Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Alexander V. Chibalin"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/9735c570ed7741699cf6a202bd10c6bd
Autor:
Anna Nikolaevna Zakharova, Tatiana Alexandrovna Kironenko, Kseniia G. Milovanova, A. A. Orlova, E. Yu Dyakova, G. Kalinnikova Yu, Anastasia V. Kabachkova, Alexander V. Chibalin, Leonid V. Kapilevich
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The effect of treadmill training loads on the content of cytokines in mice skeletal muscles with metabolic disorders induced by a 16 week high fat diet (HFD) was studied. The study included accounting the age and biorhythmological aspects. In the exp
Externí odkaz:
https://doaj.org/article/287648ad1519474980aa45f3ca5b9425
Autor:
Sergej Pirkmajer, Katja Bezjak, Urška Matkovič, Klemen Dolinar, Lake Q. Jiang, Katarina Miš, Katarina Gros, Kseniya Milovanova, Katja Perdan Pirkmajer, Tomaž Marš, Leonid Kapilevich, Alexander V. Chibalin
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The cardiotonic steroids (CTS), such as ouabain and marinobufagenin, are thought to be adrenocortical hormones secreted during exercise and the stress response. The catalytic α-subunit of Na,K-ATPase (NKA) is a CTS receptor, whose largest pool is lo
Externí odkaz:
https://doaj.org/article/f1139225eb304b2e8306b204a9a3e29b
Autor:
Emmani B.M. Nascimento, Louise Mannerås-Holm, Alexander V. Chibalin, Marie Björnholm, Juleen R. Zierath
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 273-282 (2018)
Conversion of diacylglycerol to phosphatidic acid is mediated by diacylglycerol kinases (DGKs), with DGKα specifically linked to adaptive immune responses. We determined the role of DGKα in obesity and inflammatory responses to a high-fat diet (HFD
Externí odkaz:
https://doaj.org/article/af6160f27775468b9fc3787c521c2c23
Autor:
Boubacar Benziane, Melissa L. Borg, Robby Z. Tom, Isabelle Riedl, Julie Massart, Marie Björnholm, Marc Gilbert, Alexander V. Chibalin, Juleen R. Zierath
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 12, Pp 2324-2333 (2017)
Diacylglycerol kinases (DGKs) regulate the balance between diacylglycerol (DAG) and phosphatidic acid. DGKζ is highly abundant in skeletal muscle and induces fiber hypertrophy. We hypothesized that DGKζ influences functional and metabolic adaptatio
Externí odkaz:
https://doaj.org/article/a575ec213d4c468c8904d8f011c9405b
Autor:
Louise Mannerås-Holm, Milena Schönke, Joseph T. Brozinick, Laurène Vetterli, Hai-Hoang Bui, Philip Sanders, Emmani B.M. Nascimento, Marie Björnholm, Alexander V. Chibalin, Juleen R. Zierath
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 907-915 (2017)
Diacylglycerol kinases (DGKs) catalyze the phosphorylation and conversion of diacylglycerol (DAG) into phosphatidic acid. DGK isozymes have unique primary structures, expression patterns, subcellular localizations, regulatory mechanisms, and DAG pref
Externí odkaz:
https://doaj.org/article/2bf3b5d7e0a349b4bf872fc42ccb5f83
Autor:
Metka Petrič, Katarina Mis, Anja Vidović, Alexander V. Chibalin, Sergej Pirkmajer, Klemen Dolinar
Publikováno v:
The Journal of membrane biology. 2021. Vol. 254, № 5/6. P. 531-548
Na+,K+-ATPase (NKA) is essential for maintenance of cellular and whole-body water and ion homeostasis. In the kidney, a major site of ion transport, NKA consumes ~ 50% of ATP, indicating a tight coordination of NKA and energy metabolism. AMP-activate
Autor:
Marie Björnholm, Jonas T. Treebak, Atul S. Deshmukh, Niklas Rye Jørgensen, Christoffer Clemmensen, Anna Krook, Alba Gonzalez-Franquesa, Juleen R. Zierath, Emilie Dalbram, Håkan Karlsson, Stanislava Pankratova, Ben Stocks, Morten Hostrup, Sevda Gheibi, Alexander V. Chibalin, Ankita Agrawal, Thomas Nielsen, Melissa L. Borg, Michael S. Kuefner
Publikováno v:
Gonzalez-Franquesa, A, Stocks, B, Borg, M L, Kuefner, M, Dalbram, E, Nielsen, T S, Agrawal, A, Pankratova, S, Chibalin, A V, Karlsson, H K R, Gheibi, S, Björnholm, M, Jørgensen, N R, Clemmensen, C, Treebak, J T, Hostrup, M, Krook, A, Zierath, J R & Deshmukh, A S 2021, ' Discovery of thymosin β4 as a human exerkine and growth factor ', American Journal of Physiology: Cell Physiology, vol. 321, no. 5, pp. C770-C778 . https://doi.org/10.1152/ajpcell.00263.2021
Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in interorgan cross talk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin β4 (TMSB4
Autor:
Christoph Handschin, Alexander V. Chibalin, Jun Harada, Rasmus J. O. Sjögren, Thomas Moritz, Erik Näslund, Håkan Karlsson, Juleen R. Zierath, Elin Chorell, Shintaro Katayama, Regula Furrer, David Rizo-Roca, Anna Krook
Publikováno v:
Diabetologia
Aims/hypothesisIncreased levels of branched-chain amino acids (BCAAs) are associated with type 2 diabetes pathogenesis. However, most metabolomic studies are limited to an analysis of plasma metabolites under fasting conditions, rather than the dynam
Autor:
Nicolas J, Pillon, Laura, Sardón Puig, Ali, Altıntaş, Prasad G, Kamble, Salvador, Casaní-Galdón, Brendan M, Gabriel, Romain, Barrès, Ana, Conesa, Alexander V, Chibalin, Erik, Näslund, Anna, Krook, Juleen R, Zierath
Publikováno v:
Life science alliance. 6(1)
Obesity and elevated circulating lipids may impair metabolism by disrupting the molecular circadian clock. We tested the hypothesis that lipid overload may interact with the circadian clock and alter the rhythmicity of gene expression through epigeno