Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Alexander T.H Wu"'
Autor:
Maryam Rachmawati Sumitra, Lung-Ching Chen, Wei-Chen Tsai, Muhamad Ansar, Bashir Lawal, Ntlotlang Mokgautsi, Jih-Hwa Guh, Alexander T.H Wu, Hsu-Shan Huang
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 1, Pp 105423- (2024)
Tetraheterocyclic compounds, derived from natural sources and contemporary pharmaceuticals, have shown promise as multitarget therapeutic agents. However, their mechanisms of action remain partially understood. In this study, we synthesized a series
Externí odkaz:
https://doaj.org/article/47e48b334a9b414aa185b8989a82291c
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4970-4983 (2021)
MAX dimerization (MXD) protein 3 (MXD3) is a member of the MXD family of basic-helix-loop-helix-leucine-zipper (bHLHZ) transcription factors that plays pivotal roles in cell cycle progression and cell proliferation. However, there is insufficient sci
Externí odkaz:
https://doaj.org/article/f23462bf9b9a4c6281e1359d84a1d0ce
Autor:
Tawakaltu Abdulrasheed-Adeleke, Bashir Lawal, Eyuwa Ignatius Agwupuye, Yucheng Kuo, Amarachi Mary Eni, Okwukwe Faith Ekoh, Halimat Yusuf Lukman, Amos S. Onikanni, Femi Olawale, Sani Saidu, Yunusa O. Ibrahim, Maliha Abdullah Saleh Al Ghamdi, Sarah S. Aggad, Abdulrahman A. Alsayegh, Nada H. Aljarba, Gaber El-Saber Batiha, Alexander T.H. Wu, Hsu-Shan Huang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114582- (2023)
In the present study, in vitro, in vivo, and in silico models were used to evaluate the therapeutic potential of Pulmeria alba methanolic (PAm) extract, and we identified the major phytocompound, apigetrin. Our in vitro studies revealed dose-dependen
Externí odkaz:
https://doaj.org/article/c29163d1652040d789e77ef8ea120075
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 5, Pp 104654- (2023)
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-mediated coronavirus disease 2019 (COVID-19) infection remains a global pandemic and health emergency with overwhelming social and economic impacts throughout the world. Therapeutics fo
Externí odkaz:
https://doaj.org/article/5f848e9614c9403c85221381e3d9c557
Autor:
Saidu Sani, Bashir Lawal, Jerius N. Ejeje, Tawakalitu B. Aliu, Amos S. Onikanni, Onwe O. Uchewa, Joy C. Ovoh, Faith U. Ekpa, Chikezie D. Ozoagu, Tochukwu S. Akuma, Success C. Onyeji, Amara Obialor, Saqer S. Alotaibi, Sarah M. Albogami, Michel De Waard, Gaber El-Saber Batiha, Tse Hung Huang, Alexander T.H. Wu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113605- (2022)
The current study evaluated the protective role of Solanum torvum Swartz against diabetes-induced oxidative stress and tissue impairment in streptozotocin (STZ)-intoxicated rats. Rats with STZ (40 mg/kg intraperitoneally (i.p.))-induced diabetes were
Externí odkaz:
https://doaj.org/article/f682671690c3412ab1b07786a3278487
Autor:
Shen-Han Wu, Tsu-Te Yeh, Wei-Chun Hsu, Alexander T.H. Wu, Guoan Li, Chih-Hwa Chen, Chian-Her Lee, Jia-Lin Wu
Publikováno v:
Journal of Orthopaedic Translation, Vol 24, Iss , Pp 144-149 (2020)
Objective: This study hypothesized that the suture anchor of tibial fixation method of PMMR repair technique is the main factor which reduce the gap formation or over displacement of tear site in initial healing, and then investigated the fixation st
Externí odkaz:
https://doaj.org/article/3b961fd96b7c496b85f9f021a58f6237
Autor:
Bashir Lawal, Ching-Yu Lee, Ntlotlang Mokgautsi, Maryam Rachmawati Sumitra, Harshita Khedkar, Alexander T.H. Wu, Hsu-Shan Huang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe application of computational and multi-omics approaches has aided our understanding of carcinogenesis and the development of therapeutic strategies. NSC765598 is a novel small molecule derivative of salicylanilide. This study aims to in
Externí odkaz:
https://doaj.org/article/4e316418df5b40258273fc203b8b814b
Autor:
Ahmed Atef Ahmed Ali, Yu-Ru Lee, Alexander T.H. Wu, Vijesh Kumar Yadav, Dah-Shyong Yu, Hsu-Shan Huang
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 2, Pp 102884- (2021)
As part of our research on developing multi-target small molecule anticancer agents, we designed, synthesized, and biologically evaluated a series of novel diversified analogues based on our thiadiazole-fused anthraquinone lead compound NSC745885. We
Externí odkaz:
https://doaj.org/article/6f55c18cce764f99b9a466da35ba88c0
Autor:
Michael Hsiao, Pei-Jung Lu, Chia-Ning Shen, Jean Lu, Ya-Wen Hsiao, Chien-Hsin Lee, Tsung-Ching Lai, Yu-Cheng Lee, Alexander T.H. Wu, Chi-Tai Yeh, Ming-Shyan Huang, Chih-Jen Yang, Yu-Peng Liu
PDF file - 287K, Cisplatin-induced enrichment of CD133+ cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cff02d179d82d2d71e60791b46fb34
https://doi.org/10.1158/0008-5472.22394742
https://doi.org/10.1158/0008-5472.22394742
Autor:
Michael Hsiao, Pei-Jung Lu, Chia-Ning Shen, Jean Lu, Ya-Wen Hsiao, Chien-Hsin Lee, Tsung-Ching Lai, Yu-Cheng Lee, Alexander T.H. Wu, Chi-Tai Yeh, Ming-Shyan Huang, Chih-Jen Yang, Yu-Peng Liu
PDF file - 289K, Carboplatin induced DNA damage and CD133+ cell enrichment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974a975cfaf05e994092e02e96b83ecb
https://doi.org/10.1158/0008-5472.22394739.v1
https://doi.org/10.1158/0008-5472.22394739.v1