Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Alexander Sloutsky"'
Autor:
Ted Cohen, Megan B. Murray, Ibrahim Abubakar, Zibiao Zhang, Alexander Sloutsky, Fernando Arteaga, Katiuska Chalco, Molly F. Franke, Mercedes C. Becerra
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 6, Pp 969-975 (2011)
Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence areas of MDR TB, secondary cases may arise through exposure to MDR TB in the community. To estimate
Externí odkaz:
https://doaj.org/article/43d4d1cf1b724ba18f4fefd4af1b13c3
Autor:
Carole D Mitnick, Molly F Franke, Michael L Rich, Felix A Alcantara Viru, Sasha C Appleton, Sidney S Atwood, Jaime N Bayona, Cesar A Bonilla, Katiuska Chalco, Hamish S F Fraser, Jennifer J Furin, Dalia Guerra, Rocio M Hurtado, Keith Joseph, Karim Llaro, Lorena Mestanza, Joia S Mukherjee, Maribel Muñoz, Eda Palacios, Epifanio Sanchez, Kwonjune J Seung, Sonya S Shin, Alexander Sloutsky, Arielle W Tolman, Mercedes C Becerra
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58664 (2013)
A better understanding of the composition of optimal treatment regimens for multidrug-resistant tuberculosis (MDR-TB) is essential for expanding universal access to effective treatment and for developing new therapies for MDR-TB. Analysis of observat
Externí odkaz:
https://doaj.org/article/12c53c192d8f41c282582520d664c41f
Autor:
Brian Weiner, James Gomez, Thomas C Victor, Robert M Warren, Alexander Sloutsky, Bonnie B Plikaytis, James E Posey, Paul D van Helden, Nicolass C Gey van Pittius, Michael Koehrsen, Peter Sisk, Christian Stolte, Jared White, Sebastien Gagneux, Bruce Birren, Deborah Hung, Megan Murray, James Galagan
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e26038 (2012)
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functi
Externí odkaz:
https://doaj.org/article/9d45c4662e0341f6ad7deca18843397f
Autor:
Megan Murray, Jay Shendure, Shamil R. Sunyaev, Roger Calderon, Dick van Soolingen, Luca Freschi, Thomas R. Ioerger, Devinder Kaur, Bouke C. de Jong, James C. Sacchettini, Maha R. Farhat, Conor J. Meehan, Matthew W. Snyder, Alexander Sloutsky, Leen Rigouts
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Drug resistance diagnostics that rely on the detection of resistance-related mutations could expedite patient care and TB eradication. We perform minimum inhibitory concentration testing for 12 anti-TB drugs together with Illumina whole-genome sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34906c5d52bb43ca945fdc64b9d01451
http://hdl.handle.net/10029/623162
http://hdl.handle.net/10029/623162
Autor:
Devinder Kaur, Carole D. Mitnick, Molly F. Franke, Karen R. Jacobson, Megan Murray, Maha R. Farhat, Alexander Sloutsky
Publikováno v:
Journal of Clinical Microbiology. 54:727-733
Molecular diagnostics that rapidly and accurately predict resistance to fluoroquinolone drugs and especially later-generation agents promise to improve treatment outcomes for patients with multidrug-resistant tuberculosis and prevent the spread of di
Autor:
Natalia Kurepina, Sam Bozeman, Maha R. Farhat, Alexander Sloutsky, James E. Galagan, Elizabeth M. Streicher, Tommie C. Victor, Razvan Sultana, Megan Murray, Karen R. Jacobson, Barry N. Kreiswirth, Hanna Nebenzahl-Guimaraes, Robin M. Warren, Christian Stolte, Dick van Soolingen, Leen Rigouts, James E. Posey, Peter Sisk, Devinder Kaur, Oleg Iartchouk
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 194, 5, pp. 621-30
Europe PubMed Central
American Journal of Respiratory and Critical Care Medicine, 194, 621-30
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
American journal of respiratory and critical care medicine
Europe PubMed Central
American Journal of Respiratory and Critical Care Medicine, 194, 621-30
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
American journal of respiratory and critical care medicine
Item does not contain fulltext RATIONALE: The development of molecular diagnostics that detect both the presence of Mycobacterium tuberculosis in clinical samples and drug resistance-conferring mutations promises to revolutionize patient care and int
Autor:
Leen Rigouts, James C. Sacchettini, Shamil R. Sunyaev, Roger Calderon, Maha R. Farhat, Alexander Sloutsky, Jay Shendure, M. Murray, Luca Freschi, Matthew W. Snyder, Soolingen Dv, Conor J. Meehan, Jong Bd, Devinder Kaur, Thomas R. Ioerger
Drug resistance is threatening attempts at tuberculosis epidemic control. Molecular diagnostics for drug resistance that rely on the detection of resistance-related mutations could expedite patient care and accelerate progress in TB eradication. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2529ab67e0e71ea20fee157d27e2e6d
Autor:
Wilko F.A.R. Verbakel, Suresh Senan, John R. van Sörnsen de Koste, Max Dahele, Alexander Sloutsky, Hassan Mostafavi, Ben J. Slotman
Publikováno v:
Medical Physics. 42:1640-1652
Purpose: (1) To validate retrospective markerless tracking software for small lung tumors by comparing tracked motion in 4-dimensional planning computed tomography (4DCT) derived kV projection images and known tumor motion in the same 4DCT. (2) To ev
Autor:
Molly F. Franke, Karen R. Jacobson, Devinder Kaur, Carole D. Mitnick, Maha R. Farhat, Alexander Sloutsky, Megan Murray
Publikováno v:
The International Journal of Tuberculosis and Lung Disease. 19:339-341
Fluoroquinolone (FQ) drug susceptibility testing (DST) is an important step in the design of effective treatment regimens for multidrug-resistant tuberculosis. Here we compare ciprofloxacin, ofloxacin and moxifloxacin (MFX) resistance results from 22
Autor:
Sebastien Gagneux, Bruce W. Birren, Bhavana Muddukrishna, Robin M. Warren, Jennifer L. Gardy, B. Jesse Shapiro, Eric J. Rubin, Devinder Kaur, Midori Kato-Maeda, Megan Murray, Jamie E. Posey, Natalia Kurepina, Maha R. Farhat, Alistair Calver, Pardis C. Sabeti, Patrick Tang, Bonnie B. Plikaytis, Eric S. Lander, Alexander Sloutsky, Razvan Sultana, Mark L. Borowsky, Elizabeth M. Streicher, Thomas C. Victor, Karen R. Jacobson, Mabel Rodrigues, James C. Johnston, Karen J. Kieser, James E. Galagan, Barry N. Kreiswirth, Marco R. Oggioni
Publikováno v:
Nature genetics
PMC
PMC
M. tuberculosis is evolving antibiotic resistance, threatening attempts at tuberculosis epidemic control. Mechanisms of resistance, including genetic changes favored by selection in resistant isolates, are incompletely understood. Using 116 newly seq