Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Alexander T. H. Wu"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundCancer stem cells (CSCs) have emerged as pivotal players in tumorigenesis, disease progression, and resistance to therapies.ObjectiveThis comprehensive review delves into the intricate relationship between CSCs and the cell-of-origin in div
Externí odkaz:
https://doaj.org/article/8a10a6b28dcc4bffb5094e53088237b0
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2011 (2023)
Tumor angiogenesis and lymphangiogenesis pathways have been identified as important therapeutic targets in non-small cell lung cancer (NSCLC). Bevacizumab, which is a monoclonal antibody, was the initial inhibitor of angiogenesis and lymphangiogenesi
Externí odkaz:
https://doaj.org/article/b1cb7da7b67a44ad8b76a965b87aedc3
Autor:
Chi-Tai Yeh, Tzu-Tao Chen, Pamungkas Bagus Satriyo, Chun-Hua Wang, Alexander T. H. Wu, Tsu-Yi Chao, Kang-Yun Lee, Michael Hsiao, Liang-Shun Wang, Kuang-Tai Kuo
Publikováno v:
Oncogenesis, Vol 10, Iss 7, Pp 1-13 (2021)
Abstract Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are current standard of care for patients with EGFR mutation and metastatic non-small-cell lung carcinoma (NSCLC), but most patients using EGFR TKIs acquire resistance
Externí odkaz:
https://doaj.org/article/06ce9c9834864c0c82dbb26541e4d734
Autor:
Ming-Lang Shih, Bashir Lawal, Sheng-Yao Cheng, Janet O. Olugbodi, Ahmad O Babalghith, Ching-Liang Ho, Simona Cavalu, Gaber El-Saber Batiha, Sarah Albogami, Saqer S. Alotaibi, Jih-Chin Lee, Alexander T. H. Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Papillary thyroid carcinoma (PTC) is the most prevalent endocrine malignancy with a steadily increasing global incidence in recent decades. The pathogenesis of PTC is poorly understood, and the present diagnostic protocols are deficient. Thus, identi
Externí odkaz:
https://doaj.org/article/132447e514394794a600acae034c298a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lung cancer poses a serious threat to human health and has recently been tagged the most common malignant disease with the highest incidence and mortality rate. Although epidermal growth factor (EGFR)-tyrosine kinase inhibitors (TKIs) have significan
Externí odkaz:
https://doaj.org/article/365c620e9ec846b996039d3be9cb6088
Autor:
Kuo-Chang Wen, Pi-Lin Sung, Alexander T. H. Wu, Ping-Chieh Chou, Jun-Hung Lin, Chi-Ying F. Huang, Sai-Ching J. Yeung, Mong-Hong Lee
Publikováno v:
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Ovarian cancer is the leading cause of cancer-related death among women. Complete cytoreductive surgery followed by platinum-taxene chemotherapy has been the gold standard for a long time. Various compounds have been assessed in a
Externí odkaz:
https://doaj.org/article/69004804fc7c4f2db2bf4cc2e4146130
Autor:
Ntlotlang Mokgautsi, Yu-Cheng Kuo, Yan-Jiun Huang, Chien-Hsin Chen, Debabrata Mukhopadhyay, Alexander T. H. Wu, Hsu-Shan Huang
Publikováno v:
Cells, Vol 12, Iss 2, p 266 (2023)
Colorectal cancer (CRC) is one of the most common cancers, and it frequently metastasizes to the liver and lymph nodes. Despite major advances in treatment modalities, CRC remains a poorly characterized biological malignancy, with high reported cases
Externí odkaz:
https://doaj.org/article/9a61204bb5d54058907b3edabbb27900
Autor:
Ntlotlang Mokgautsi, Yu-Cheng Kuo, Chien-Hsin Chen, Yan-Jiun Huang, Alexander T. H. Wu, Hsu-Shan Huang
Publikováno v:
Cells, Vol 12, Iss 2, p 340 (2023)
Colorectal cancer (CRC) is one of the most prevalent malignant tumors, and it contributes to high numbers of deaths globally. Although advances in understanding CRC molecular mechanisms have shed significant light on its pathogenicity, current treatm
Externí odkaz:
https://doaj.org/article/1b912d32059e4380b5201e3eb46e230b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Genetic and environmental factors play important roles in cancer progression, metastasis, and drug resistance. Herein, we used a multiomics data analysis to evaluate the predictive and prognostic roles of genetic and epigenetic modulation of c-MET (h
Externí odkaz:
https://doaj.org/article/681b060fd7b342cbb7e12b6a7b711238
Autor:
Hsin-Ying Lu, Chun-Ming Shih, Shih-Hsien Sung, Alexander T. H. Wu, Tsai-Mu Cheng, Yen-Chung Lin, Chun-Che Shih
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Abdominal aortic aneurysm (AAA) ruptures are unpredictable and lethal. A biomarker predicting AAA rupture risk could help identify patients with small, screen-detected AAAs. Galectin-3 (Gal-3), a β-galactosidase–binding lectin, is involved in infl
Externí odkaz:
https://doaj.org/article/e3da2a1ae78940f7a9d2b1ff43cbdea6