Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexander Svanhagen"'
Autor:
Anna Nilsson, Benita Forngren, Sivert Bjurström, Richard J A Goodwin, Elisa Basmaci, Ingela Gustafsson, Anita Annas, Dennis Hellgren, Alexander Svanhagen, Per E Andrén, Johan Lindberg
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47353 (2012)
Drug toxicity observed in animal studies during drug development accounts for the discontinuation of many drug candidates, with the kidney being a major site of tissue damage. Extensive investigations are often required to reveal the mechanisms under
Externí odkaz:
https://doaj.org/article/da12f973b7de43c99eab0949895a5b4a
Autor:
Britt-Marie Swahn, Sveinn Briem, Susanna Eketjäll, Fredrik Jeppsson, Kristina Eliason, Juliette Janson, Alexander Svanhagen, Camilla Niva, Anna-Lena Berg, Sofia Karlström, Karin Kolmodin, Susanne Gustavsson, Johanna Fälting, Ann-Cathrin Radesäter, Paulina Appelkvist
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(24)
Aβ, the product of APP (amyloid precursor protein), has been implicated in the pathophysiology of Alzheimer's disease (AD). β-Site APP cleaving enzyme1 (BACE1) is the enzyme initiating the processing of the APP to Aβ peptides. Small molecule BACE1
Autor:
Johan Bylund, Håkan Andersson, Anita Annas, Dennis Hellgren, Sivert Bjurström, Alexander Svanhagen
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 41(3)
A novel microsomal prostaglandin E synthase 1 (mPGES-1) inhibitor induced kidney injury at exposures representing less than 4 times the anticipated efficacious exposure in man during a 7-day toxicity study in rats. The findings consisted mainly of tu
Autor:
Alexander Svanhagen, Johan Lindberg, Dennis Hellgren, Per E. Andrén, Richard J. A. Goodwin, Sivert Bjurström, Elisa Basmaci, Benita Forngren, Anna Nilsson, Anita Annas, Ingela Gustafsson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e47353 (2012)
PLoS ONE, Vol 7, Iss 10, p e47353 (2012)
Drug toxicity observed in animal studies during drug development accounts for the discontinuation of many drug candidates, with the kidney being a major site of tissue damage. Extensive investigations are often required to reveal the mechanisms under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5396306d73a27c930b349f06dc12f42
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-186048
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-186048
Autor:
Anita Annas, Dennis Hellgren, Johan Bylund, Sievert Bjurström, Benita Forngren, Alexander Svanhagen, Håkan Andersson, Rolf Johansson, Johan Lindberg
Publikováno v:
Toxicology Letters. 211:S114
Autor:
Anita Annas, Anna Nilsson, Alexander Svanhagen, Håkan Andersson, Dennis Hellgren, Per E. Andrén, Sivert Bjurström, Benita Forngren, Johan Lindberg
Publikováno v:
Toxicology Letters. 211:S149