Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Alexander V. Chudinov"'
Autor:
Viktoriya E. Kuznetsova, Valeriy E. Shershov, Georgiy F. Shtylev, Ivan Yu. Shishkin, Veronika I. Butvilovskaya, Andrey A. Stomakhin, Irina V. Grechishnikova, Olga A. Zasedateleva, Alexander V. Chudinov
Publikováno v:
Molecules, Vol 29, Iss 19, p 4747 (2024)
A general approach is presented for synthesizing alkyne-modified nucleoside triphosphates via the Sonogashira cross-coupling reaction of unprotected halogenated 2ʹ-deoxynucleoside, followed by monophosphorylation and the reaction of the correspondin
Externí odkaz:
https://doaj.org/article/c0e125fdd8cf492f804da5138bec3fd4
Autor:
Alexander V. Chudinov, Vadim A. Vasiliskov, Viktoriya E. Kuznetsova, Sergey A. Lapa, Natalia A. Kolganova, Edward N. Timofeev
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Replicative strand slippage is a biological phenomenon, ubiquitous among different organisms. However, slippage events are also relevant to non-natural replication models utilizing synthetic polymerase substrates. Strand slippage may notably
Externí odkaz:
https://doaj.org/article/7b73fccda1b24e75804200257fc598d1
Autor:
Elena V. Suprun, Svetlana A. Khmeleva, Gulnaz R. Kutdusova, Konstantin G. Ptitsyn, Viktoriya E. Kuznetsova, Sergey A. Lapa, Alexander V. Chudinov, Sergey P. Radko
Publikováno v:
Electrochemistry Communications, Vol 131, Iss , Pp 107120- (2021)
A set of novel 2′-deoxyuridine-5′-triphosphate (dUTP) derivatives modified with tyrosine (Tyr) or tryptophan (Trp) aromatic groups (m-dUTP) was tested as bearers of electroactive ‘labels’ for double-stranded DNA (dsDNA) detection as well as p
Externí odkaz:
https://doaj.org/article/7349b8f50e914d7e9f75a92d0dd31d10
Autor:
Igor P. Smirnov, Natalia A. Kolganova, Vadim A. Vasiliskov, Alexander V. Chudinov, Edward N. Timofeev
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Non-natural nucleotide substrates are widely used in the enzymatic synthesis of modified DNA. The terminal activity of polymerases in the presence of modified nucleotides is an important, but poorly characterized, aspect of enzymatic DNA syn
Externí odkaz:
https://doaj.org/article/5c05e5230b0b47f886d7827c15df7e11
Autor:
Viktoriya E. Kuznetsova, Valeriy E. Shershov, Teimur O. Guseinov, Rinat A. Miftakhov, Pavel N. Solyev, Roman A. Novikov, Anna I. Levashova, Alexander S. Zasedatelev, Sergey A. Lapa, Alexander V. Chudinov
Publikováno v:
Bioorganic chemistry. 131
New applications of palladium-catalyzed Sonogashira-type cross-coupling reaction between C5-halogenated 2'-deoxycytidine-5'-monophosphate and novel cyanine dyes with a terminal alkyne group have been developed. The present methodology allows to synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ab9dad5f5e0ef748d707a4d95e3ad8
https://pubmed.ncbi.nlm.nih.gov/36528924
https://pubmed.ncbi.nlm.nih.gov/36528924
Publikováno v:
Тонкие химические технологии, Vol 16, Iss 3, Pp 225-231 (2021)
Objectives. The objectives of this work are the development of a multi-primer system based on the polymerase chain reaction (PCR) aimed at the simultaneous detection of six bacterial pathogens that cause human pneumonia and the determination of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1359213308d708c45833af15ce952ba
https://www.finechem-mirea.ru/jour/article/view/1710
https://www.finechem-mirea.ru/jour/article/view/1710
Publikováno v:
Тонкие химические технологии, Vol 16, Iss 2, Pp 148-155 (2021)
Objectives. This study investigated the substrate properties of the modified derivatives of triphosphates of purine and pyrimidine deoxynucleosides (5-propynyl-2’-deoxyuridine-5’-triphosphate, 5-propynyl2’-deoxycytidine-5’-triphosphate, 5-met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd0220c9306918c1d99fa4876252bb9
https://www.finechem-mirea.ru/jour/article/view/1698
https://www.finechem-mirea.ru/jour/article/view/1698
Autor:
Alexander V. Chudinov, Sergey A. Lapa, V. E. Kuznetsova, Yu. V. Moroz, T. V. Nasedkina, A. Yu. Ikonnikova, V. E. Shershov, R. A. Miftakhov, V. A. Vasiliskov
Publikováno v:
Biophysics. 66:25-31
We present a study of the sensitivity of a hybridization microarray analysis of DNA labeled with 2'‑deoxyuridine-5'-triphosphate derivatives that contain the Cy5 and Cy7 cyanine fluorophore dyes. Two Cy5-dUTP and two Cy7-dUTP derivatives that can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e44a30db13993ae889548c084d25a08f
https://doi.org/10.1134/s000635092101005x
https://doi.org/10.1134/s000635092101005x
Autor:
S A Blagodatskikh, V. E. Shershov, Alexander S. Zasedatelev, Sergey A. Lapa, R. A. Miftakhov, E. S. Klochikhina, Alexander V. Chudinov, Yu I Ammur
Publikováno v:
Молекулярная биология. 55:944-955
A prototype of a system for the detection of infectious human pneumonia pathogens based on multiplex solid-phase reverse transcription PCR (RT-PCR) was developed. Primers were designed to identify the DNA of six bacterial pneumonia pathogen strains,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b28d6b675b4ec70331ca06f04d59e4
https://doi.org/10.31857/s0026898421050062
https://doi.org/10.31857/s0026898421050062
Autor:
V. E. Kuznetsova, T. V. Nasedkina, V. A. Vasiliskov, Alexander V. Chudinov, V. E. Shershov, A. Yu. Ikonnikova, Sergey A. Lapa, R. A. Miftakhov
Publikováno v:
Biophysics. 65:736-741
The efficiency of DNA labeling was assessed for 2'-deoxyuridine 5'-triphosphate (dUTP) derivatives containing the Cy7 cyanine dye as a fluorophore. Two fluorescent Cy7-labeled dUTP analogs differed in the chemical structure of the linker between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfd2b20074171b7305918cdd009b14c
https://doi.org/10.1134/s0006350920050188
https://doi.org/10.1134/s0006350920050188