Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Alexander V Lyubimov"'
Autor:
Vanessa C McFadden, Rasha E Shalaby, Saira Iram, Claudia E Oropeza, Jennifer A Landolfi, Alexander V Lyubimov, Mark Maienschein-Cline, Stefan J Green, Klaus H Kaestner, Alan McLachlan
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006239 (2017)
The FoxA family of pioneer transcription factors regulates hepatitis B virus (HBV) transcription, and hence viral replication. Hepatocyte-specific FoxA-deficiency in the HBV transgenic mouse model of chronic infection prevents the transcription of th
Externí odkaz:
https://doaj.org/article/0063c236b7b04b7baaab2a2a676e524c
Autor:
Gerardo M Castillo, Akiko Nishimoto-Ashfield, Cynthia C Jones, Kasim K Kabirov, Alexander Zakharov, Alexander V Lyubimov
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171703 (2017)
We evaluated the mitigating effects of fibroblast growth factor 4 and 7 (FGF4 and FGF7, respectively) in comparison with long acting protected graft copolymer (PGC)-formulated FGF4 and 7 (PF4 and PF7, respectively) administered to C57BL/6J mice a day
Externí odkaz:
https://doaj.org/article/799eeeecf3614442a048e4588dafc4ad
Autor:
Gerardo M. Castillo, Yao Yao, Rebecca E. Guerra, Han Jiang, Akiko Nishimoto-Ashfield, Alexander V. Lyubimov, Joshua F. Alfaro, Kali A. Striker, Nikolay Buynov, Philipp Schwabl, Elijah M. Bolotin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116068- (2024)
Cirrhosis is a liver disease that leads to increased intrahepatic resistance, portal hypertension (PH), and splanchnic hyperemia resulting in ascites, variceal bleeding, and hepatorenal syndrome. Terlipressin, a prodrug that converts to a short half-
Externí odkaz:
https://doaj.org/article/d4444a4a2850450896ee09eee6a97d6e
Autor:
Levin, Irina A. Matveeva, Valentina T. Shashkova, Alexander V. Lyubimov, Galina V. Lyubimova, Liubov S. Koltsova, Andrey I. Shienok, Natalia L. Zaichenko, Peter P.
Publikováno v:
Coatings; Volume 13; Issue 6; Pages: 1071
The luminescent properties of photocured aliphatic and aromatic network polycarbonate methacrylates, containing organic fluorescent dyad, have been studied. The dyad molecule includes two photosensitive fragments—tetraarylimidazole with a hydroxyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::a0d36c8ba58202d670415374077e71be
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figures S2, S3 and S4. Morphometric analysis of laminin-411 β1 chain (S2) and cancer stem cell markers (Notch-1, Notch-3, CD133, Nestin, and c-Myc; S3 and S4) on frozen sections of patient brain tumors. The expression of all markers significantly co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7954ae943f08a0594bc3fcdb183822b6
https://doi.org/10.1158/0008-5472.22423184.v1
https://doi.org/10.1158/0008-5472.22423184.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Video schematically shows the mechanism of glioblastoma treatment by laminin-411 inhibiting nanobioconjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1bcf1d94d457d8f4402664174692d4
https://doi.org/10.1158/0008-5472.22423166.v1
https://doi.org/10.1158/0008-5472.22423166.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figure S5. Binding of the nanobioconjugates to U87MG studied by flow cytometry is inhibited by human soluble TfR. This shows that the chimeric anti-human TfR antibody as part of nanobioconjugate fully retained its activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3255e723448b91bdefabf1741fac2b
https://doi.org/10.1158/0008-5472.22423181
https://doi.org/10.1158/0008-5472.22423181
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figure S10. Expression of Notch-1 and its ligand Jagged1 is significantly decreased in patient-derived glioblastoma cell lines with laminin-411 disruption by CRISPR/Cas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cdcf76995919f58fa3d462d85011ad
https://doi.org/10.1158/0008-5472.22423172.v1
https://doi.org/10.1158/0008-5472.22423172.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figures S8 and S9. Quantification of expression of laminin-411 β1 chain, its binding β1 integrin, Notch family members and other stem cell markers after nanobioconjugate treatment. All markers were significantly suppressed in treated tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c025739000157f1340b145f3c28041b
https://doi.org/10.1158/0008-5472.22423175.v1
https://doi.org/10.1158/0008-5472.22423175.v1
Autor:
Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, Eggehard Holler, Manuel L. Penichet, Tracy R. Daniels-Wells, Lai S. Leoh, Yongmei L. Chen, Alexander V. Lyubimov, Vida Falahatian, Arthur Rekechenetskiy, Zachary B. Grodzinski, Jethro Hu, Jeremy D. Rudnick, Chirag G. Patil, Serguei I. Bannykh, Adam N. Mamelak, Debiao Li, Shawn Wagner, Ekaterina S. Shatalova, Vladimir A. Ljubimov, Frank B. Furnari, Webster K. Cavenee, Alexandra Chesnokova, Hui Ding, Dmytro Klymyshyn, Anna Galstyan, Rameshwar Patil, Tao Sun
Figures S6 and S7. Localization of labeled nanobioconjugates in tumors and biodistribution in brain. The nano drug is seen in the tumor parenchyma outside of blood vessels (S6) and preferentially accumulates in the tumor (peaks at 6 hr post-injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59040ca3ed6482f21e41148d0fe3e603
https://doi.org/10.1158/0008-5472.22423178.v1
https://doi.org/10.1158/0008-5472.22423178.v1