Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexander R. Kazarov"'
Autor:
Tatiana V. Kolesnikova, Alexander R. Kazarov, Madeleine E. Lemieux, Marc A. Lafleur, Santosh Kesari, Andrew L. Kung, Martin E. Hemler
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 1, Pp 77-86 (2009)
EWI-2, a cell surface IgSF protein, is highly expressed in normal human brain but is considerably diminished in glioblastoma tumors and cell lines. Moreover, loss of EWI-2 expression correlated with a shorter survival time in human glioma patients, s
Externí odkaz:
https://doaj.org/article/f81b28a80d654531bfba39a55afd3d4e
Autor:
Martin E. Hemler, Myles Brown, Jack L. Strominger, Milena M. Andzelm, Alexander R. Kazarov, Chandan Sharma, Pengcheng Zhou, Maria I. Torres-Arzayus, Andrea L. Richardson, Xiuwei H. Yang
Supplementary Table 1 from CD151 Accelerates Breast Cancer by Regulating α6 Integrin Function, Signaling, and Molecular Organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e3333081758c76f65d9819d62c760c
https://doi.org/10.1158/0008-5472.22376499.v1
https://doi.org/10.1158/0008-5472.22376499.v1
Autor:
Jack L. Strominger, Alexander R. Kazarov, Chandan Sharma, Maria I. Torres-Arzayus, Andrea L. Richardson, Martin E. Hemler, Milena M. Andzelm, Myles Brown, Pengcheng Zhou, Xiuwei H. Yang
Publikováno v:
Cancer Research. 68:3204-3213
CD151, a master regulator of laminin-binding integrins (α6β4, α6β1, and α3β1), assembles these integrins into complexes called tetraspanin-enriched microdomains. CD151 protein expression is elevated in 31% of human breast cancers and is even mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe8ff1e86d204f2347425da01b6f83e
https://doi.org/10.1158/0008-5472.can-07-2949
https://doi.org/10.1158/0008-5472.can-07-2949
Publikováno v:
Proceedings of the National Academy of Sciences. 100:7616-7621
The tetraspanin CD151 molecule associates specifically with laminin-binding integrins, including α6β1. To probe strength of α6β1-dependent adhesion to laminin-1, defined forces (0–1.5 nN) were applied to magnetic laminin-coated microbeads bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d9a9a421fe10b1d19ea0f699163d34
https://doi.org/10.1073/pnas.1337546100
https://doi.org/10.1073/pnas.1337546100
Publikováno v:
The Journal of Cell Biology
The alpha 3 beta 1 integrin shows strong, stoichiometric, direct lateral association with the tetraspanin CD151. As shown here, an extracellular CD151 site (QRD(194-196)) is required for strong (i.e., Triton X-100-resistant) alpha 3 beta 1 associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6397893dba9531589869b78cf8b80446
https://doi.org/10.1083/jcb.200204056
https://doi.org/10.1083/jcb.200204056
Autor:
Martin E. Hemler, Xin Zhang, Christopher S. Stipp, Xiuwei Yang, Alexa L. Bontrager, Alexander R. Kazarov
Publikováno v:
Molecular Biology of the Cell. 13:1-11
Upon plating on basement membrane Matrigel, NIH3T3 cells formed an anastomosing network of cord-like structures, inhibitable by anti-alpha6beta1 integrin antibodies. For NIH3T3 cells transfected with human CD151 protein, the formation of a cord-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97eca68d2d7e370cbafa0a5244ea3df4
https://doi.org/10.1091/mbc.01-10-0481
https://doi.org/10.1091/mbc.01-10-0481
Publikováno v:
Nature Genetics. 14:415-420
Using a new strategy for tumour suppressor gene isolation based on subtractive hybridization and the subsequent selection of transforming 'genetic suppressor elements', we have cloned a novel gene called ING1 encoding a 33-kD protein (p33ING1) that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcc7a60e446e05c751db6ddf887506a
https://doi.org/10.1038/ng1296-415
https://doi.org/10.1038/ng1296-415
Autor:
Martin E. Hemler, Shannon J. Turley, Alexander R. Kazarov, Mathieu Epardaud, Kutlu G. Elpek, Yoshito Takeda, Qinglin Li
Publikováno v:
Blood
Blood, American Society of Hematology, 2011, 118 (2), pp.464-472. ⟨10.1182/blood-2010-08-302240⟩
Blood, American Society of Hematology, 2011, 118 (2), pp.464-472. ⟨10.1182/blood-2010-08-302240⟩
International audience; Tetraspanin protein CD151 on tumor cells supports invasion and metastasis. In the present study, we show that host animal CD151 also plays a critical role. CD151-null mice showed markedly diminished experimental lung metastasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11de8fe0a73fc7f194ab7fefc9cd3c51
https://hal.inrae.fr/hal-02648292
https://hal.inrae.fr/hal-02648292
Autor:
Igor B. Roninson, Rama Thimmapaya, Sergey A. Axenovich, Alexander R. Kazarov, Ilya Mazo, Andrei V. Gudkov
We describe a general strategy for cloning mammalian genes whose downregulation results in a selectable phenotype. This strategy is based on expression selection of genetic suppressor elements (GSEs), cDNA fragments encoding either specific peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc47bf9c4941f5339f34ffc4d661edd8
https://europepmc.org/articles/PMC43658/
https://europepmc.org/articles/PMC43658/
Autor:
Martin E. Hemler, Madeleine E. Lemieux, Alexander R. Kazarov, Tatiana V. Kolesnikova, Andrew L. Kung, Santosh Kesari, Marc A. Lafleur
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 1, Pp 77-86 (2009)
EWI-2, a cell surface IgSF protein, is highly expressed in normal human brain but is considerably diminished in glioblastoma tumors and cell lines. Moreover, loss of EWI-2 expression correlated with a shorter survival time in human glioma patients, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c2664963c8cddc9263d477de1f0bb6
https://doi.org/10.1593/neo.81180
https://doi.org/10.1593/neo.81180