Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Alexander S, Paramonov"'
Autor:
Barbara Z. Eletskaya, Anton F. Mironov, Ilya V. Fateev, Maria Ya. Berzina, Konstantin V. Antonov, Olga S. Smirnova, Alexandra B. Zatsepina, Alexandra O. Arnautova, Yulia A. Abramchik, Alexander S. Paramonov, Alexey L. Kayushin, Anastasia L. Khandazhinskaya, Elena S. Matyugina, Sergey N. Kochetkov, Anatoly I. Miroshnikov, Igor A. Mikhailopulo, Roman S. Esipov, Irina D. Konstantinova
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 798 (2024)
Enzymatic transglycosylation of the fleximer base 4-(4-aminopyridine-3-yl)-1H-pyrazole using recombinant E. coli purine nucleoside phosphorylase (PNP) resulted in the formation of “non-typical” minor products of the reaction. In addition to “ty
Externí odkaz:
https://doaj.org/article/6dc5ba4973204c2f85cf40e3a5e85b6f
Autor:
Ilya V. Fateev, Sobirdjan A. Sasmakov, Jaloliddin M. Abdurakhmanov, Abdukhakim A. Ziyaev, Shukhrat Sh. Khasanov, Farkhod B. Eshboev, Oybek N. Ashirov, Valeriya D. Frolova, Barbara Z. Eletskaya, Olga S. Smirnova, Maria Ya. Berzina, Alexandra O. Arnautova, Yulia A. Abramchik, Maria A. Kostromina, Alexey L. Kayushin, Konstantin V. Antonov, Alexander S. Paramonov, Valeria L. Andronova, Georgiy A. Galegov, Roman S. Esipov, Shakhnoz S. Azimova, Anatoly I. Miroshnikov, Irina D. Konstantinova
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 745 (2024)
1,2,4-Triazole derivatives have a wide range of biological activities. The most well-known drug that contains 1,2,4-triazole as part of its structure is the nucleoside analogue ribavirin, an antiviral drug. Finding new nucleosides based on 1,2,4-tria
Externí odkaz:
https://doaj.org/article/ebd7c06da9b2400790c2af906ba90ef2
Autor:
Pavel A. Mironov, Alexander S. Paramonov, Olesya V. Reznikova, Victoria N. Safronova, Pavel V. Panteleev, Ilia A. Bolosov, Tatiana V. Ovchinnikova, Zakhar O. Shenkarev
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 332 (2024)
Capitellacin is the β-hairpin membrane-active cationic antimicrobial peptide from the marine polychaeta Capitella teleta. Capitellacin exhibits antibacterial activity, including against drug-resistant strains. To gain insight into the mechanism of c
Externí odkaz:
https://doaj.org/article/4f11ec4017154912a397387fa578ed5e
Autor:
Zakhar O. Shenkarev, Yuri M. Chesnokov, Maxim M. Zaigraev, Anton O. Chugunov, Dmitrii S. Kulbatskii, Milita V. Kocharovskaya, Alexander S. Paramonov, Maxim L. Bychkov, Mikhail A. Shulepko, Dmitry E. Nolde, Roman A. Kamyshinsky, Evgeniy O. Yablokov, Alexey S. Ivanov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The membrane plays a key role in the interaction of non-conventional neurotoxins with the nicotinic receptors.
Externí odkaz:
https://doaj.org/article/54654b9e8be64f4eba0aad318a544d08
Autor:
Maxim L. Bychkov, Aizek B. Isaev, Alexander A. Andreev-Andrievskiy, Konstantin Petrov, Alexander S. Paramonov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14852 (2023)
Alzheimer disease (AD) is a widespread neurodegenerative disease characterized by the accumulation of oligomeric toxic forms of β-amyloid (Aβ1-42) and dysfunction of the cholinergic system in the different brain regions. However, the exact mechanis
Externí odkaz:
https://doaj.org/article/d5af1bfee7fe46589da1141e77d6a539
Autor:
Ekaterina N. Lyukmanova, Pavel A. Mironov, Dmitrii S. Kulbatskii, Mikhail A. Shulepko, Alexander S. Paramonov, Elizaveta M. Chernaya, Yulia A. Logashina, Yaroslav A. Andreev, Mikhail P. Kirpichnikov, Zakhar O. Shenkarev
Publikováno v:
Toxins, Vol 15, Iss 6, p 378 (2023)
Phα1β (PnTx3–6) is a neurotoxin from the spider Phoneutria nigriventer venom, originally identified as an antagonist of two ion channels involved in nociception: N-type voltage-gated calcium channel (CaV2.2) and TRPA1. In animal models, Phα1β a
Externí odkaz:
https://doaj.org/article/f4d10ab60deb48d7b5091e7ada0f2188
Intramolecular Hydrogen Bonding in N6-Substituted 2-Chloroadenosines: Evidence from NMR Spectroscopy
Autor:
Maria Ya. Berzina, Barbara Z. Eletskaya, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ilya V. Fateev, Olga N. Zhavoronkova, Arthur R. Bashorin, Alexandra O. Arnautova, Olga S. Smirnova, Konstantin V. Antonov, Alexander S. Paramonov, Maxim A. Dubinnyi, Roman S. Esipov, Anatoly I. Miroshnikov, Irina D. Konstantinova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9697 (2023)
Two forms were found in the NMR spectra of N6-substituted 2-chloroadenosines. The proportion of the mini-form was 11–32% of the main form. It was characterized by a separate set of signals in COSY, 15N-HMBC and other NMR spectra. We assumed that th
Externí odkaz:
https://doaj.org/article/c39dc45950364611958e951f8606b166
Autor:
Barbara Z. Eletskaya, Maria Ya. Berzina, Ilya V. Fateev, Alexei L. Kayushin, Elena V. Dorofeeva, Olga I. Lutonina, Ekaterina A. Zorina, Konstantin V. Antonov, Alexander S. Paramonov, Inessa S. Muzyka, Olga S. Zhukova, Mikhail V. Kiselevskiy, Anatoly I. Miroshnikov, Roman S. Esipov, Irina D. Konstantinova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6223 (2023)
A number of purine arabinosides containing chiral amino acid amides at the C6 position of the purine were synthesized using a transglycosylation reaction with recombinant E. coli nucleoside phosphorylases. Arsenolysis of 2-chloropurine ribosides with
Externí odkaz:
https://doaj.org/article/f29fcfdbffac4cb9834047e3156d7761
Autor:
Irina S. Panina, Sergey V. Balandin, Andrey V. Tsarev, Anton O. Chugunov, Andrey A. Tagaev, Ekaterina I. Finkina, Daria V. Antoshina, Elvira V. Sheremeteva, Alexander S. Paramonov, Jasmin Rickmeyer, Gabriele Bierbaum, Roman G. Efremov, Zakhar O. Shenkarev, Tatiana V. Ovchinnikova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1332 (2023)
To date, a number of lantibiotics have been shown to use lipid II—a highly conserved peptidoglycan precursor in the cytoplasmic membrane of bacteria—as their molecular target. The α-component (Lchα) of the two-component lantibiotic lichenicidin
Externí odkaz:
https://doaj.org/article/02f68f5966884e5d99c68990b5f42424
Autor:
Maxim M. Zaigraev, Ekaterina N. Lyukmanova, Alexander S. Paramonov, Zakhar O. Shenkarev, Anton O. Chugunov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 11 (2022)
Ly6/uPAR proteins regulate many essential functions in the nervous and immune systems and epithelium. Most of these proteins contain single β-structural LU domains with three protruding loops and are glycosylphosphatidylinositol (GPI)-anchored to a
Externí odkaz:
https://doaj.org/article/2e52464b0b17425188fd318ee0cadc56