Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Alexander R. Pinto"'
Autor:
Anna E. Williamson, Sanuri Liyanage, Mohammadhossein Hassanshahi, Malathi S. I. Dona, Deborah Toledo-Flores, Dang X. A. Tran, Catherine Dimasi, Nisha Schwarz, Sanuja Fernando, Thalia Salagaras, Aaron Long, Jan Kazenwadel, Natasha L. Harvey, Grant R. Drummond, Antony Vinh, Vashe Chandrakanthan, Ashish Misra, Zoltan Neufeld, Joanne T. M. Tan, Luciano Martelotto, Jose M. Polo, Claudine S. Bonder, Alexander R. Pinto, Shiwani Sharma, Stephen J. Nicholls, Christina A. Bursill, Peter J. Psaltis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Converging evidence indicates that extra-embryonic yolk sac is the source of both macrophages and endothelial cells in adult mouse tissues. Prevailing views are that these embryonically derived cells are maintained after birth by proliferati
Externí odkaz:
https://doaj.org/article/d2b62685f49a4c7f8deedee2fe7c08c9
Autor:
Charles D. Cohen, Miles J. De Blasio, Gabriella E. Farrugia, Malathi S.I. Dona, Ian Hsu, Darnel Prakoso, Helen Kiriazis, Crisdion Krstevski, David M. Nash, Mandy Li, Taylah L. Gaynor, Minh Deo, Grant R. Drummond, Rebecca H. Ritchie, Alexander R. Pinto
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107759- (2023)
Summary: Diabetes is associated with a significantly elevated risk of heart failure. However, despite extensive efforts to characterize the phenotype of the diabetic heart, the molecular and cellular protagonists that underpin cardiac pathological re
Externí odkaz:
https://doaj.org/article/d504173b55ce4ebe84dc49ae7fdf7e65
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Cardiac fibrosis is insidious, accelerating cardiovascular diseases, heart failure, and death. With a notable lack of effective therapies, advances in both understanding and targeted treatment of fibrosis are urgently needed. Remodelling of
Externí odkaz:
https://doaj.org/article/b4589dc7988e402d98b0b463576cb69b
Autor:
Charles D. Cohen, Miles J. De Blasio, Man K. S. Lee, Gabriella E. Farrugia, Darnel Prakoso, Crisdion Krstevski, Minh Deo, Daniel G. Donner, Helen Kiriazis, Michelle C. Flynn, Taylah L. Gaynor, Andrew J. Murphy, Grant R. Drummond, Alexander R. Pinto, Rebecca H. Ritchie
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Diabetes is associated with a significantly elevated risk of cardiovascular disease and its specific pathophysiology remains unclear. Recent studies have changed our understanding of cardiac cellularity, with cellular changes acco
Externí odkaz:
https://doaj.org/article/88aaad0eb056450fa3ffbe56d0335c20
Autor:
Gabriella E. Farrugia, Micheal A. McLellan, Kate L. Weeks, Aya Matsumoto, Charles D. Cohen, Crisdion Krstevski, Taylah L. Gaynor, Adam C. Parslow, Julie R. McMullen, Alexander R. Pinto
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100866- (2021)
Summary: This protocol features parallel isolation of myocytes and non-myocytes from murine hearts. It was designed with considerations for (1) time required to extract cardiac cells, (2) cell viability, and (3) protocol scalability. Here, a peristal
Externí odkaz:
https://doaj.org/article/e554ac6acc834cce8edb2df50ff09a7e
Autor:
Daniel A. Skelly, Galen T. Squiers, Micheal A. McLellan, Mohan T. Bolisetty, Paul Robson, Nadia A. Rosenthal, Alexander R. Pinto
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 600-610 (2018)
Characterization of the cardiac cellulome, the network of cells that form the heart, is essential for understanding cardiac development and normal organ function and for formulating precise therapeutic strategies to combat heart disease. Recent studi
Externí odkaz:
https://doaj.org/article/dbea1aba05314308adbb53b774b7db8b
Publikováno v:
Stem Cell Research, Vol 13, Iss 3, Pp 705-714 (2014)
Macrophages are an immune cell type found in every organ of the body. Classically, macrophages are recognised as housekeeping cells involved in the detection of foreign antigens and danger signatures, and the clearance of tissue debris. However, macr
Externí odkaz:
https://doaj.org/article/922962cfe915480f92a57a98e8830876
Autor:
Malathi S. I. Dona, Ian Hsu, Alex I. Meuth, Scott M. Brown, Chastidy A. Bailey, Christian G. Aragonez, Jacob J. Russell, Crisdion Krstevski, Annayya R. Aroor, Bysani Chandrasekar, Luis A. Martinez-Lemus, Vincent G. DeMarco, Laurel A. Grisanti, Iris Z. Jaffe, Alexander R. Pinto, Shawn B. Bender
Publikováno v:
Basic Research in Cardiology. 118
Coronary microvascular dysfunction (CMD) is associated with cardiac dysfunction and predictive of cardiac mortality in obesity, especially in females. Clinical data further support that CMD associates with development of heart failure with preserved
Autor:
Andrew J. Murphy, Gabriella E. Farrugia, Man K.S. Lee, Miles J. De Blasio, Minh Deo, Charles D. Cohen, Alexander R. Pinto, Helen Kiriazis, Darnel Prakoso, Rebecca Helen Ritchie, Michelle C Flynn, Crisdion Krstevski, D. Donner, Grant R Drummond, Taylah L. Gaynor
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-12 (2021)
Cardiovascular Diabetology
Cardiovascular Diabetology
Background Diabetes is associated with a significantly elevated risk of cardiovascular disease and its specific pathophysiology remains unclear. Recent studies have changed our understanding of cardiac cellularity, with cellular changes accompanying
Autor:
Alexander R. Pinto
Publikováno v:
Circulation Research. 129:1036-1038