Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexander Sheh"'
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Fecal microbiota, live-jslm (RBL; REBYOTA ® ), is the first Food and Drug Administration (FDA)-approved, single-dose, rectally administered, microbiota-based live biotherapeutic product for preventing Clostridioides difficile infection (
Externí odkaz:
https://doaj.org/article/1787f19a72be4f33a0ec043331fd35f3
Autor:
Anthony Mannion, Alexander Sheh, Zeli Shen, JoAnn Dzink-Fox, M. Blanca Piazuelo, Keith T Wilson, Richard Peek, James G. Fox
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTAlong with Helicobacter pylori infection, the gastric microbiota is hypothesized to modulate stomach cancer risk in susceptible individuals. Whole metagenomic shotgun sequencing (WMS) is a sequencing approach to characterize the microbiome wi
Externí odkaz:
https://doaj.org/article/c5c8a7e4aa5f4c73ae508534d0ebb2ef
Autor:
Alexander Sheh, Stephen C. Artim, Monika A. Burns, Jose Arturo Molina-Mora, Mary Anne Lee, JoAnn Dzink-Fox, Sureshkumar Muthupalani, James G. Fox
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Chronic gastrointestinal (GI) diseases are the most common diseases in captive common marmosets. To understand the role of the microbiome in GI diseases, we characterized the gut microbiome of 91 healthy marmosets (303 samples) and 59 marmos
Externí odkaz:
https://doaj.org/article/412799eaa6aa40f8b93ec004ef2d80e0
Autor:
Alexander Sheh, Stephen C. Artim, Monika A. Burns, Jose Arturo Molina-Mora, Mary Anne Lee, JoAnn Dzink-Fox, Sureshkumar Muthupalani, James G. Fox
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Chronic gastrointestinal (GI) diseases are the most common diseases in captive common marmosets (Callithrix jacchus). Despite standardized housing, diet and husbandry, a recently described gastrointestinal syndrome characterized by duodenal
Externí odkaz:
https://doaj.org/article/b347154639da4e02b0bb620ade0a4013
Autor:
Colleen S. McCoy, Anthony J. Mannion, Yan Feng, Carolyn M. Madden, Stephen C. Artim, Gina G. Au, Mikayla Dolan, Jennifer L. Haupt, Monika A. Burns, Alexander Sheh, James G. Fox
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cyclomodulins are virulence factors that modulate cellular differentiation, apoptosis, and proliferation. These include colibactin (pks), cytotoxic necrotizing factor (cnf), and cytolethal distending toxin (cdt). Pathogenic pks+, cnf+, and c
Externí odkaz:
https://doaj.org/article/bb38a18277ca4514935adb7729f9f87d
Autor:
Zeli Shen, JoAnn Dzink-Fox, Yan Feng, Sureshkumar Muthupalani, Anthony J. Mannion, Alexander Sheh, Mark T. Whary, Hilda R. Holcombe, Blanca M. Piazuelo, Luis E. Bravo, Christine Josenhans, Sebastian Suerbaum, Keith T. Wilson, Richard M. Peek, Timothy C. Wang, James G. Fox
Publikováno v:
mSphere, Vol 7, Iss 1 (2022)
ABSTRACT In populations with similar prevalence of Helicobacter pylori infection, cancer risk can vary dramatically. Changes in composition or structure of bacterial communities in the stomach, either at the time of exposure or over the course of H.
Externí odkaz:
https://doaj.org/article/9e55ff19818544809735685cec27b446
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224950 (2019)
The common marmoset (Callithrix jacchus) is increasingly used as an animal model for biomedical research; however, gastrointestinal diseases causing significant morbidity are endemic in many captive marmoset colonies. Establishing gut microbiome patt
Externí odkaz:
https://doaj.org/article/ffdbc9235f734bee9e61147dafc8dfc6
Autor:
Alton G Swennes, Alexander Sheh, Nicola M A Parry, Sureshkumar Muthupalani, Kvin Lertpiriyapong, Alexis García, James G Fox
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106764 (2014)
Farnesoid X receptor (FXR) is a nuclear receptor that regulates bile acid metabolism and transport. Mice lacking expression of FXR (FXR KO) have a high incidence of foci of cellular alterations (FCA) and liver tumors. Here, we report that Helicobacte
Externí odkaz:
https://doaj.org/article/41d5037a4d6b4b26982af47d92c43c0b
Autor:
James G. Fox, Timothy C. Wang, Rebecca C. Fry, Amanda F. McCabe, Melissa W. Mobley, Arkadiusz R. Raczynski, Julia E. Rager, Sureshkumar Muthupalani, Nicola M.A. Parry, Zhongming Ge, Alexander Sheh
PDF file - 48K, Biological functions and canonical pathways associated with both E2 and TAM treatment of infected males and genes associated with function or pathway. A. Diseases and disorders. B. Molecular and Cellular functions. C. Physiological Sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cea4eebb14477442663a5e4269d175
https://doi.org/10.1158/1940-6207.22525637.v1
https://doi.org/10.1158/1940-6207.22525637.v1
Autor:
James G. Fox, Timothy C. Wang, Rebecca C. Fry, Amanda F. McCabe, Melissa W. Mobley, Arkadiusz R. Raczynski, Julia E. Rager, Sureshkumar Muthupalani, Nicola M.A. Parry, Zhongming Ge, Alexander Sheh
Helicobacter pylori infection promotes male predominant gastric adenocarcinoma in humans. Estrogens reduce gastric cancer risk and previous studies showed that prophylactic 17β-estradiol (E2) in INS-GAS mice decreases H. pylori–induced carcinogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066d2e9badf70b84878281f5bb62e960
https://doi.org/10.1158/1940-6207.c.6544841
https://doi.org/10.1158/1940-6207.c.6544841