Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Alexander R Horswill"'
Autor:
Katrin Schilcher, Morgan M Severn, Christian Jenul, Young-Saeng C Avina, Rebecca A Keogh, Alexander R Horswill
Publikováno v:
PLoS Biology, Vol 22, Iss 1, p e3002451 (2024)
Lipoproteins of the opportunistic pathogen Staphylococcus aureus play a crucial role in various cellular processes and host interactions. Consisting of a protein and a lipid moiety, they support nutrient acquisition and anchor the protein to the bact
Externí odkaz:
https://doaj.org/article/d4eff5b776f74c0692cc03063a86d52b
Autor:
Flavia G Costa, Alexander R Horswill
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010512 (2022)
Skin health is influenced by the composition and integrity of the skin barrier. The healthy skin surface is an acidic, hypertonic, proteinaceous, and lipid-rich environment that microorganisms must adapt to for survival, and disruption of this enviro
Externí odkaz:
https://doaj.org/article/23b3720f38fc4842962145a085684f1a
Autor:
Lisanne de Vor, Bruce van Dijk, Kok van Kessel, Jeffrey S Kavanaugh, Carla de Haas, Piet C Aerts, Marco C Viveen, Edwin C Boel, Ad C Fluit, Jakub M Kwiecinski, Gerard C Krijger, Ruud M Ramakers, Freek J Beekman, Ekaterina Dadachova, Marnix GEH Lam, H Charles Vogely, Bart CH van der Wal, Jos AG van Strijp, Alexander R Horswill, Harrie Weinans, Suzan HM Rooijakkers
Publikováno v:
eLife, Vol 11 (2022)
Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach
Externí odkaz:
https://doaj.org/article/f9dfe179409a4ffabf19a218bc324d32
Autor:
Morgan M Brown, Alexander R Horswill
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009026 (2020)
Our skin is our first line of defense against environmental and pathogenic challenges. It is densely populated by a flora of bacteria, fungi, and viruses that normally interact with each other and with our immune system to promote skin health and hom
Externí odkaz:
https://doaj.org/article/9514af7e11c54d9ba18f54122ad4f839
Autor:
Matthew J Pestrak, Tripti Thapa Gupta, Devendra H Dusane, Doug V Guzior, Amelia Staats, Jan Harro, Alexander R Horswill, Paul Stoodley
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231791 (2020)
Periprosthetic joint infections (PJIs) are a devastating complication that occurs in 2% of patients following joint replacement. These infections are costly and difficult to treat, often requiring multiple corrective surgeries and prolonged antimicro
Externí odkaz:
https://doaj.org/article/46cde1d2ca554ea7b425c975e96ec373
Autor:
Matthew J Pestrak, Tripti Thapa Gupta, Devendra H Dusane, Doug V Guzior, Amelia Staats, Jan Harro, Alexander R Horswill, Paul Stoodley
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233534 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0231791.].
Externí odkaz:
https://doaj.org/article/315828434da347408ad6fc3dca49fbee
Autor:
Jakub M Kwiecinski, Heidi A Crosby, Claire Valotteau, Joseph A Hippensteel, Manasa K Nayak, Anil K Chauhan, Eric P Schmidt, Yves F Dufrêne, Alexander R Horswill
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007800 (2019)
Staphylococcus aureus is a leading cause of endovascular infections. This bacterial pathogen uses a diverse array of surface adhesins to clump in blood and adhere to vessel walls, leading to endothelial damage, development of intravascular vegetation
Externí odkaz:
https://doaj.org/article/a054eb9fbd2c4c719f03495349f5698f
Autor:
Tiffany Y Borbón, Breanna M Scorza, Gwendolyn M Clay, Fellipe Lima Nobre de Queiroz, Alan J Sariol, Jayden L Bowen, Yani Chen, Bayan Zhanbolat, Corey P Parlet, Diogo G Valadares, Suzanne L Cassel, William M Nauseef, Alexander R Horswill, Fayyaz S Sutterwala, Mary E Wilson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007247 (2019)
Cutaneous leishmaniasis (CL) is a parasitic disease causing chronic, ulcerating skin lesions. Most humans infected with the causative Leishmania protozoa are asymptomatic. Leishmania spp. are usually introduced by sand flies into the dermis of mammal
Externí odkaz:
https://doaj.org/article/d356486971d14c3ab0729d9b3e40b87f
Autor:
Heidi A Crosby, Patrick M Schlievert, Joseph A Merriman, Jessica M King, Wilmara Salgado-Pabón, Alexander R Horswill
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005604 (2016)
Staphylococcus aureus is a human commensal and opportunistic pathogen that causes devastating infections in a wide range of locations within the body. One of the defining characteristics of S. aureus is its ability to form clumps in the presence of s
Externí odkaz:
https://doaj.org/article/112e4fe603de4d29a248d1a01dbdabba
Autor:
Rahel Decker, Christoph Burdelski, Melanie Zobiak, Henning Büttner, Gefion Franke, Martin Christner, Katharina Saß, Bernd Zobiak, Hanae A Henke, Alexander R Horswill, Markus Bischoff, Stephanie Bur, Torsten Hartmann, Carolyn R Schaeffer, Paul D Fey, Holger Rohde
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004735 (2015)
Virulence of the nosocomial pathogen Staphylococcus epidermidis is crucially linked to formation of adherent biofilms on artificial surfaces. Biofilm assembly is significantly fostered by production of a bacteria derived extracellular matrix. However
Externí odkaz:
https://doaj.org/article/ccb8804bc78a49ea9f772ba22188c9c0