Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alexander N, Wein"'
Autor:
Benjamin G. Barwick, Christopher D. Scharer, Ryan J. Martinez, Madeline J. Price, Alexander N. Wein, Robert R. Haines, Alexander P. R. Bally, Jacob E. Kohlmeier, Jeremy M. Boss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
DNA methylation is known to contribute to B cell differentiation, but de novo methylation has not been studied in this context. Here the authors use a conditional Dnmt3a/b knockout mouse to map the function of de novo DNA methylation in B cell differ
Externí odkaz:
https://doaj.org/article/33af14121bb04d5cbdd45624b424b0e7
Autor:
Cliona O'Farrelly, Brian W. Wong, Min Xu, Ola Ahmed, Yiing Lin, Alexander N Wein, Fangyu Zhou, William C. Chapman, Gundumi A. Upadhya, Li Ye
Publikováno v:
American Journal of Transplantation. 22:58-70
Antioxidant defence mechanisms, such as the nuclear factor-erythroid 2-related-factor-2 (NRF2) axis, are integral to oxidative stress responses and ischemic injury. Hepatic antioxidant capacity is contingent on parenchymal quality, and there is a nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d609272c1481e899ac2fa526565ec9
https://doi.org/10.1111/ajt.16789
https://doi.org/10.1111/ajt.16789
Autor:
Alison Swaims-Kohlmeier, Alexander N. Wein, Felica P. Hardnett, Anandi N. Sheth, Zheng-Rong Tiger Li, M. Elliot Williams, Jessica Radzio-Basu, HaoQiang Zheng, Chuong Dinh, Lisa B. Haddad, Elizabeth M.B. Collins, Jenna L. Lobby, Kirsten Kost, Sarah L. Hayward, Igho Ofotokun, Rustom Antia, Christopher D. Scharer, Anice C. Lowen, J. Gerardo Garcia-Lerma, Jacob E. Kohlmeier
Despite their importance for immunity against sexually transmitted infections (STIs), the composition of the female reproductive tract (FRT) memory CD4 T cell population in response to changes in the local tissue environment during the menstrual cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86e42516ff915ae2e2ddcbe8251df1c
https://doi.org/10.1101/2022.10.01.510445
https://doi.org/10.1101/2022.10.01.510445
Autor:
Ida E M Uddbäck, Sarah L. Hayward, Alexander N. Wein, Jenna L. Lobby, Allan Randrup Thomsen, Emily K. Cartwright, Jacob E. Kohlmeier, Shiki Takamura, Jan Pravsgaard Christensen, Amalie Skak Schøller
Publikováno v:
Mucosal immunology
Tissue resident memory T cells (TRM) in the lungs are pivotal for protection against repeated infection with respiratory viruses. However, the gradual loss of these cells over time and the associated decline in clinical protection represent a serious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e744585489338b8105651011adccd8
http://europepmc.org/articles/PMC7726002
http://europepmc.org/articles/PMC7726002
Autor:
Shiki Takamura, Nivedha Kumar, Alexander N. Wein, Sarah L. Hayward, Jacob E. Kohlmeier, Tetsuo Tsukamoto, Zheng-Rong Tiger Li, Paul Dunbar, Satoshi Ueha, Emily K. Cartwright, Ida E M Uddbäck
Publikováno v:
Mucosal Immunology. 13:161-171
Lung resident memory CD8 T cells (TRM) are critical for protection against respiratory viruses, but the cellular interactions required for their development are poorly understood. Herein we describe the necessity of classical monocytes for the establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75370c0755be6c8f3cac6251872e9337
https://doi.org/10.1038/s41385-019-0224-7
https://doi.org/10.1038/s41385-019-0224-7
Publikováno v:
Transplant infectious disease : an official journal of the Transplantation Society. 24(3)
Previous reports of coronavirus disease 2019 (COVID-19) following lung transplantation generally described a grim prognosis, but these were anecdotal case series of symptomatic patients. A systematic study of the outcomes and pathology of SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425cc7fd426081ad77a37e69ab105dd8
https://pubmed.ncbi.nlm.nih.gov/35279033
https://pubmed.ncbi.nlm.nih.gov/35279033
Publikováno v:
BMJ Case Reports
Since identified in December 2019, COVID-19 has remained a pandemic across the globe. Although primarily a respiratory illness, the impact of COVID-19 on other end organs has been increasingly identified. The effect of COVID-19 on the liver has yet t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3265c4603aa96e98a9d0b3d8730c8a91
https://pubmed.ncbi.nlm.nih.gov/34446515
https://pubmed.ncbi.nlm.nih.gov/34446515
Autor:
Chao Gao, Jenna L. Lobby, Nan Jia, Alexander N. Wein, Yasuyuki Matsumoto, Jacob E. Kohlmeier, Lauren Byrd-Leotis, Richard D. Cummings, David A. Steinhauer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Glycans within human lungs are recognized by many pathogens such as influenza A virus (IAV), yet little is known about their structures. Here we present the first analysis of the N- and O- and glycosphingolipid-glycans from total human lungs, along w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118b664d9fd7e94e1dd2f4ad0812e84f
https://doi.org/10.1038/s41598-020-62074-z
https://doi.org/10.1038/s41598-020-62074-z
Autor:
Paul Dunbar, Jacob E. Kohlmeier, Sean R. McMaster, Alexander N. Wein, Timothy L. Denning, Zheng-Rong Tiger Li
Publikováno v:
The Journal of Immunology. 201:573-582
Although influenza virus infection remains a concerning disease for public health, the roles of individual cytokines during the immune response to influenza infection are not fully understood. We have identified IL-36γ as a key mediator of immune pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a383a9180059279756f9550256754046
https://doi.org/10.4049/jimmunol.1701796
https://doi.org/10.4049/jimmunol.1701796