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of 3
pro vyhledávání: '"Alexander Rudich"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12271 (2022)
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm initiated by the presence of the fusion gene BCR::ABL1. The development of tyrosine kinase inhibitors (TKIs) highly specific to p210BCR-ABL1, the constitutively active tyrosine kinase en
Externí odkaz:
https://doaj.org/article/e575c2f6d02442e2b22e1ed943d4cfe0
Autor:
Chinmayee Goda, Sofia Kolovich, Alexander Rudich, Malith Karunasiri, Rohan Kulkarni, Girish Rajgolikar, Lotus Neidemire-Colley, Satishkumar Singh, Anuvrat Sircar, Parvathi Ranganathan, Ramiro Garzon, Lalit Sehgal, Adrienne M. Dorrance
Publikováno v:
Experimental Hematology.
Autor:
Chinmayee Goda, Rohan Kulkarni, Alexander Rudich, Malith Karunasiri, Girish Rajgolikar, Bethany Mundy-Bosse, Ramiro Garzon, Elaine Mardis, Katherine Miller, Adrienne M. Dorrance
Publikováno v:
Cancer Research. 83:2496-2496
Acute myeloid leukemia (AML) is a heterogenous disease that develops due to genetic mutations occurring within hematopoietic stem/progenitor cells (HSPCs), giving rise to clonal proliferation. Mutated leukemic stem cells (LSCs) can remain dormant wit