Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexander Sienkiewicz"'
Autor:
Jiang-Ping Wu, Wei-Tong Dong, Chengsheng Chen, Alexander Sienkiewicz, Phouvieng Beyer, Jun Wang, Nizar Haddad, Jon C. Lorenz, Jonathan T. Reeves, Matthew H. Bunner, Nina C. Gonnella, Harald Weinstabl, Géraldine Garavel
Publikováno v:
Organic Process Research & Development. 27:788-797
Autor:
Bikshandarkoil A. Narayanan, Bing-Shiou Yang, Wenjun Tang, Alexander Sienkiewicz, Max Sarvestani, Denis Byrne, Zhibin Li, Laurence J. Nummy, Earl Spinelli, Ashish Chitroda, Nathan K. Yee, Soojin Kim, Shengli Ma, Heewon Lee, Nelu Grinberg, Xudong Wei, Nitinchandra D. Patel, Chris H. Senanayake
Publikováno v:
Organic Process Research & Development. 17:382-389
A facile and economical five-step process for the synthesis of a sodium–hydrogen exchange type I inhibitor (NHE-1) was developed from readily available starting materials in 43% overall yield. Key transformations included a highly efficient copper-
Autor:
Shengli Ma, Jean-Nicolas Desrosiers, Alexander Sienkiewicz, Larry Nummy, Daniel R. Fandrick, Jinhua J. Song, Xudong Wei, Sanjit Sanyal, Heewon Lee, Xingzhong Zeng, Christopher B. Kelly, Chris H. Senanayake, Max Sarvestani, Scot J. Campbell, Nelu Grinberg
Publikováno v:
Organic letters. 16(6)
A scalable de novo synthesis of difluoromethyl pyridines from inexpensive materials is reported. The pyridyl subunit is built around the difluoromethyl group rather than a late stage introduction of this moiety. This user-friendly approach allows acc