Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alexander N Trofimov"'
Autor:
Alexander P Schwarz, Veronika A Nikitina, Darya U Krytskaya, Ksenia P Shcherbakova, Alexander N Trofimov
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0273224 (2023)
Reverse transcription followed by quantitative (real-time) polymerase chain reaction (RT-qPCR) has become the gold standard in mRNA expression analysis. However, it requires an accurate choice of reference genes for adequate normalization. The aim of
Externí odkaz:
https://doaj.org/article/959854423b2e48b7ac3c6c51c262cc7c
Autor:
Maria V. Litvinova, Alexander N. Trofimov, Petr D. Shabanov, Andrei A. Lebedev, Evgeny R. Bychkov, Nikolay А. Arseniev, Alexander I. Tyukavin
Publikováno v:
Pharmacy Formulas. 4:82-96
One of the unresolved problems on the way to improving the pharmacotherapy of CNS diseases is the development and creation of technologies that allow drugs to cross the blood-brain barrier (BBB). The review discusses modern methods of drug delivery t
Autor:
Alexander N. Trofimov, Mariya V. Litvinova, Alexander P. Schwarz, Vera V. Kosheverova, Andrei A. Lebedev, Nikolay А. Arseniev, Aleksandr I. Tyukavin
Publikováno v:
Pharmacy Formulas.
Biological barriers play a key role in maintaining the integrity and functioning of the body at all levels of its organization. The barrier function at the cellular level is based on the hydrophobic properties of the cytoplasmic membrane, which provi
Autor:
O. E. Zubareva, A. Yu. Rotov, Alexander P. Schwarz, Ekaterina Veniaminova, K. Fomalont, Alexander N. Trofimov
Publikováno v:
Neuroscience and Behavioral Physiology. 50:1239-1248
Many studies have shown that early experience, particularly of neonatal infections, has a role in forming high anxiety levels in later life. One of the mechanisms of these changes may consist of impairments to the functional activity of ionotropic gl
Autor:
Darya Krytskaya, Alexander N. Trofimov, Ksenia Shcherbakova, Alexander P. Schwarz, Veronika Nikitina
RT-qPCR has become the gold standard in mRNA expression analysis. However, it requires an accurate choice of reference genes for adequate normalization. This work aims to validate the reference genes for qPCR experiments in the brain of rats in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e41a1c29ca4babf5b2be95b1d6eaac30
https://doi.org/10.21203/rs.3.rs-851204/v1
https://doi.org/10.21203/rs.3.rs-851204/v1
Autor:
Alexander N. Trofimov, Maria V Zakharova, Veronika Nikitina, Alexander P. Schwarz, Gleb V Beznin, Olga E. Zubareva, Sergei G Tsikunov
Publikováno v:
Biochemistry. Biokhimiia. 86(6)
According to the two-hit hypothesis of psychoneuropathology formation, infectious diseases and other pathological conditions occurring during the critical periods of early ontogenesis disrupt normal brain development and increase its susceptibility t
Autor:
Alexander N. Trofimov, Irina Ivleva, Darya Krytskaya, Sergey A. Apryatin, Marina N. Karpenko, Veronika Nikitina, Alexander P. Schwarz, Ksenia Shcherbakova
Publikováno v:
NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY.
Publikováno v:
Medical academic journal. 19:109-111
Various detrimental factors during early life may affect CNS development and increase risk of neuropsychiatric symptoms in later life. Disruption in brain dopaminergic system maturation is believed to be one of the mechanism of different neurodevelop
Autor:
Olga I. Chuprina, Alexander M. Ischenko, Darya Krytskaya, Vera V. Kosheverova, Alexander N. Trofimov, Alexander Yu. Rotov, O. E. Zubareva, Alexander P. Schwarz
Publikováno v:
Neurobiology of Learning and Memory. 155:231-238
Long (D2L) and Short (D2S) isoforms of D2 dopamine receptor differ in their biochemical and physiological properties, which could affect functioning of prefrontal cortex. Contribution of distinct D2 dopamine receptor isoforms to cognitive dysfunction
Autor:
Alexander P. Schwarz, Victoria Lioudyno, O. E. Zubareva, V. M. Klimenko, Alexander N. Trofimov, Vera V. Kosheverova, Alexander M. Ischenko
Publikováno v:
Behavioural Brain Research. 333:118-122
Long (D2L) and short (D2S) isoform of the D2 dopamine receptor are believed to play different roles in behavioral regulation. However, little is known about differential regulation of these isoforms mRNA expression during the process of learning in p