Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alexander Thielen"'
Autor:
Anna Hake, Anja Germann, Corena de Beer, Alexander Thielen, Martin Däumer, Wolfgang Preiser, Hagen von Briesen, Nico Pfeifer
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1010355 (2023)
The mechanisms triggering the human immunodeficiency virus type I (HIV-1) to switch the coreceptor usage from CCR5 to CXCR4 during the course of infection are not entirely understood. While low CD4+ T cell counts are associated with CXCR4 usage, a pr
Externí odkaz:
https://doaj.org/article/521ceccc7903446593b04194f593778f
Autor:
Verena Dully, Heinrich Balliet, Larissa Frühe, Martin Däumer, Alexander Thielen, Sheena Gallie, Iain Berrill, Thorsten Stoeck
Publikováno v:
Ecological Indicators, Vol 121, Iss , Pp 107049- (2021)
Environmental DNA metabarcoding of benthic bacterial communities emerged as a very powerful technology to assess environmental disturbance effects of coastal salmon aquaculture. A prerequisite for the implementation of this approach into compliance m
Externí odkaz:
https://doaj.org/article/e9da4ef92cda4c0f86d05f41f1570c1c
Autor:
Axel Fun, Thomas Leitner, Linos Vandekerckhove, Martin Däumer, Alexander Thielen, Bernd Buchholz, Andy I. M. Hoepelman, Elizabeth H. Gisolf, Pauline J. Schipper, Annemarie M. J. Wensing, Monique Nijhuis
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Emergence of resistance against integrase inhibitor raltegravir in human immunodeficiency virus type 1 (HIV-1) patients is generally associated with selection of one of three signature mutations: Y143C/R, Q148K/H/R or N155H, repre
Externí odkaz:
https://doaj.org/article/475a8646434341b186207350901f7945
Autor:
Veronica Di Cristanziano, Fedja Farowski, Federica Berrilli, Maristella Santoro, David Di Cave, Christophe Glé, Martin Daeumer, Alexander Thielen, Maike Wirtz, Rolf Kaiser, Kirsten Alexandra Eberhardt, Maria J. G. T. Vehreschild, Rossella D’Alfonso
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1763 (2021)
Background: The human gut microbiota is a microbial ecosystem contributing to the maintenance of host health with functions related to immune and metabolic aspects. Relations between microbiota and enteric pathogens in sub-Saharan Africa are scarcely
Externí odkaz:
https://doaj.org/article/064b6d32cc0f47e0ab4f9fa525f3ae38
Autor:
Danielle P. Porter, Martin Daeumer, Alexander Thielen, Silvia Chang, Ross Martin, Cal Cohen, Michael D. Miller, Kirsten L. White
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6360-6370 (2015)
At Week 96 of the Single-Tablet Regimen (STaR) study, more treatment-naïve subjects that received rilpivirine/emtricitabine/tenofovir DF (RPV/FTC/TDF) developed resistance mutations compared to those treated with efavirenz (EFV)/FTC/TDF by populatio
Externí odkaz:
https://doaj.org/article/c566a42f2e5e40929db4628f4d50f0c5
Autor:
Elizabeth P St John, Birgitte B Simen, Gregory S Turenchalk, Michael S Braverman, Isabella Abbate, Jeroen Aerssens, Olivier Bouchez, Christian Gabriel, Jacques Izopet, Karolin Meixenberger, Francesca Di Giallonardo, Ralph Schlapbach, Roger Paredes, James Sakwa, Gudrun G Schmitz-Agheguian, Alexander Thielen, Martin Victor, Karin J Metzner, Martin P Däumer, HIV-1 Alpha Study Group
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146687 (2016)
Ultra deep sequencing is of increasing use not only in research but also in diagnostics. For implementation of ultra deep sequencing assays in clinical laboratories for routine diagnostics, intra- and inter-laboratory testing are of the utmost import
Externí odkaz:
https://doaj.org/article/a4961bf50e52452a89b38a806cc6e439
Autor:
Christian Pou, Francisco M Codoñer, Alexander Thielen, Rocío Bellido, Susana Pérez-Álvarez, Cecilia Cabrera, Judith Dalmau, Marta Curriu, Yolanda Lie, Marc Noguera-Julian, Jordi Puig, Javier Martínez-Picado, Julià Blanco, Eoin Coakley, Martin Däumer, Bonaventura Clotet, Roger Paredes
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e67085 (2013)
BACKGROUND: Technically, HIV-1 tropism can be evaluated in plasma or peripheral blood mononuclear cells (PBMCs). However, only tropism testing of plasma HIV-1 has been validated as a tool to predict virological response to CCR5 antagonists in clinica
Externí odkaz:
https://doaj.org/article/5168f5f2841948639ec02782a3c6235f
Autor:
Francisco M Codoñer, Christian Pou, Alexander Thielen, Federico García, Rafael Delgado, David Dalmau, Miguel Álvarez-Tejado, Lidia Ruiz, Bonaventura Clotet, Roger Paredes
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19461 (2011)
To explore the potential of deep HIV-1 sequencing for adding clinically relevant information relative to viral population sequencing in heavily pre-treated HIV-1-infected subjects.In a proof-of-concept study, deep sequencing was compared to populatio
Externí odkaz:
https://doaj.org/article/f373af2e98584e9a897433a3fcd76277
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7387 (2009)
The V3 loop of human immunodeficiency virus type 1 (HIV-1) is critical for coreceptor binding and is the main determinant of which of the cellular coreceptors, CCR5 or CXCR4, the virus uses for cell entry. The aim of this study is to provide a large-
Externí odkaz:
https://doaj.org/article/2c2dfe231b734944a268e5dd186bdd57
Autor:
Smaranda Gliga, Nadine Lübke, Alexander Killer, Henning Gruell, Andreas Walker, Alexander T Dilthey, Alexander Thielen, Carolin Lohr, Charlotte Flaßhove, Sarah Krieg, Joanna Ventura Pereira, Tobias Paul Seraphin, Alex Zaufel, Martin Däumer, Hans-Martin Orth, Torsten Feldt, Johannes G Bode, Florian Klein, Jörg Timm, Tom Luedde, Björn-Erik Ole Jensen
Publikováno v:
Clinical Infectious Diseases. 76:408-415
Background Monoclonal antibodies (mAbs) that target severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are predominantly less effective against Omicron variants. Immunocompromised patients often experience prolonged viral shedding, resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d12ee0655d78e54bfc36388bd0ada3f6
https://doi.org/10.1093/cid/ciac802
https://doi.org/10.1093/cid/ciac802