Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexander R, Carr"'
Autor:
Marie N. Bongiovanni, Julien Godet, Mathew H. Horrocks, Laura Tosatto, Alexander R. Carr, David C. Wirthensohn, Rohan T. Ranasinghe, Ji-Eun Lee, Aleks Ponjavic, Joelle V. Fritz, Christopher M. Dobson, David Klenerman, Steven F. Lee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Many super-resolution imaging techniques use fluorescence emission intensity to obtain precise positional information, but other spectral information is ignored. Here, the authors develop a method that records the spectrum and position of single dye
Externí odkaz:
https://doaj.org/article/abb20732e92142cb98457e9515465e87
Autor:
Thomas N. Snaddon, Tuomas P. J. Knowles, David Klenerman, Sonia Gandhi, De S, Ji-Eun Lee, Henrik Zetterberg, Aleks Ponjavic, Do D, Baudrexel I, Steven F. Lee, Francesco Simone Ruggeri, Pearson C, Juan A. Varela, Alexander R. Carr, Margarida Rodrigues, Klara Kulenkampff, Bhattacharjee P, Brinkmalm A
The composition of soluble toxic protein aggregates formed in vivo is currently unknown in neurodegenerative diseases, due to their ultra-low concentration in human biofluids and their high degree of heterogeneity. We introduce the structure-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e359d1c443659ed7fe2b9ba599e2721
https://doi.org/10.21203/rs.3.rs-81521/v1
https://doi.org/10.21203/rs.3.rs-81521/v1
Autor:
Edward W. Sanders, Alexander R. Carr, Ezra Bruggeman, Markus Koerbel, Ana Mafalda Santos, James T. McColl, Kevin O'Holleran, David Klenerman, Simon J. Davis, Aleks Ponjavic, Steven F. Lee
Publikováno v:
Biophysical Journal. 121:140a
Autor:
Lisa-Maria Needham, Steven F. Lee, Simon J. Davis, Ricardo Henriques, Christophe Leterrier, Ana Filipa L.O.M. Santos, James McColl, Anoushka Handa, Alexander R. Carr, Aleks Ponjavic, Daniel Esteban-Ferrer, Alexandre Kitching, Alexander Spark
Publikováno v:
Nat Methods
Nature Methods
Nature Methods, Nature Publishing Group, 2020, ⟨10.1038/s41592-020-0962-1⟩
Nature Methods, 2020, ⟨10.1038/s41592-020-0962-1⟩
Nature Methods
Nature Methods, Nature Publishing Group, 2020, ⟨10.1038/s41592-020-0962-1⟩
Nature Methods, 2020, ⟨10.1038/s41592-020-0962-1⟩
International audience; vLUME is a virtual reality software package designed to render large three-dimensional single-molecule localization micros-copy datasets. vLUME features include visualization, seg-mentation, bespoke analysis of complex local g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90f64dd13cff826b00e76282596d309
Autor:
Peter Jönsson, Simon J. Davis, David Klenerman, Omer Dushek, Alan E. Lindsay, Ana Filipa L.O.M. Santos, Steven F. Lee, Matthieu Palayret, Ricardo A. Fernandes, Aleks Ponjavic, Charlotte Macleod, J. C. Tzou, Veronica T. Chang, Andreas Tilevik, Alexander R. Carr, Kristina A. Ganzinger, B. Christoffer Lagerholm
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance One approach to testing biological theories is to determine if they are predictive. We have developed a simple, theoretical treatment of T cell receptor (TCR) triggering that relies on just two physical principles: (i) the time TCRs spen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6989644200ef7eb22f78a0672b9531c6
https://www.repository.cam.ac.uk/handle/1810/293127
https://www.repository.cam.ac.uk/handle/1810/293127
Autor:
Yuewen Zhang, David Klenerman, Daniel Finley, Ji-Eun Lee, Yu Ye, Anna Lippert, Steven F. Lee, Alexander R. Carr, Aleks Ponjavic
Proteasomes are molecular machineries responsible for regulated protein degradation and general homeostasis. The distribution of this degradation capacity is reflected by the cellular localisation of proteasomal particles. Here we combine super-resol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469578a7d4658fb076f4e94f9b05ef4f
https://doi.org/10.1101/487702
https://doi.org/10.1101/487702
Publikováno v:
Optics express. 26(4)
Super-resolution techniques that localize single molecules in three dimensions through point spread function (PSF) engineering are very sensitive to aberrations and optical alignment. Here we show how double-helix point spread function is affected by
Autor:
James McCol, Dave Klenerman, Ji-Eun Lee, Steven F. Lee, Simon J. Davis, Ana Filipa L.O.M. Santos, Aleks Ponjavic, Alexander R. Carr
Publikováno v:
Biophysical Journal. 110:485a
Most optical imaging of individual cells has been conducted in 2D on flat glass or culture plastic. Not only is this very abstract from the biological environment and does not imitate physiological conditions, but it may lead to unwanted perturbation