Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexander Somma"'
Autor:
Nisha Holay, Alexander Somma, Mark Duchow, Milad Soleimani, Anna Capasso, Srividya Kottapalli, Joshua Rios, Uma Giri, Jennifer Diamond, Anna Schreiber, Anthony D. Piscopio, Carla Van Den Berg, S. Gail Eckhardt, Todd A. Triplett
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Histone deacetylase inhibitors (HDACi) are currently being explored for the treatment of both solid and hematological malignancies. Although originally thought to exert cytotoxic responses through tumor-intrinsic mechanisms by increasing expression o
Externí odkaz:
https://doaj.org/article/fb11b1e8367b473a9f32db554b699b48
Autor:
Andrew White, Andrew Weinberg, Todd Triplett, Sarah Church, Joshua Rios, Nisha Holay, Alexander Somma, Khrystyna North
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7eb5efe603654268863b2f75cc5043b2
Autor:
Souhil Lebdai, Mathieu Gigoux, Ricardo Alvim, Alexander Somma, Karan Nagar, Abdel Rahmene Azzouzi, Olivier Cussenot, Taha Merghoub, Jedd D. Wolchok, Avigdor Scherz, Kwanghee Kim, Jonathan Coleman
Publikováno v:
OncoImmunology, Vol 8, Iss 6 (2019)
Vascular-targeted photodynamic therapy (VTP) induces rapid destruction of targeted tissues and is a promising therapy for prostate cancer. However, the resulting immune response, which may play an important role in either potentiating or blunting the
Externí odkaz:
https://doaj.org/article/79865f6711d349d98078f002049c7d5a
Autor:
Ricardo G. Alvim, Christopher Hughes, Alexander Somma, Karan K. Nagar, Nathan C. Wong, Stephen La Rosa, Sebastien Monette, Kwanghee Kim, Jonathan A. Coleman
Publikováno v:
Therapeutic Advances in Urology, Vol 11 (2019)
Objective: The objective of this study was to examine the impact of dehydrated human amnion/chorion membrane (dHACM) allografts on prostate and bladder cancer growth in the setting of residual disease and positive surgical margins. Materials and meth
Externí odkaz:
https://doaj.org/article/65024ca5a11a414d8c1292faecf81848
Autor:
Milad Soleimani, Alexander Somma, Tamer Kaoud, Ria Goyal, Jorge Bustamante, Dennis C. Wylie, Nisha Holay, Agnieszka Looney, Uma Giri, Todd Triplett, Kevin Dalby, Jeanne Kowalski, S. Gail Eckhardt, Carla Van Den Berg
Publikováno v:
Molecular Cancer Therapeutics. 21:1547-1560
The heterogeneity and aggressiveness of triple-negative breast cancer (TNBC) contribute to its early recurrence and metastasis. Despite substantial research to identify effective therapeutic targets, TNBC remains elusive in terms of improving patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab09dfa0d80024292cbba0fa5a68d31f
https://doi.org/10.1158/1535-7163.mct-21-1044
https://doi.org/10.1158/1535-7163.mct-21-1044
Autor:
Carla Van Den Berg, S. Gail Eckhardt, Jeanne Kowalski, Kevin Dalby, Todd Triplett, Uma Giri, Agnieszka Looney, Nisha Holay, Dennis C. Wylie, Jorge Bustamante, Ria Goyal, Tamer Kaoud, Alexander Somma, Milad Soleimani
Supplementary Data from Covalent JNK Inhibitor, JNK-IN-8, Suppresses Tumor Growth in Triple-Negative Breast Cancer by Activating TFEB- and TFE3-Mediated Lysosome Biogenesis and Autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217ab67aee498e5b9bb19ce8c2adfe72
https://doi.org/10.1158/1535-7163.22523905
https://doi.org/10.1158/1535-7163.22523905
Autor:
Daniel Osorio, Anna Capasso, S. Gail Eckhardt, Uma Giri, Alexander Somma, Todd M. Pitts, Christopher H. Lieu, Wells A. Messersmith, Stacey M. Bagby, Harinder Singh, Jishnu Das, Nidhi Sahni, S. Stephen Yi, Marieke L. Kuijjer
Single-cell technologies enable high-resolution studies of phenotype-defining molecular mechanisms. However, data sparsity and cellular heterogeneity make modeling biological variability across single-cell samples difficult. We presentSCORPION, a too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::951d20e9d3f950c9e6524642f213e764
https://doi.org/10.1101/2023.01.20.524974
https://doi.org/10.1101/2023.01.20.524974
Autor:
Alexander Somma, Rui Gardner, Jasmine Thomas, Petrina M Georgala, Karan Nagar, Ricardo Alvim, Souhil Lebdai, Steven Zanganeh, Kwanghee Kim, Christopher C.W. Hughes, Lucas Nogueira, Avigdor Scherz, Amelia Riegel, Laura Alvim, Jonathan A. Coleman, Jie Chen, Augusto Barbosa Reis
Publikováno v:
Molecules
Volume 26
Issue 12
Molecules, Vol 26, Iss 3744, p 3744 (2021)
Volume 26
Issue 12
Molecules, Vol 26, Iss 3744, p 3744 (2021)
Purpose: Vascular targeted photodynamic therapy (VTP) is a nonsurgical tumor ablation approach used to treat early-stage prostate cancer and may also be effective for upper tract urothelial cancer (UTUC) based on preclinical data. Toward increasing r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986a189f252c34b4ea4faf15f01b18ef
Autor:
Stephen LaRosa, Alexander Somma, Jonathan A. Coleman, Sylvia Jebiwott, Avigdor Scherz, Renato Santiago Gomez, Kwanghee Kim, Barak Rosenzweig, Katie S. Murray, Renato B. Corradi
Publikováno v:
International Journal of Urology. 26:414-422
OBJECTIVE To investigate the effectiveness of combination treatment of vascular targeted photodynamic therapy and anti-cytotoxic T-lymphocyte-associated antigen 4 immunotherapy in a mouse model of urothelial carcinoma. METHODS We used C57BL/6 mice in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef4bb52b4cb4b936063d6a477225a5d
https://doi.org/10.1111/iju.13878
https://doi.org/10.1111/iju.13878
Autor:
Abdel Rahmene Azzouzi, Kwanghee Kim, Jonathan A. Coleman, Souhil Lebdai, Jedd D. Wolchok, Alexander Somma, Karan Nagar, Ricardo Alvim, Olivier Cussenot, Taha Merghoub, Mathieu Gigoux, Avigdor Scherz
Publikováno v:
OncoImmunology, Vol 8, Iss 6 (2019)
Vascular-targeted photodynamic therapy (VTP) induces rapid destruction of targeted tissues and is a promising therapy for prostate cancer. However, the resulting immune response, which may play an important role in either potentiating or blunting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e00d2b95740fcc76aaeecc8daab980
https://doaj.org/article/79865f6711d349d98078f002049c7d5a
https://doaj.org/article/79865f6711d349d98078f002049c7d5a