Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexander U Bissell"'
Autor:
Katarina Jojić, Fabio Gherlone, Zoltán Cseresnyés, Alexander U. Bissell, Sandra Hoefgen, Stefan Hoffmann, Ying Huang, Slavica Janevska, Marc Thilo Figge, Vito Valiante
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Sphingofungins are sphinganine analog mycotoxins acting as inhibitors of serine palmitoyl transferases, enzymes responsible for the first step in the sphingolipid biosynthesis. Eukaryotic cells are highly organized with various structures an
Externí odkaz:
https://doaj.org/article/1590b18aa1de4795b6dcabe17f244522
Autor:
Sandra Hoefgen, Alexander U. Bissell, Ying Huang, Fabio Gherlone, Luka Raguž, Christine Beemelmanns, Vito Valiante
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis. Recently, sphingolipid homeostasis has been connected to several human diseases, making serine palmitoyltransferases an interesting therapeutic target. Kn
Externí odkaz:
https://doaj.org/article/a3b04fd7641243648624375f92b171f7
Autor:
Alexander U. Bissell, Julia Rautschek, Sandra Hoefgen, Luka Raguž, Derek J. Mattern, Nauman Saeed, Slavica Janevska, Katarina Jojić, Ying Huang, Johann E. Kufs, Barbara Herboeck, Huijuan Guo, Falk Hillmann, Christine Beemelmanns, Vito Valiante
Publikováno v:
ACS Chem Biol
Sphingofungins belong to a group of structurally related sphingolipid inhibitors produced by fungi, which specifically inhibit serine palmitoyl transferases, enzymes catalyzing the initial step during sphingolipid biosynthesis. Sphingolipids are inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e19c2f19eac7bad1e98affc3aca96a
https://doi.org/10.1021/acschembio.1c00839
https://doi.org/10.1021/acschembio.1c00839
Autor:
Vito Valiante, Sandra Hoefgen, Daniel F.O. Braga, Miriam A. Rosenbaum, Johann E Kufs, Julia Rautschek, Julian Thiele, Alexander U Bissell, Lars Regestein, Jonas Fiedler, Carola Graf
Publikováno v:
ACS synthetic biology. 9(7)
Combinatorial biosynthesis has great potential for designing synthetic circuits and amplifying the production of new active compounds. Studies on multienzyme cascades are extremely useful for improving our knowledge on enzymatic catalysis. In particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e3db721096b8fd98dc524b5fee1ee8
https://pubmed.ncbi.nlm.nih.gov/32525654
https://pubmed.ncbi.nlm.nih.gov/32525654