Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexander R. Pelletier"'
Autor:
Karl W. Kroll, Nima E. Mokaram, Alexander R. Pelletier, David E. Frankhouser, Maximillian S. Westphal, Paige A. Stump, Cameron L. Stump, Ralf Bundschuh, James S. Blachly, Pearlly Yan
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 3, Pp 7-14 (2014)
Externí odkaz:
https://doaj.org/article/b76bfd8b0fc346529c289b9067bdff04
Autor:
Yu Yan, Jyun-Yu Jiang, Mingzhou Fu, Ding Wang, Alexander R. Pelletier, Dibakar Sigdel, Dominic C.M. Ng, Wei Wang, Peipei Ping
Publikováno v:
Cell reports methods, vol 3, iss 3
Cell Rep Methods
Cell Rep Methods
We present a deep-learning-based platform, MIND-S, for protein post-translational modification (PTM) predictions. MIND-S employs a multi-head attention and graph neural network and assembles a 15-fold ensemble model in a multi-label strategy to enabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb117996062eef9f12b454abcb40003c
https://escholarship.org/uc/item/5sz4w8jh
https://escholarship.org/uc/item/5sz4w8jh
Autor:
Alexander R. Pelletier, Viyashini Vijithakumar, Sabrina Robichaud, Sylvain Huard, Mathieu Lavallée-Adam, Daniel Figeys, David P. Cook, Barbara C. Vanderhyden, Garrett Fairman, Mireille Ouimet, Esther Mak, Kristin Baetz
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Macrophage autophagy is a highly anti-atherogenic process that promotes the catabolism of cytosolic lipid droplets (LDs) to maintain cellular lipid homeostasis. Selective autophagy relies on tags such as ubiquitin and a set of selectivity factors inc
Autor:
Bilal Mirza, Dibakar Sigdel, Neo Christopher Chung, Ding Wang, Alexander R. Pelletier, Peipei Ping, Wei Wang, Howard Choi
Publikováno v:
Journal of molecular and cellular cardiology
Objective During cardiovascular disease progression, molecular systems of myocardium (e.g., a proteome) undergo diverse and distinct changes. Dynamic, temporally-regulated alterations of individual molecules underlie the collective response of the he
Autor:
Mathieu Lavallée-Adam, Yun-En Chung, Zhibin Ning, Alexander R. Pelletier, Nora Wong, Daniel Figeys
Publikováno v:
Journal of the American Society for Mass Spectrometry. 31(7)
Mass spectrometry-based proteomics technologies are the prime methods for the high-throughput identification of proteins in complex biological samples. Nevertheless, there are still technical limitations that hinder the ability of mass spectrometry t
Autor:
Salvador Martínez-Bartolomé, Mathieu Lavallée-Adam, Low W, James J. Moresco, Pinto Afm, Alexander R. Pelletier, Michael Petrascheck, Yates, Jolene K. Diedrich
When coupled to mass spectrometry (MS), energetics-based protein separation (EBPS) techniques, such as thermal shift assay, have shown great potential to identify the targets of a drug on a proteome scale. Nevertheless, the computational analyses ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cbf4dc5b7318346abb0d85e9fbb98f
https://doi.org/10.1101/513663
https://doi.org/10.1101/513663
Autor:
Mathieu Lavalle-Adam, Nam-Kyung Yu, Salvador Martínez-Bartolomé, John R. Yates, Daniel B. McClatchy, Alexander R. Pelletier, Reesha R. Patel, Susan B. Powell, Marissa Roberto
Publikováno v:
ACS chemical neuroscience. 9(12)
Kinases are a major clinical target for human diseases. Identifying the proteins that interact with kinases in vivo will provide information on unreported substrates and will potentially lead to more specific methods for therapeutic kinase regulation
Autor:
Alexander R. Pelletier, Taha M. Topiwala, Jackson A. Killian, Ralf Bundschuh, David Frankhouser, Pearlly S. Yan
Publikováno v:
BMC Genomics
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Background Gene fusions often occur in cancer cells and in some cases are the main driver of oncogenesis. Correct identification of oncogenic gene fusions thus has implications for targeted cancer therapy. Recognition of this potential has led to the
Autor:
Nima E. Mokaram, Karl Kroll, Cameron L. Stump, Alexander R. Pelletier, Paige A. Stump, Maximillian Westphal, David Frankhouser, Ralf Bundschuh, Pearlly S. Yan, James S. Blachly
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 3, Pp 7-14 (2014)
Cancer Informatics, Vol 13s3 (2014)
Cancer Informatics
Cancer Informatics, Vol 13s3 (2014)
Cancer Informatics
QuaCRS ( Quality Control for RNA- Seq) is an integrated, simplified quality control (QC) system for RNA-seq data that allows easy execution of several open-source QC tools, aggregation of their output, and the ability to quickly identify quality issu