Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alexander P, Hynes"'
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT A recent demonstration of synergy between a temperate phage and the antibiotic ciprofloxacin suggested a scalable approach to exploiting temperate phages in therapy, termed temperate phage-antibiotic synergy, which specifically interacted wi
Externí odkaz:
https://doaj.org/article/f800b55c5cfe47f08f94b2716dc78026
Publikováno v:
Viruses, Vol 15, Iss 1, p 25 (2022)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/3c88b40709a94d2b80d9fd5b6d08609b
Autor:
Kevin Champagne-Jorgensen, Tamina A. Jose, Andrew M. Stanisz, M. Firoz Mian, Alexander P. Hynes, John Bienenstock
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Gut microbiota have myriad roles in host physiology, development, and immunity. Though confined to the intestinal lumen by the epithelia, microbes influence distal systems via poorly characterized mechanisms. Recent work has considered the role of ex
Externí odkaz:
https://doaj.org/article/650981570e584d369154d625f86e52bc
Autor:
Alexander P. Hynes, Geneviève M. Rousseau, Daniel Agudelo, Adeline Goulet, Beatrice Amigues, Jeremy Loehr, Dennis A. Romero, Christophe Fremaux, Philippe Horvath, Yannick Doyon, Christian Cambillau, Sylvain Moineau
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Some phages carry genes coding for anti-CRISPR (Acr) proteins that interfere with the activity of bacterial CRISPR-Cas systems. Here, Hynes et al. characterize a new Acr family from streptococcal phages and investigate its potential in genome-editing
Externí odkaz:
https://doaj.org/article/2c460a63a313487ab66f065d9084faaf
Autor:
Janeth Gomez-Garcia, Alejandra Chavez-Carbajal, Nallelyt Segundo-Arizmendi, Miriam G. Baron-Pichardo, Susana E. Mendoza-Elvira, Efren Hernandez-Baltazar, Alexander P. Hynes, Oscar Torres-Angeles
Publikováno v:
Viruses, Vol 13, Iss 10, p 1932 (2021)
Modern bacteriophage encapsulation methods based on polymers such as alginate have been developed recently for their use in phage therapy for veterinary purposes. In birds, it has been proven that using this delivery system allows the release of the
Externí odkaz:
https://doaj.org/article/842a8541a09244e3b2aabe2e5134ca7c
Publikováno v:
Viruses, Vol 13, Iss 3, p 455 (2021)
Many bacteria carry bacteriophages (bacterial viruses) integrated in their genomes in the form of prophages, which replicate passively alongside their bacterial host. Environmental conditions can lead to prophage induction; the switching from prophag
Externí odkaz:
https://doaj.org/article/be3d03dbb1174d29881dfd6bf23ad096
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
ABSTRACT The adaptive immune system of prokaryotes, called CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated genes), results in specific cleavage of invading nucleic acid sequences recognized by the cell’s
Externí odkaz:
https://doaj.org/article/e5ed4ae1150b4e7380f5f66b791592ca
Autor:
Janeth, Gomez-Garcia, Alejandra, Chavez-Carbajal, Nallelyt, Segundo-Arizmendi, Miriam G, Baron-Pichardo, Susana E, Mendoza-Elvira, Efren, Hernandez-Baltazar, Alexander P, Hynes, Oscar, Torres-Angeles
Publikováno v:
Viruses
Modern bacteriophage encapsulation methods based on polymers such as alginate have been developed recently for their use in phage therapy for veterinary purposes. In birds, it has been proven that using this delivery system allows the release of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07498577f989d52f7773d53191bd8d3f
https://pubmed.ncbi.nlm.nih.gov/34696362
https://pubmed.ncbi.nlm.nih.gov/34696362
Autor:
M. Firoz Mian, Alexander P. Hynes, Tamina A. Jose, Andrew M. Stanisz, Kevin Champagne-Jorgensen, John Bienenstock
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Gut microbiota have myriad roles in host physiology, development, and immunity. Though confined to the intestinal lumen by the epithelia, microbes influence distal systems via poorly characterized mechanisms. Recent work has considered the role of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a17e0776ea8d3e32d3854731a171b7
https://doaj.org/article/650981570e584d369154d625f86e52bc
https://doaj.org/article/650981570e584d369154d625f86e52bc
Publikováno v:
Cell reports. 35(8)
Mounting stress from multidrug-resistant bacteria has renewed interest in bacteriophage (bacterial virus, phage) therapy as an alternative to antibiotics. While virulent phages quickly infect and kill their host through a lytic lifecycle, temperate p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812d74a4bbeef00cc19ecbd368bc7b9f
https://pubmed.ncbi.nlm.nih.gov/34038739
https://pubmed.ncbi.nlm.nih.gov/34038739