Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Alexander V. Kolesnikov"'
Autor:
Henri Leinonen, Jianye Zhang, Laurence M. Occelli, Umair Seemab, Elliot H. Choi, Luis Felipe L.P. Marinho, Janice Querubin, Alexander V. Kolesnikov, Anna Galinska, Katarzyna Kordecka, Thanh Hoang, Dominik Lewandowski, Timothy T. Lee, Elliott E. Einstein, David E. Einstein, Zhiqian Dong, Philip D. Kiser, Seth Blackshaw, Vladimir J. Kefalov, Marcin Tabaka, Andrzej Foik, Simon M. Petersen-Jones, Krzysztof Palczewski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology regardless of the underlying genetic lesion are desirable due to the diversity of mutations
Externí odkaz:
https://doaj.org/article/b5b9cf370c114fd1b6b378a34d01cbf7
Autor:
Marco Bassetto, Alexander V. Kolesnikov, Dominik Lewandowski, Jianying Z. Kiser, Maximilian Halabi, David E. Einstein, Elliot H. Choi, Krzysztof Palczewski, Vladimir J. Kefalov, Philip D. Kiser
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114143- (2024)
Summary: Cellular retinaldehyde-binding protein (CRALBP) supports production of 11-cis-retinaldehyde and its delivery to photoreceptors. It is found in the retinal pigment epithelium (RPE) and Müller glia (MG), but the relative functional importance
Externí odkaz:
https://doaj.org/article/536a6d5ec23043fcb00d03661c34c961
Autor:
Aleksander Tworak, Alexander V. Kolesnikov, John D. Hong, Elliot H. Choi, Jennings C. Luu, Grazyna Palczewska, Zhiqian Dong, Dominik Lewandowski, Matthew J. Brooks, Laura Campello, Anand Swaroop, Philip D. Kiser, Vladimir J. Kefalov, Krzysztof Palczewski
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112982- (2023)
Summary: In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor (RGR) photoisomerase, which is expressed in both the
Externí odkaz:
https://doaj.org/article/d81d281593bd407d80bcbeef11c89b36
Autor:
Amine M. Laradji, Alexander V. Kolesnikov, Bedia B. Karakoçak, Vladimir J. Kefalov, Nathan Ravi
Publikováno v:
ACS Omega, Vol 6, Iss 9, Pp 6172-6184 (2021)
Externí odkaz:
https://doaj.org/article/c342168d384c41428c738f04837cea7f
Publikováno v:
Конденсированные среды и межфазные границы, Vol 23, Iss 2 (2021)
The production technology of hydrometallurgical zinc uses various surfactants to thicken pulps, stabilise the electrolysis process, and obtain high-quality cathode deposits. Numerous researches were conducted to study the cathodic and anodic processe
Externí odkaz:
https://doaj.org/article/86d9a3d0be9c4903adb634728800181f
Autor:
Christina Thebeau, Sheng Zhang, Alexander V. Kolesnikov, Vladimir J. Kefalov, Clay F. Semenkovich, Rithwick Rajagopal
Publikováno v:
Neurobiology of Disease, Vol 137, Iss , Pp 104754- (2020)
Illumination of the retina is a major determinant of energy expenditure by its neurons. However, it remains unclear whether light exposure significantly contributes to the pathophysiology of common retinal disease. Driven by the premise that light ex
Externí odkaz:
https://doaj.org/article/013ba5cee34d4c6785695d78afaea57c
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Efficient chromophore supply is paramount for the continuous function of vertebrate cone photoreceptors. It is well established that isomerization of all-trans- to 11-cis- retinoid in the retinal pigmented epithelium by RPE65 is a key reacti
Externí odkaz:
https://doaj.org/article/9e4f64c14d40407aa7abf37214726453
Autor:
Ignacio Sarria, Yan Cao, Yuchen Wang, Norianne T. Ingram, Cesare Orlandi, Naomi Kamasawa, Alexander V. Kolesnikov, Johan Pahlberg, Vladimir J. Kefalov, Alapakkam P. Sampath, Kirill A. Martemyanov
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3562-3573 (2018)
Summary: Cone photoreceptors scale dynamically the sensitivity of responses to maintain responsiveness across wide range of changes in luminance. Synaptic changes contribute to this adaptation, but how this process is coordinated at the molecular lev
Externí odkaz:
https://doaj.org/article/63f864335a8d4aca8972a86edf45c95c
Publikováno v:
Polymers, Vol 13, Iss 19, p 3324 (2021)
The ocular immune privilege is a phenomenon brought about by anatomical and physiological barriers to shield the eye from immune and inflammation responses. While this phenomenon is beneficial for eyes protection, it is, at the same time, a hindrance
Externí odkaz:
https://doaj.org/article/859a4728a5c84c15ae2fd92000e4d9c6
Autor:
Maria Yu. Zakharova, Arina V. Kozyr, Anna N. Ignatova, Ilya A. Vinnikov, Igor G. Shemyakin, Alexander V. Kolesnikov
Publikováno v:
BioTechniques, Vol 38, Iss 2, Pp 194-198 (2005)
Externí odkaz:
https://doaj.org/article/ebe1b606af214642a6f05160a0b2cafd