Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alexander Rosov"'
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285338 (2023)
In sheep, ~30% of fetuses do not survive till parturition, and 17.7% of the multifetal pregnancies experience partial litter loss (PLL). In humans, multifetal pregnancies are associated with a higher risk of perinatal mortality. Therefore, the object
Externí odkaz:
https://doaj.org/article/41394397091f4d6ab771e03b2a624bf4
Autor:
Mugagga Kalyesubula, Ramgopal Mopuri, Alexander Rosov, Tamir Alon, Nir Edery, Uzi Moallem, Hay Dvir
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Hepatic steatosis is strongly associated with chronic liver disease and systemic metabolic disorder. Adipose lipolysis is a recognized principal source of intrahepatic fat in various metabolic disorders, including non-alcoholic fatty liver d
Externí odkaz:
https://doaj.org/article/50c5163424224121a15cac57f3cef2f1
Autor:
Mugagga Kalyesubula, Ramgopal Mopuri, Jimmy Asiku, Alexander Rosov, Sara Yosefi, Nir Edery, Samuel Bocobza, Uzi Moallem, Hay Dvir
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 3 (2021)
Fatty liver is an abnormal metabolic condition of excess intrahepatic fat. This condition, referred to as hepatic steatosis, is tightly associated with chronic liver disease and systemic metabolic morbidity. The most prevalent form in humans, i.e. no
Externí odkaz:
https://doaj.org/article/a72dda927552440584327c959a7f16b5
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2021)
Fatty liver represents a significant metabolic pathology of excess intrahepatic fat in domestic animals and humans. Quantification of hepatic-fat content is therefore essential for diagnosis and investigation of liver and metabolic disease. However,
Externí odkaz:
https://doaj.org/article/1a3e50fa9a8e4cf496ff301282716ace
Publikováno v:
Nutrients, Vol 13, Iss 10, p 3463 (2021)
As a precursor for a universal metabolic coenzyme, vitamin B1, also known as thiamine, is a vital nutrient in all living organisms. We previously found that high-dose thiamine therapy prevents overnutrition-induced hepatic steatosis in sheep by enhan
Externí odkaz:
https://doaj.org/article/a74be6c7e7674d51b2fd19ad9ff7e5c6
Publikováno v:
Animals, Vol 9, Iss 10, p 731 (2019)
Negative energy balance (NEB) is a state of insufficient dietary-energy consumption, characterized by the breakdown of adipose fat to meet the physiological energy expenditure. Extensive NEB, as common in high-yielding transitioning ruminants, drives
Externí odkaz:
https://doaj.org/article/be27509814564ffe8b6bca4cc12e1cac
Autor:
Hay Dvir, Ramgopal Mopuri, Uzi Moallem, Mugagga Kalyesubula, Nir Edery, Alexander Rosov, Tamir Alon
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Hepatic steatosis is strongly associated with chronic liver disease and systemic metabolic disorder. Adipose lipolysis is a recognized principal source of intrahepatic fat in various metabolic disorders, including non-alcoholic fatty liver disease. W
Autor:
Esther Yamin, Elisha Gootwine, Alexey Obolensky, Eyal Banin, Raaya Ezra-Elia, Edward Averbukh, Ron Ofri, William W. Hauswirth, Hay Dvir, Maya Ross, Hen Honig, Alexander Rosov
Publikováno v:
Human Gene Therapy. 31:719-729
Gene augmentation therapy based on subretinal delivery of adeno-associated viral (AAV) vectors is proving to be highly efficient in treating several inherited retinal degenerations. However, due to potential complications and drawbacks posed by subre
Autor:
Edward Averbukh, William W. Hauswirth, Hen Honig, Maya Ross, Alexander Rosov, Eyal Banin, Alexey Obolensky, Raaya Ezra-Elia, Elisha Gootwine, Ron Ofri
Publikováno v:
Human Gene Therapy. 29:1376-1386
Achromatopsia causes severely reduced visual acuity, photoaversion, and inability to discern colors due to cone photoreceptor dysfunction. In 2010, we reported on day-blindness in sheep caused by a...
Autor:
Uzi Moallem, Mugagga Kalyesubula, Hay Dvir, Jimmy Asiku, Samuel Bocobza, Ramgopal Mopuri, Alexander Rosov, Nir Edery, Sara Yosefi
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 3 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms
article-version (VoR) Version of Record
Fatty liver is an abnormal metabolic condition of excess intrahepatic fat. This condition, referred to as hepatic steatosis, is tightly associated with chronic liver disease and systemic metabolic morbidity. The most prevalent form in humans, i.e. no