Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Alexander V Strunnikov"'
Autor:
Elena M. Pugacheva, Dharmendra Nath Bhatt, Samuel Rivero-Hinojosa, Md Tajmul, Liron Fedida, Emma Price, Yon Ji, Dmitri Loukinov, Alexander V. Strunnikov, Bing Ren, Victor V. Lobanenkov
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-40 (2024)
Abstract Background Pervasive usage of alternative promoters leads to the deregulation of gene expression in carcinogenesis and may drive the emergence of new genes in spermatogenesis. However, little is known regarding the mechanisms underpinning th
Externí odkaz:
https://doaj.org/article/7545d2268ffe4ce8b98c890ee6a96563
Autor:
Elena M Pugacheva, Teruhiko Suzuki, Svetlana D Pack, Natsuki Kosaka-Suzuki, Jeongheon Yoon, Alexander A Vostrov, Eugene Barsov, Alexander V Strunnikov, Herbert C Morse, Dmitri Loukinov, Victor Lobanenkov
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13872 (2010)
BORIS/CTCFL is a paralogue of CTCF, the major epigenetic regulator of vertebrate genomes. BORIS is normally expressed only in germ cells but is aberrantly activated in numerous cancers. While recent studies demonstrated that BORIS is a transcriptiona
Externí odkaz:
https://doaj.org/article/ea03c98b6d9b4c789955d56d6cf365ec
Autor:
Samuel Rivero-Hinojosa, Elena M. Pugacheva, Sungyun Kang, Claudia Fabiola Méndez-Catalá, Alexander L. Kovalchuk, Alexander V. Strunnikov, Dmitri Loukinov, Jeannie T. Lee, Victor V. Lobanenkov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Although CTCF is a well-established 3D chromatin organizer in multicellular eukaryotes, relatively little is known about its male germ cell-specific paralogue, BORIS. Here the authors investigate how CTCF and BORIS interact and compensate in the male
Externí odkaz:
https://doaj.org/article/28f4c6cce58c4b69bfa80168060ded84
Autor:
Abdelhalim Boukaba, Qiongfang Wu, Jian Liu, Cheng Chen, Jierong Liang, Jingjing Li, Alexander V Strunnikov
Publikováno v:
NAR Genomics and Bioinformatics. 4
Separase is a protease that performs critical functions in the maintenance of genetic homeostasis. Among them, the cleavage of the meiotic cohesin during meiosis is a key step in producing gametes in eukaryotes. However, the exact chromosomal localiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c61333fdcded319f6890271c360108
https://doi.org/10.1093/nargab/lqac085
https://doi.org/10.1093/nargab/lqac085
Autor:
Abdelhalim Boukaba, Jian Liu, Carl Ward, Qiongfang Wu, Alexei Arnaoutov, Jierong Liang, Elena M. Pugacheva, Mary Dasso, Victor Lobanenkov, Miguel Esteban, Alexander V. Strunnikov
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Many tumors express meiotic genes that could potentially drive somatic chromosome instability. While germline cohesin subunits SMC1B, STAG3, and REC8 are widely expressed in many cancers, messenger RNA and protein for RAD21L subunit are expressed at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd9634d24df11bf6ce8d11ce325a69f
https://doi.org/10.1073/pnas.2204071119
https://doi.org/10.1073/pnas.2204071119
Autor:
Alexander L. Kovalchuk, Alexander V. Strunnikov, Gabriel E. Zentner, Sungyun Kang, Tajmul, Victor V. Lobanenkov, Naoki Kubo, Dmitri Loukinov, Elena M. Pugacheva, Bing Ren
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The DNA-binding protein CCCTC-binding factor (CTCF) and the cohesin complex function together to establish chromatin loops and regulate gene expression in mammalian cells. It has been proposed that the cohesin complex moving bidirectiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c7c856dfd5298fb4695cb23db7335b
https://doi.org/10.1073/pnas.1911708117
https://doi.org/10.1073/pnas.1911708117
Autor:
Evgeny Teplyakov, Alexander V. Strunnikov, Qiongfang Wu, Elena M. Pugacheva, Abdelhalim Boukaba, Victor V. Lobanenkov, Jian Liu, Dmitry Loukinov
Publikováno v:
Oncotarget
// Evgeny Teplyakov 1,3 , Qiongfang Wu 1 , Jian Liu 1 , Elena M. Pugacheva 2 , Dmitry Loukinov 2 , Abdelhalim Boukaba 1 , Victor Lobanenkov 2 and Alexander Strunnikov 1,3 1 Molecular Epigenetics Laboratory, Guangzhou Institutes of Biomedicine and Hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80a55c293463e66910e6c17e2abd41f
https://doi.org/10.18632/oncotarget.20627
https://doi.org/10.18632/oncotarget.20627
Autor:
Alexander V. Strunnikov, Alexander Samoshkin, Dmitry Loukinov, Jeffrey A. Rosenfeld, Stanimir Dulev
Publikováno v:
Chromosoma. 121:191-199
Condensin complexes are essential for chromosome condensation and segregation in mitosis, while condensin dysfunction, among other pathways leading to chromosomal bridging in mitosis, may play a role in tumor genomic instability, including recently d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04502c44b6ecb11060f916878ae6ca6
https://doi.org/10.1007/s00412-011-0353-6
https://doi.org/10.1007/s00412-011-0353-6
Autor:
Stanimir Dulev, Christelle de Renty, Alexander V. Strunnikov, Etienne Schwob, Rajvi Mehta, Ivan Minkov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2009, 106 (34), pp.14466--71. ⟨10.1073/pnas.0900190106⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2009, 106 (34), pp.14466--71. ⟨10.1073/pnas.0900190106⟩
The CDC14 family of multifunctional evolutionarily conserved phosphatases includes major regulators of mitosis in eukaryotes and of DNA damage response in humans. The CDC14 function is also crucial for accurate chromosome segregation, which is exempl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a486436b1b47cc3ed1971fa298efc52
https://doi.org/10.1073/pnas.0900190106
https://doi.org/10.1073/pnas.0900190106
Publikováno v:
Scopus-Elsevier
SUMO (small ubiquitin-related modifier), a 12 kDa protein with distant similarity to ubiquitin, covalently binds to many proteins in eukaryotic cells. In contrast to ubiquitination, which mainly regulates proteasome-dependent degradation and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c6d31b457b18d6bd24b4916087968e
https://doi.org/10.4161/cc.7.12.6156
https://doi.org/10.4161/cc.7.12.6156