Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexander S. Zlobin"'
Autor:
Anton V. Malyshev, Vsevolod V. Pavshintcev, Nikita A. Mitkin, Iuliia A. Sukhanova, Vasilina R. Gedzun, Alexander S. Zlobin, Igor I. Doronin, Gennady A. Babkin, Tomi K. Sawyer
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
We employed a structural bioinformatics approach to develop novel peptides with predicted affinity to the binding site for negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGluR5). Primary screening in zebrafish (Danio reri
Externí odkaz:
https://doaj.org/article/76cf2f54874a4026980726e84e360222
Autor:
Nadezhda A. Potapova, Alexander S. Zlobin, Roman N. Perfil’ev, Gennady V. Vasiliev, Elena A. Salina, Yakov A. Tsepilov
Publikováno v:
Plants, Vol 12, Iss 19, p 3490 (2023)
Soybean is a leguminous plant cultivated in many countries and is considered important in the food industry due to the high levels of oil and protein content in the beans. The high demand for soybeans and its products in the industry requires the exp
Externí odkaz:
https://doaj.org/article/2eaa470e190a41229f7f6ea0a404718f
Autor:
Alexander S. Zlobin, Natalia A. Volkova, Natalia A. Zinovieva, Baylar S. Iolchiev, Vugar A. Bagirov, Pavel M. Borodin, Tatiana I. Axenovich, Yakov A. Tsepilov
Publikováno v:
Animals, Vol 13, Iss 1, p 184 (2023)
Negative heterosis can occur on different economically important traits, but the exact biological mechanisms of this phenomenon are still unknown. The present study focuses on determining the genetic factors associated with negative heterosis in inte
Externí odkaz:
https://doaj.org/article/e7b2a57cbcb64451b19e85dbe7bdbfee
Autor:
Anton V. Malyshev, Iuliia A. Sukhanova, Alexander S. Zlobin, Vasilina R. Gedzun, Vsevolod V. Pavshintsev, Ekaterina V. Vasileva, Arthur O. Zalevsky, Igor I. Doronin, Nikita A. Mitkin, Andrey V. Golovin, Maxim L. Lovat, Georgy I. Kovalev, Yurii A. Zolotarev, Askar R. Kuchumov, Gennady A. Babkin, Bernhard Luscher
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The aim of the study was to develop better anxiolytics and antidepressants. We focused on GABAA receptors and the α2δ auxiliary subunit of V-gated Ca2+ channels as putative targets because they are established as mediators of efficacious anxiolytic
Externí odkaz:
https://doaj.org/article/744533a44c374b5489533f40fc433b89
Autor:
Arthur O. Zalevsky, Alexander S. Zlobin, Vasilina R. Gedzun, Roman V. Reshetnikov, Maxim L. Lovat, Anton V. Malyshev, Igor I. Doronin, Gennady A. Babkin, Andrey V. Golovin
Publikováno v:
Molecules, Vol 24, Iss 2, p 277 (2019)
Peptides are promising drug candidates due to high specificity and standout safety. Identification of bioactive peptides de novo using molecular docking is a widely used approach. However, current scoring functions are poorly optimized for peptide li
Externí odkaz:
https://doaj.org/article/0547a369577e40568d69c725d8210959
Autor:
Yakov A. Tsepilov, Baylar S Iolchiev, Pavel S. Nikulin, Tatiana I. Aksenovich, Alexander S. Zlobin, Natalia A Zinovieva, Pavel M. Borodin, Vugar A Bagirov, Natalia A. Volkova
Publikováno v:
Genes
Volume 12
Issue 3
Genes, Vol 12, Iss 367, p 367 (2021)
Volume 12
Issue 3
Genes, Vol 12, Iss 367, p 367 (2021)
Despite their economic value, sheep remain relatively poorly studied animals in terms of the number of known loci and genes associated with commercially important traits. This gap in our knowledge can be filled in by performing new genome-wide associ
Autor:
Marcus Perola, Alexandra S. Shadrina, Caroline Hayward, James F. Wilson, Yurii S. Aulchenko, Sodbo Zh Sharapov, Eugene D Pakhomov, Alexander S. Zlobin, Olga O. Zaytseva, Gordan Lauc, Lucija Klaric, Tõnu Esko, Yakov A. Tsepilov
Publikováno v:
Human molecular genetics. 30(13)
The N-glycosylation of immunoglobulin G (IgG) affects its structure and function. It has been demonstrated that IgG N-glycosylation patterns are inherited as complex quantitative traits. Genome-wide association studies identified loci harboring genes
Autor:
Natalia A. Volkova, Pavel M. Borodin, Alexander S. Zlobin, Yakov A. Tsepilov, Tatiana I. Aksenovich
Publikováno v:
J Anim Sci
Identification of quantitative trait loci (QTL) and candidate genes that affect growth intensity is a prerequisite for the marker-assisted selection for economically important traits. The number of QTL studies on sheep is relatively small in comparis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae78d5cedcf9ee8fcfd516143cf6542
https://europepmc.org/articles/PMC6898489/
https://europepmc.org/articles/PMC6898489/
Autor:
Sergey Vladimirovich Kokhanovsky, Alexey Y. Belyaev, Pavel V. Dudkin, V. G. Krishtop, T. V. Krishtop, D. A. Zhevnenko, Alexander S. Zlobin
Publikováno v:
International Conference on Micro- and Nano-Electronics 2018.
In this paper we demonstrate a new prototype of a high-precision ultra-low-frequency hydrophone on the basis of a planar type electrochemical transducer (ECT). We have developed a new planar electrochemical microchip and have invented a mechanical sy
Autor:
Alexander S, Zlobin, Natalia A, Volkova, Pavel M, Borodin, Tatiana I, Aksenovich, Yakov A, Tsepilov
Publikováno v:
Archives Animal Breeding
Identification of quantitative trait loci (QTLs) and candidate genes that affect growth intensity is a prerequisite for the marker-assisted selection of economically important traits. The number of QTL studies on sheep is relatively small in comparis