Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexander Pajic"'
Autor:
Maria G. Masucci, Teresa Frisan, Martin S. Staege, Alexander Pajic, Alan B. Rickinson, Georg W. Bornkamm, Josef Mautner, Steven P. Lee, Axel Polack, Siegfried Scholz
Publikováno v:
Proceedings of the National Academy of Sciences. 99:4550-4555
Lymphoblastoid cell lines, generated by immortalization of normal B cells by Epstein–Barr virus (EBV)in vitro, have strong antigen-presenting capacity, are sensitive to EBV-specific cytotoxic T cells, and are highly allostimulatory in mixed lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f260818afcffbf7e1974d244e29ef33c
https://doi.org/10.1073/pnas.072495599
https://doi.org/10.1073/pnas.072495599
Autor:
Barbara Christoph, Franz Kohlhuber, Axel Polack, Dirk Eick, Georg W. Bornkamm, Marino Schuhmacher, Bettina Kempkes, Dimitry Spitkovsky, Martin S. Staege, Markus Brielmeier, Joachim W. Ellwart, Alexander Pajic
Publikováno v:
International Journal of Cancer. 87:787-793
The product of the proto-oncogene c-myc (myc) is a potent activator of cell proliferation. In Burkitt lymphoma (BL), a human B-cell tumor, myc is consistently found to be transcriptionally activated by chromosomal translocation. The mechanisms by whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834e174f5236cc78ce4934257debc74b
https://doi.org/10.1002/1097-0215(20000915)87:6<787::aid-ijc4>3.0.co
https://doi.org/10.1002/1097-0215(20000915)87:6<787::aid-ijc4>3.0.co
Autor:
Alexander Pajic, Dirk Eick, Martin S. Staege, Marino Schuhmacher, Franz Kohlhuber, Georg W. Bornkamm, Axel Polack, Ulrich H. Weidle
Publikováno v:
Current Biology. 9:1255-1258
The c-Myc protein (Myc) is a transcription factor, and deregulated expression of the c-myc gene (myc) is frequently found in tumours. In Burkitt's lymphoma (BL), myc is transcriptionally activated by chromosomal translocation. We have used a B-cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eadd2eddb34e9ea01ea86e2f5f1d329
https://doi.org/10.1016/s0960-9822(99)80507-7
https://doi.org/10.1016/s0960-9822(99)80507-7
Publikováno v:
FEBS Lett
Incompletely synthesized polypeptides in the mitochondrial inner membrane are subject to rapid proteolysis. We demonstrate that Yta10p, a mitochondrial homologue of a conserved family of putative ATPases in Saccharomyces cerevisiae, is essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b32824ee4b75ff3e4104bd695a79111
https://doi.org/10.1016/0014-5793(94)01046-3
https://doi.org/10.1016/0014-5793(94)01046-3
Autor:
Georg W. Bornkamm, Barbara Baier, Alexander Pajic, Dimitry Spitkovsky, Martin S. Staege, Axel Polack, Gerhard Laux
Publikováno v:
The Journal of general virology. 82(Pt 12)
Epstein–Barr virus (EBV) transforms primary B cells in vitro. Established cell lines adopt a lymphoblastoid phenotype (LCL). In contrast, EBV-positive Burkitt’s lymphoma (BL) cells, in which the proto-oncogene c-myc is constitutively activated, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ee6f32d5f38c7664595c49d2715e27
https://pubmed.ncbi.nlm.nih.gov/11714983
https://pubmed.ncbi.nlm.nih.gov/11714983
Autor:
Diana Dudziak, Georg W. Bornkamm, Axel Polack, Marino Schuhmacher, Martin S. Staege, Markus Brielmeier, Dimitri Spitkovsky, Günther Eissner, Alexander Pajic
Publikováno v:
International journal of cancer. 93(6)
Epstein-Barr virus (EBV) immortalized cells and Burkitt lymphoma cells have a completely different growth pattern and phenotype. EBV immortalized cells express a set of 11 viral genes to accommodate B cell activation and proliferation, whereas EBV-po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586c4087aa8159865839bf716869b118
https://pubmed.ncbi.nlm.nih.gov/11519042
https://pubmed.ncbi.nlm.nih.gov/11519042
Autor:
Axel Polack, Alexander Pajic, Bettina Kempkes, Barbara Baier, C Geltinger, Josef Mautner, K. Hörtnagel, Georg W. Bornkamm, M. Falk, Barbara Christoph
Two genetic events contribute to the development of endemic Burkitt lymphoma (BL) infection of B lymphocytes with Epstein-Barr virus (EBV) and the activation of the protooncogene c-myc through chromosomal translocation. The viral genes EBV nuclear an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0a009d8ddf9a9cdae211c13266c26e
https://europepmc.org/articles/PMC38398/
https://europepmc.org/articles/PMC38398/
Publisher Summary This chapter discusses the experimental procedures for studying this proteolytic breakdown that might represent a useful model system to understand the degradation of membrane-associated polypeptides. The analysis of this process in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e568b80c49e226079e266b4d2a0bf4bd
https://doi.org/10.1016/0076-6879(95)60161-9
https://doi.org/10.1016/0076-6879(95)60161-9
Autor:
Thomas Langer, Gertrud Mannhaupt, Reimund Tauer, Ralf Schnall, Alexander Pajic, Horst Feldmann
Publikováno v:
FEBS Lett
The yeast gene, YTA10, encodes a member of a novel family of putative ATPases. Yta10p, as deduced from the nucleotide sequence, is 761 amino acids in length (predicted molecular mass 84.5 kDa). The amino acid sequence of Yta10p exhibits high similari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a99c571d7d0f64a4f4306d03e8fc5c5
https://hdl.handle.net/21.11116/0000-000B-6E5C-4
https://hdl.handle.net/21.11116/0000-000B-6E5C-4
Antagonistic effects of c-myc and Epstein-Barr virus latent genes on the phenotype of human B cells.
Autor:
Pajic, Alexander, Staege, Martin S., Dudziak, Diana, Schuhmacher, Marino, Spitkovsky, Dimitri, Eissner, Günther, Brielmeier, Markus, Polack, Axel, Bornkamm, Georg W.
Publikováno v:
International Journal of Cancer; Sep2001, Vol. 93 Issue 6, p810-816, 7p