Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alexander Q Wixom"'
Autor:
Cheryl A Keller, Alexander Q Wixom, Elisabeth F Heuston, Belinda Giardine, Chris C -S Hsiung, Maria R Long, Amber Miller, Stacie M Anderson, April Cockburn, Gerd A Blobel, David M Bodine, Ross C Hardison
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
AbstractChromatin immunoprecipitation followed by massively parallel, high throughput sequencing (ChIP-seq) is the method of choice for genome-wide identification of DNA segments bound by specific transcription factors or in chromatin with particular
Externí odkaz:
https://doaj.org/article/187ad77994884baf9b47056148b28010
Autor:
Anuradha Krishnan, Nazli Begum Ozturk, Kaiyel A. Cutshaw, Maria Eugenia Guicciardi, Takashi Kitagataya, Kirsta E. Olson, Kevin D. Pavelko, William Sherman, Alexander Q. Wixom, Nidhi Jalan-Sakrikar, Michelle Baez-Faria, Florencia Gutierrez, Gregory J. Gores
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Ductular reactive (DR) cells exacerbate cholestatic liver injury and fibrosis. Herein, we posit that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) emanates from recruited macrophages and restrains DR cell expansion, thereby
Externí odkaz:
https://doaj.org/article/36650741471d4bd18d0ae191c826688e
Autor:
Nidhi Jalan-Sakrikar, Abid Anwar, Usman Yaqoob, Can Gan, Anthony B. Lagnado, Alexander Q. Wixom, Diana Jurk, Robert C. Huebert
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Cellular senescence and biliary fibrosis are prototypical features of obliterative cholangiopathies, such as primary sclerosing cholangitis (PSC). Telomere dysfunction can lead to senescence either through telomere erosion or damaged telomeres. Our g
Externí odkaz:
https://doaj.org/article/3bb8d0fb2fe74071a92357a1385ba71e
Autor:
Alexander Q. Wixom, N. Carol Casavant, Timothy J. Sonnen, Joseph C. Kuhl, Fangming Xiao, Louise‐Marie Dandurand, Allan B. Caplan
Publikováno v:
The Plant Genome, Vol 13, Iss 2, Pp n/a-n/a (2020)
Abstract Many researchers today are looking for mechanisms underlying plant defenses against nematodes by identifying differentially expressed genes in domesticated hosts. In order to provide a different perspective, we analyzed the root transcriptom
Externí odkaz:
https://doaj.org/article/e6b2d352d1f44d85923c02e7fb1df654
Autor:
Guanjue Xiang, Xi He, Belinda M. Giardine, Kathryn J. Weaver, Dylan J. Taylor, Rajiv C. McCoy, Camden Jansen, Cheryl A. Keller, Alexander Q. Wixom, April Cockburn, Amber Miller, Qian Qi, Yanghua He, Yichao Li, Jens Lichtenberg, Elisabeth F. Heuston, Stacie M. Anderson, Jing Luan, Marit W. Vermunt, Feng Yue, Michael E.G. Sauria, Michael C. Schatz, James Taylor, Berthold Göttgens, Jim R. Hughes, Douglas R. Higgs, Mitchell J. Weiss, Yong Cheng, Gerd A. Blobel, David Bodine, Yu Zhang, Qunhua Li, Shaun Mahony, Ross C. Hardison
Knowledge of locations and activities ofcis-regulatory elements (CREs) is needed to decipher basic mechanisms of gene regulation and to understand the impact of genetic variants on complex traits. Previous studies identified candidate CREs (cCREs) us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef37c806f6c18c3930749db34dc396f5
https://doi.org/10.1101/2023.04.02.535219
https://doi.org/10.1101/2023.04.02.535219
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Supplementary Tables S4 to S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23f15947587a1ecf902426e96af9667
https://doi.org/10.1158/0008-5472.22430146
https://doi.org/10.1158/0008-5472.22430146
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Supplementary Figures S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6288dcab26989b52b9da6dbefd87adf9
https://doi.org/10.1158/0008-5472.22430152.v1
https://doi.org/10.1158/0008-5472.22430152.v1
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Supplementary Materials & Methods, Supplementary Tables S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0dcc1611a699d31c3a57d2704a986a
https://doi.org/10.1158/0008-5472.22430149.v1
https://doi.org/10.1158/0008-5472.22430149.v1
Autor:
Steven A. Johnsen, Feda H. Hamdan, Elisabeth Hessmann, Christine S Gibhardt, Zeynab Najafova, Jochen Gaedcke, Philipp Ströbel, Ivan Bogeski, Volker Ellenrieder, Waltraut Kopp, Xin Wang, Ana P. Kutschat, Alexander Q. Wixom
Publikováno v:
Cancer Res
Pancreatic ductal adenocarcinoma (PDAC) displays a dismal prognosis due to late diagnosis and high chemoresistance incidence. For advanced disease stages or patients with comorbidities, treatment options are limited to gemcitabine alone or in combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4e97579d8b5e9744bc2d3a0e36615f
https://doi.org/10.1158/0008-5472.can-20-2874
https://doi.org/10.1158/0008-5472.can-20-2874
Autor:
Tanya A. Miura, Benjamin J. Ridenhour, Maricris N. Naranjo, James T. Van Leuven, Alexander Q. Wixom, Emmanuel C. Ijezie, John L. Clary, Andres J. Gonzalez, Craig R. Miller
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
mSphere
mSphere
Coinfection by unrelated viruses in the respiratory tract is common and can result in changes in disease severity compared to infection by individual virus strains. We have previously shown that inoculation of mice with rhinovirus (RV) two days prior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8d5d82119e1208aa0b867111fd55c3
https://journals.asm.org/doi/10.1128/mSphere.00479-21
https://journals.asm.org/doi/10.1128/mSphere.00479-21