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pro vyhledávání: '"Alexander T Cunha"'
Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development
Publikováno v:
eLife, Vol 13 (2024)
Two major ligand-receptor signaling axes – endothelin Edn3 and its receptor Ednrb, and glial-derived neurotrophic factor (GDNF) and its receptor Ret – are required for migration of enteric nervous system (ENS) progenitors to the hindgut. Mutation
Externí odkaz:
https://doaj.org/article/36c1ef7f71c047d09bcc48d9a22a3835
Autor:
Yi-Tsung Lu, Melissa Plets, Gareth Morrison, Alexander T. Cunha, Steven Y. Cen, Suhn K. Rhie, Kimberly D. Siegmund, Siamak Daneshmand, David I. Quinn, Joshua J. Meeks, Seth P. Lerner, Daniel P. Petrylak, David McConkey, Thomas W. Flaig, Ian M. Thompson, Amir Goldkorn
Publikováno v:
Journal of Clinical Oncology. 40:4506-4506
4506 Background: Neoadjuvant chemotherapy is the standard of care in muscle-invasive bladder cancer patients. However, treatment is intense, the overall benefit is small, and there is no established marker to identify patients who benefit most. The a