Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Alexander Polyzos"'
Autor:
Panagiotis Galanos, George Pappas, Alexander Polyzos, Athanassios Kotsinas, Ioanna Svolaki, Nickolaos N. Giakoumakis, Christina Glytsou, Ioannis S. Pateras, Umakanta Swain, Vassilis L. Souliotis, Alexandros G. Georgakilas, Nicholas Geacintov, Luca Scorrano, Claudia Lukas, Jiri Lukas, Zvi Livneh, Zoi Lygerou, Dipanjan Chowdhury, Claus Storgaard Sørensen, Jiri Bartek, Vassilis G. Gorgoulis
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/beff166f30f240c0acbbef245aa70b71
Autor:
Theodore Sakellaropoulos, Konstantinos Vougas, Sonali Narang, Filippos Koinis, Athanassios Kotsinas, Alexander Polyzos, Tyler J. Moss, Sarina Piha-Paul, Hua Zhou, Eleni Kardala, Eleni Damianidou, Leonidas G. Alexopoulos, Iannis Aifantis, Paul A. Townsend, Mihalis I. Panayiotidis, Petros Sfikakis, Jiri Bartek, Rebecca C. Fitzgerald, Dimitris Thanos, Kenna R. Mills Shaw, Russell Petty, Aristotelis Tsirigos, Vassilis G. Gorgoulis
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3367-3373.e4 (2019)
Summary: A major challenge in cancer treatment is predicting clinical response to anti-cancer drugs on a personalized basis. Using a pharmacogenomics database of 1,001 cancer cell lines, we trained deep neural networks for prediction of drug response
Externí odkaz:
https://doaj.org/article/2f093439d55c431e845ff5db7f56e938
Autor:
Indre Piragyte, Thomas Clapes, Aikaterini Polyzou, Ramon I. Klein Geltink, Stylianos Lefkopoulos, Na Yin, Pierre Cauchy, Jonathan D. Curtis, Lhéanna Klaeylé, Xavier Langa, Cora C. A. Beckmann, Marcin W. Wlodarski, Patrick Müller, Dominic Van Essen, Angelika Rambold, Friedrich G. Kapp, Marina Mione, Joerg M. Buescher, Erika L. Pearce, Alexander Polyzos, Eirini Trompouki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
HLX transcription factor regulates haematopoietic stem and progenitor cell (HSPC) differentiation and is overexpressed in acute myeloid leukemia. Here the authors show that HLX overexpression leads to myeloid differentiation block in zebrafish and hu
Externí odkaz:
https://doaj.org/article/6e1870de09fa401dacacea3d50a2697e
Autor:
Panagiotis Galanos, George Pappas, Alexander Polyzos, Athanassios Kotsinas, Ioanna Svolaki, Nickolaos N. Giakoumakis, Christina Glytsou, Ioannis S. Pateras, Umakanta Swain, Vassilis L. Souliotis, Alexandros G. Georgakilas, Nicholas Geacintov, Luca Scorrano, Claudia Lukas, Jiri Lukas, Zvi Livneh, Zoi Lygerou, Dipanjan Chowdhury, Claus Storgaard Sørensen, Jiri Bartek, Vassilis G. Gorgoulis
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background Genomic instability promotes evolution and heterogeneity of tumors. Unraveling its mechanistic basis is essential for the design of appropriate therapeutic strategies. In a previous study, we reported an unexpected oncogenic prope
Externí odkaz:
https://doaj.org/article/9b0efbdf48a04b4594ca10f1f9e8aefa
Autor:
Eirini-Stavroula Komseli, Ioannis S. Pateras, Thorbjørn Krejsgaard, Konrad Stawiski, Sophia V. Rizou, Alexander Polyzos, Fani-Marlen Roumelioti, Maria Chiourea, Ioanna Mourkioti, Eleni Paparouna, Christos P. Zampetidis, Sentiljana Gumeni, Ioannis P. Trougakos, Dafni-Eleftheria Pefani, Eric O’Neill, Sarantis Gagos, Aristides G. Eliopoulos, Wojciech Fendler, Dipanjan Chowdhury, Jiri Bartek, Vassilis G. Gorgoulis
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-22 (2018)
Abstract Background Senescence is a fundamental biological process implicated in various pathologies, including cancer. Regarding carcinogenesis, senescence signifies, at least in its initial phases, an anti-tumor response that needs to be circumvent
Externí odkaz:
https://doaj.org/article/81dbe18ab5e9469282c85c4909c60800
Autor:
Eirini-Stavroula Komseli, Ioannis S. Pateras, Thorbjørn Krejsgaard, Konrad Stawiski, Sophia V. Rizou, Alexander Polyzos, Fani-Marlen Roumelioti, Maria Chiourea, Ioanna Mourkioti, Eleni Paparouna, Christos P. Zampetidis, Sentiljana Gumeni, Ioannis P. Trougakos, Dafni-Eleftheria Pefani, Eric O’Neill, Sarantis Gagos, Aristides G. Eliopoulos, Wojciech Fendler, Dipanjan Chowdhury, Jiri Bartek, Vassilis G. Gorgoulis
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/11f7dd1fa5de402780e7699c1f5acd06
Autor:
Katerina Gkirtzimanaki, Eleni Kabrani, Dimitra Nikoleri, Alexander Polyzos, Athanasios Blanas, Prodromos Sidiropoulos, Antonis Makrigiannakis, George Bertsias, Dimitrios T. Boumpas, Panayotis Verginis
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 921-933.e5 (2018)
Summary: Interferon α (IFNα) is a prompt and efficient orchestrator of host defense against nucleic acids but upon chronicity becomes a potent mediator of autoimmunity. Sustained IFNα signaling is linked to pathogenesis of systemic lupus erythemat
Externí odkaz:
https://doaj.org/article/89105e9c2150400d8a710d0701303822
Autor:
Matthieu D. Lavigne, Giannis Vatsellas, Alexander Polyzos, Evangelia Mantouvalou, George Sianidis, Ioannis Maraziotis, Marios Agelopoulos, Dimitris Thanos
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1090-1101 (2015)
The histone variant macroH2A (mH2A) has been implicated in transcriptional repression, but the molecular mechanisms that contribute to global mH2A-dependent genome regulation remain elusive. Using chromatin immunoprecipitation sequencing (ChIP-seq) c
Externí odkaz:
https://doaj.org/article/404e19c4f1494355b4b38c66227722c5
Autor:
Kalliopi I Pappa, Alexander Polyzos, Jasmine Jacob-Hirsch, Ninette Amariglio, George D Vlachos, Dimitrios Loutradis, Nicholas P Anagnou
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142229 (2015)
Studies on individual types of gynecological cancers (GCs), utilizing novel expression technologies, have revealed specific pathogenetic patterns and gene markers for cervical (CC), endometrial (EC) and vulvar cancer (VC). Although the clinical pheno
Externí odkaz:
https://doaj.org/article/ec1b8e1c47a5431082a2336d780f6f02
Autor:
Vidur Garg, Yang Yang, Sonja Nowotschin, Manu Setty, Ying-Yi Kuo, Roshan Sharma, Alexander Polyzos, Eralda Salataj, Dylan Murphy, Amy Jang, Dana Pe’er, Effie Apostolou, Anna-Katerina Hadjantonakis
Publikováno v:
bioRxiv
SUMMARYTwo distinct fates, pluripotent epiblast (EPI) and primitive (extra-embryonic) endoderm (PrE), arise from common progenitor cells, the inner cell mass (ICM), in mammalian embryos. To study how these sister identities are forged, we leveraged e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cf4ed600e290e5a885121db877f73d
https://europepmc.org/articles/PMC10081288/
https://europepmc.org/articles/PMC10081288/
