baumgartner, Alexander V Spirov
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0244701 (2021)
The Bicoid (Bcd) protein is a primary determinant of early anterior-posterior (AP) axis specification in Drosophila embryogenesis. This morphogen is spatially distributed in an anterior-high gradient, and affects particular AP cell fates in a concent
Externí odkaz:
https://doaj.org/article/19a9d0747ae54766bedd4ce8cabac977
Autor:
T. N. Pogorelova, Nevin Ilhan, R. A. Saad, O. P. Gorshkova, Göknur Aktay, B. Kaymaz, Denis B. Tikhonov, T. V. Grishina, E. A. Abdel-Hady, G. T. Ivanova, A. M. Lunichkin, Natalya P. Prutskova, Alexander V. Spirov, I. A. Alliluev, E. N. Chuyan, A. Berk, G. I. Lobov, I. A. Kapustyanov, I. P. Grigorev, M. A. Sabirov, M. I. Zhukovskaya, Patricia Hernández-Cortés, M. A. Ryazanova, Songül Ünüvar, I. S. Mironyuk, I. M. Fedorova, V. F. Levchenko, M. Yu. Ravaeva, E. V. Pushchina, D. E. Korzhevskii, M. Yu. Silkin, A. A. Varaksin, E. V. Shamshurina, B. M. A. El-Kafoury, Elena V. Seliverstova, E. N. Silkina, Yu. A. Silkin, E. G. M. Ismail, A A Nikashina, V. O. Gunko, I. I. Evsyukova, I. V. Cheretaev, V. S. Plekanchuk, Şule Gürsoy
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:424-428
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5c84c0f005d97436f5814e9eec57bb
https://doi.org/10.1134/s0022093021020216
https://doi.org/10.1134/s0022093021020216
Publikováno v:
Biophysics. 66:40-58
Understanding the molecular mechanisms involved in gene regulation is one of the basic issues of systems biology. Conventional approaches to modeling gene regulation often fail to distinguish between the model properties that adequately reflect the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4c74fd32fbe28c9b7049e81f5e87260
https://doi.org/10.1134/s0006350921010073
https://doi.org/10.1134/s0006350921010073
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:1-15
The two related parts of the Conrad Waddington’s proposal, the concepts of canalization and genetic assimilation, formalized yet in the 1940s continue to arouse great interest among professionals, representing one of the most impressive examples of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4658451d995f8b5785e2e002eb9220
https://doi.org/10.1134/s0022093021010014
https://doi.org/10.1134/s0022093021010014
Autor:
Anton V. Eremeev, Alexander V. Spirov
Publikováno v:
Biology Bulletin Reviews. 10:308-323
The basic principles of selectionism were transferred in a simplified form from population genetics to the field of evolutionary computation in order to solve applied problems of optimization and adaptation. Considerable practical experience has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b20ae9de95614a7182566911fe7d8528
https://doi.org/10.1134/s2079086420040076
https://doi.org/10.1134/s2079086420040076
Publikováno v:
2021 17th International Asian School-Seminar "Optimization Problems of Complex Systems (OPCS).
The field of Genetic Algorithms (GA) in modern computer sciences has increasingly become a source of algorithms and methods for the computational systems biology. In this report we extend the definition of the Royal Road functions (specifically, thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaf944a7ff9951c41b7dd5a0699c4c2a
https://doi.org/10.1109/opcs53376.2021.9588730
https://doi.org/10.1109/opcs53376.2021.9588730