Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alexander Sternberg"'
Autor:
Nicolas Goardon, Emmanouil Nikolousis, Alexander Sternberg, Wai-Kit Chu, Charles Craddock, Peter Richardson, Richard Benson, Mark Drayson, Graham Standen, Paresh Vyas, Sylvie Freeman
Publikováno v:
Haematologica, Vol 94, Iss 8 (2009)
Diagnosis of myelodysplastic syndrome can be difficult especially in cases with a low blast count and a normal karyotype. Flow cytometry has been used to distinguish myelodysplastic syndrome from non-clonal cytopenias. No one single simple flow cytom
Externí odkaz:
https://doaj.org/article/b84f878ca11e46c4a286cf65f1200b6f
Autor:
Kate Cwynarski, Wendy Osborne, Thomas Creasey, Stephen G Jones, Nimish Shah, Nicolas Martinez-Calle, Tobias Menne, Gwyneth Stafford, Pamela McKay, Benjamin J Uttenthal, Sunil Iyengar, Sarah Behan, Alexander Sternberg, Katherine Sturgess, Kirit M. Ardeshna, Deirdre O'Mahony, Andrew McMillan, Graham P. Collins, Sateesh K Nagumantry, George A Follows, Stephen Booth, Anna Santarsieri, John F. Rudge, Pauline Brice
Publikováno v:
Blood. 134:1564-1564
Introduction Since interim results from the EuroNet-PHL-C1 study1were published in 2013 showing that the gonadotoxic drug procarbazine in COPP can be safely replaced with dacarbazine (COPDac) it is increasingly common practice to modify escalated BEA
Autor:
Stephen Mackinnon, Charles Craddock, Sally Killick, Nigel H. Russell, Andrew Peniket, Adam Ivey, Catherine Garnett, Alexander Sternberg, David Grimwade, I-Jun Lau, Paul Virgo, Jessica Doondeea, Paresh Vyas, Andrew Carr, Lynn Quek, Dimitris Karamitros, Batchimeg Usukhbayar, Catherine Porcher, Rosemary E. Gale, Nicolas Goardon, Paul Cahalin, Bilyana Stoilova, Andrew Price, Hannah Hunter, Alison Kennedy, Georg W. Otto, Christopher Allen, Mike Griffiths, Benjamin Davies, Marlen Metzner, Ludovic Lhermitte, Sylvie D. Freeman, Adam J. Mead
Publikováno v:
Quek, L, Otto, G W, Garnett, C, Lhermitte, L, Karamitros, D, Stoilova, B, Lau, I J, Doondeea, J, Doondeea, B, Kennedy, A, Metzner, M, Goardon, N, Ivey, A, Allen, C, Gale, R, Davies, B, Sternberg, A, Killick, S, Hunter, H, Cahalin, P, Price, A, Carr, A, Griffiths, M, Virgo, P, Mackinnon, S, Grimwade, D, Freeman, S, Russell, N, Craddock, C, Mead, A, Peniket, A, Porcher, C & Vyas, P 2016, ' Genetically distinct leukemic stem cells in human CD34-acute myeloid leukemia are arrested at a hemopoietic precursor-like stage ', The Journal of experimental medicine, vol. 213, no. 8, pp. 1513-1535 . https://doi.org/10.1084/jem.20151775
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Quek and colleagues identify human leukemic stem cells (LSCs) present in CD34− AML. In-depth characterization of the functional and clonal aspects of CD34− LSCs indicates that most are similar to myeloid precursors.
Our understanding of the
Our understanding of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e9af69842bafde3417e31c4edd8689
https://kclpure.kcl.ac.uk/en/publications/367ee1cf-ad3c-49b2-896b-a44845284182
https://kclpure.kcl.ac.uk/en/publications/367ee1cf-ad3c-49b2-896b-a44845284182
Autor:
Lorna W. Harries, Katy Hanlon, Elizabeth C. Wolstencroft, Alexander Sternberg, Sian Ellard, Graham R. Standen
Publikováno v:
The Journal of Molecular Diagnostics. 9:42-46
Achieving a specific diagnosis of polycythemia vera (PV) and other myeloproliferative disorders (MPDs) is often costly and complex. However, the recent identification of a V617F mutation in the JH2 domain of the JAK2 gene in a high proportion of pati
Autor:
Chin Yang Li, Alexander Sternberg, Ayalew Tefferi, Terra L. Lasho, David P. Steensma, Jonathan S. Caudill
Publikováno v:
British Journal of Haematology. 133:638-641
C-terminal somatic mutations in nucleophosmin (NPM), a nucleolar shuttling protein that binds p53 and p19(Arf), were recently described in karyotypically normal acute myeloid leukaemia (AML). We analysed primary marrow samples from 150 patients with
Autor:
Riaz Janmohammed, Paresh Vyas, Richard Kaczmarski, Shamit Soneji, Sally Killick, Thomas Seidl, Andrew Carr, Tim Littlewood, Joanne Leach, Claire Chapman, Alexander Sternberg, Andy Peniket, K Clipsham, Edwin Massey, Chris Hatton, Graham R. Standen, Bipin Vadher, Lisa J. Robinson, David G. Bowen
Publikováno v:
Blood. 106:2982-2991
Early, low-risk International Prognostic Scoring System (IPSS) myelodysplastic syndrome (MDS) is a heterogeneous disorder where the molecular and cellular hematopoietic defects are poorly understood. To gain insight into this condition, we analyzed g
Autor:
Paresh Vyas, Derek J. King, Brenda Gibson, Owen P. Smith, Richard L. Stevens, Michael Addison, Momin Ahmed, Alexander Sternberg, Angela Thomas, Irene Roberts, Barbara Stewart, Robert Wynn, Georgina W. Hall, Aengus O'Marcaigh
Publikováno v:
Blood. 103:2480-2489
Acquired mutations in megakaryocyte transcription factor GATA1 have recently been reported in Down syndrome (DS), transient myeloproliferative disorder (TMD), and acute megakaryoblastic leukemia (AMKL). To provide novel insight into GATA1 mutations i
Publikováno v:
British Journal of Haematology. 118:821-824
Osteosclerotic myeloma is a rare disorder characterized by paraproteinaemia and osteosclerosis, and may be associated with a progressive peripheral neuropathy. Patients with widespread osteosclerotic lesions can succumb from neurological complication
Autor:
Gail Jones, Christopher D. Dalley, Jane Parker, Mark Drummond, Alexander Sternberg, David T. Bowen, Paresh Vyas, Emma Das-Gupta, Sally Killick, Juliet Mills, Jonathan Kell, Dominic Culligan, Helen Enright, Kavita Raj, Ghulam J. Mufti, Chris Carter
Publikováno v:
British journal of haematology. 164(4)
Sally B. Killick, Chris Carter, Dominic Culligan, Christopher Dalley, Emma Das-Gupta, Mark Drummond, Helen Enright, Gail L. Jones, Jonathan Kell, Juliet Mills, Ghulam Mufti, Jane Parker, Kavita Raj, Alexander Sternberg, Paresh Vyas, David Bowen and B
Autor:
Saiyed Anwer, Alexander Sternberg
Publikováno v:
Blood. 120(7)