Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Alexander S Apt"'
Autor:
Margarita O. Shleeva, Irina A. Linge, Ivan A. Gligonov, Galina N. Vostroknutova, Denis M. Shashin, Andrey M. Tsedilin, Alexander S. Apt, Arseny S. Kaprelyants, Alexander P. Savitsky
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Mycobacterium tuberculosis (Mtb) is able to transition into a dormant state, causing the latent state of tuberculosis. Dormant mycobacteria acquire resistance to all known antibacterial drugs and can survive in the human body for decades bef
Externí odkaz:
https://doaj.org/article/0e905edfdb7b4f9784a8b789e6ede5a3
Autor:
Marina A Kapina, Elvira I Rubakova, Konstantin B Majorov, Nadezhda N Logunova, Alexander S Apt
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72773 (2013)
The balance between activation and inhibition of local immune responses in affected tissues during prolonged chronic infections is important for host protection. There is ample evidence that regulatory, tolerogenic dendritic cells (DC) are developed
Externí odkaz:
https://doaj.org/article/a3dd36ec0e64414fa732b3ecdcd5fc93
Autor:
Marina A Kapina, Galina S Shepelkova, Vadim G Avdeenko, Anna N Guseva, Tatiana K Kondratieva, Vladimir V Evstifeev, Alexander S Apt
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21878 (2011)
IL-11 is multifunctional cytokine whose physiological role in the lungs during pulmonary tuberculosis (TB) is poorly understood. Here, using in vivo administration of specific antibodies against IL-11, we demonstrate for the first time that blocking
Externí odkaz:
https://doaj.org/article/43b759affe9c42c9bf3d4e4e9e183f6d
Autor:
Anastasiia Tsareva, Pavel V. Shelyakin, Irina A. Shagina, Mikhail Yu. Myshkin, Ekaterina M. Merzlyak, Valeriia V. Kriukova, Alexander S. Apt, Irina A. Linge, Dmitriy M. Chudakov, Olga V. Britanova
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mycobacterium tuberculosis (Mtb) remains a major threat worldwide, although only a fraction of infected individuals develops tuberculosis (TB). TB susceptibility is shaped by multiple genetic factors, and we performed comparative immunological analys
Externí odkaz:
https://doaj.org/article/21bbd6e3c48540329f6d1feed125b949
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/71499df9067b45fc8421c486510dff41
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 688 (2023)
The penetration of substances through the bacterial cell envelope is a complex and underinvestigated process. Mitochondria-targeted antioxidant and antibiotic SkQ1 (10-(plastoquinonyl)decyltriphenylphosphonium) is an excellent model for studying the
Externí odkaz:
https://doaj.org/article/64c67f6bb0054bfaaf24e056c36b62c6
Publikováno v:
Bulletin of Experimental Biology and Medicine. 171:445-448
We studied the effectiveness of anti-tuberculosis vaccination with BCG in mice of inbred strains and F1 hybrids (highly resistant to tuberculosis infection) that represent a wide range of genetically determined differences in susceptibility to infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2de557fe0e35ee12d2fe899731166dc
https://doi.org/10.1007/s10517-021-05246-9
https://doi.org/10.1007/s10517-021-05246-9
Autor:
Nikolay E. Nifantiev, Anton P. Tyurin, Alexander S. Shashkov, Andrey V. Mardanov, Evgeny N. Nikolaev, S. S. Terekhov, Valeriya V. Kulyaeva, Eugene A. Rogozhin, Genrikh S. Katrukha, Alexey A. Chistov, Alexander S. Apt, Elena G. Gladkikh, Natalia E. Grammatikova, Ilya A. Osterman, Alexander Zherebker, Konstantin B. Majorov, Nikolai V. Ravin, Olga S. Ostroumova, Zakhar O. Shenkarev, Tatyana V. Kravchenko, Alexander S. Paramonov, Maxim V. Shuvalov, Vladimir A. Brylev, Milita V Kocharovskaya, Dmitry S. Tsvetkov, Elena P. Mirchink, Vladimir A. Korshun, Anna A. Baranova, A. V. Beletsky, Elena B. Isakova, Vera A. Alferova, Olga A. Dontsova, Olda A. Lapchinskaya, Elena V. Svirshchevskaya, Igor A. Prokhorenko, Svetlana S. Efimova, Igor Ivanov, Mikhail V. Biryukov, Gulnara K. Kudryakova
Publikováno v:
Angewandte Chemie International Edition. 60:18694-18703
We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA-Ac-5812. Two major components of the mixture, named gausemycins A and B, were isolated, and their structures were elucidated. The compounds are cyclic peptides wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd842f388c39add9ec81b14210f024f
https://doi.org/10.1002/anie.202104528
https://doi.org/10.1002/anie.202104528
Publikováno v:
Bulletin of Experimental Biology and Medicine. 171:453-457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0aa0e8d15af53aecb69ab62fff2e436
https://doi.org/10.47056/0365-9615-2021-171-4-453-457
https://doi.org/10.47056/0365-9615-2021-171-4-453-457
Autor:
Dmitrii S. Shcherbinin, Olga V. Britanova, Vasiliy N Zubov, Evgeny S. Egorov, Nadezhda Logunova, Jens Meiler, Alexander S. Apt, Mikhail V. Pogorelyy, Alina Pereverzeva, Nina G. Bozhanova, Ekaterina M. Merzlyak, Dmitriy M. Chudakov, Pavel V. Shelyakin, Mikhail Shugay, Valeriia V Kriukova
Publikováno v:
Proc Natl Acad Sci U S A
T cell maturation and activation depend upon T cell receptor (TCR) interactions with a wide variety of antigenic peptides displayed in a given major histocompatibility complex (MHC) context. Complementarity-determining region 3 (CDR3) is the most var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a980c798dcd35593eb94aa7a72a153c1
https://doi.org/10.1073/pnas.2003170117
https://doi.org/10.1073/pnas.2003170117