Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alexander Murison"'
Autor:
Aneta Mikulasova, Christopher P. Wardell, Alexander Murison, Eileen M. Boyle, Graham H. Jackson, Jan Smetana, Zuzana Kufova, Ludek Pour, Viera Sandecka, Martina Almasi, Pavla Vsianska, Evzen Gregora, Petr Kuglik, Roman Hajek, Faith E. Davies, Gareth J. Morgan, Brian A. Walker
Publikováno v:
Haematologica, Vol 102, Iss 9 (2017)
Monoclonal gammopathy of undetermined significance is a pre-malignant precursor of multiple myeloma with a 1% risk of progression per year. Although targeted analyses have shown the presence of specific genetic abnormalities such as IGH translocation
Externí odkaz:
https://doaj.org/article/b9c9544af99e4b429a5b86e568baa315
Autor:
Fabio Mirabella, Alexander Murison, Lauren I Aronson, Christopher P Wardell, Andrew J Thompson, Sarah J Hanrahan, Jacqueline H L Fok, Charlotte Pawlyn, Martin F Kaiser, Brian A Walker, Faith E Davies, Gareth J Morgan
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99493 (2014)
The chromosomal translocation t(4;14) deregulates MMSET (WHSC1/NSD2) expression and is a poor prognostic factor in multiple myeloma (MM). MMSET encodes two major protein isoforms. We have characterized the role of the shorter isoform (REIIBP) in myel
Externí odkaz:
https://doaj.org/article/800512e40ad7484aa213d1a499a54ad7
Autor:
Sarina Cameron, Genevieve Deblois, James R. Hawley, Aditi Qamra, Stanley Zhou, Seyed Ali Madani Tonekaboni, Alexander Murison, Romy Van Vliet, Juan Liu, Jason W. Locasale, Mathieu Lupien
Publikováno v:
Oncogene. 42:1693-1703
Predicting and treating recurrence in intermediate-risk prostate cancer patients remains a challenge despite having identified genomic instability (1) and hypoxia (2,3) as risk factors. This underlies challenges in assigning the functional impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2803f18612eb112dc5b2a18fbf540701
https://doi.org/10.1038/s41388-023-02680-z
https://doi.org/10.1038/s41388-023-02680-z
Autor:
Andy G.X. Zeng, Murtaza S Nagree, Alexander Murison, Isabel Lim, Sayyam Shah, Alicia Aguilar-Navarro, Joana Araújo, Darrien Parris, Jessica L McLeod, Liqing Jin, Elvin Wagenblast, Eugenia Flores-Figueroa, John E. Dick, Stephanie Z Xie
Publikováno v:
Blood. 140:2218-2219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3603c0073859b00cc1783e372f6c8c76
https://doi.org/10.1182/blood-2022-170303
https://doi.org/10.1182/blood-2022-170303
Autor:
Veronique Voisin, Erwin M. Schoof, Eric R. Lechman, Nathan Mbong, Andy G.X. Zeng, James A. Kennedy, Daniel D. De Carvalho, Gabriela Krivdova, Olga I. Gan, Gene W. Yeo, Leonardo Salmena, Gary D. Bader, John E. Dick, Elvin Wagenblast, Martino Gabra, Eric L. Van Nostrand, Mark D. Minden, Alexander Murison, Brian A. Yee, Stefan Aigner, Jessica McLeod, Sajid A. Marhon, Karin G. Hermans, Alexander A. Shishkin, Aaron Trotman-Grant
SUMMARYGene expression profiling and proteome analysis of normal and malignant hematopoietic stem cells (HSC) point to shared core stemness properties. However, discordance between mRNA and protein signatures underscores an important role for post-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8e3b525e4acdf9d20d00d19dc43385d
https://doi.org/10.1101/2021.07.30.454489
https://doi.org/10.1101/2021.07.30.454489
Autor:
Stephanie Xie, Murtaza Nagree, Andy Zeng, Alexander Murison, Joana Araújo, Isabel Lim, Darrien Parris, Jessica McLeod, Liqing Jin, Elvin Wagenblast, john Dick
Publikováno v:
Experimental Hematology. 111:S160-S161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe05854cc3dd41afb5e8fb3990059571
https://doi.org/10.1016/j.exphem.2022.07.288
https://doi.org/10.1016/j.exphem.2022.07.288
Autor:
Graham Jackson, Martina Almáši, Pavla Všianská, Christopher P. Wardell, Faith E. Davies, Brian A Walker, Gareth J. Morgan, Roman Hájek, Eileen M Boyle, Zuzana Kufova, Viera Sandecká, Jan Smetana, Petr Kuglík, Alexander Murison, Aneta Mikulasova, Evzen Gregora, Ludek Pour
Publikováno v:
Haematologica
Monoclonal gammopathy of undetermined significance is a pre-malignant precursor of multiple myeloma with a 1% risk of progression per year. Although targeted analyses have shown the presence of specific genetic abnormalities such as IGH translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b34b2317b304d598e16a2922d2cfa97
http://europepmc.org/articles/PMC5685224
http://europepmc.org/articles/PMC5685224
Autor:
Simon, Scofield, Alexander, Murison, Angharad, Jones, John, Fozard, Mitsuhiro, Aida, Leah R, Band, Malcolm, Bennett, James A H, Murray
Publikováno v:
Development (Cambridge, England). 145(9)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4ba93f8d0a2aa94674e645c35b5cd28
https://pubmed.ncbi.nlm.nih.gov/29650590
https://pubmed.ncbi.nlm.nih.gov/29650590
Autor:
Robert G. Bristow, Theodorus van der Kwast, Ken Kron, Stanley Zhou, Vincent Huang, Michael Fraser, Mathieu Lupien, Takafumi N. Yamaguchi, Yu Jia Shiah, Paul C. Boutros, Alexander Murison
Publikováno v:
Nature genetics. 49(9)
TMPRSS2-ERG (T2E) structural rearrangements typify ∼50% of prostate tumors and result in overexpression of the ERG transcription factor. Using chromatin, genomic and expression data, we show distinct cis-regulatory landscapes between T2E-positive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a870025b70873e0293fbb8cd854a050
https://pubmed.ncbi.nlm.nih.gov/29129399
https://pubmed.ncbi.nlm.nih.gov/29129399
Autor:
Michèle Orain, Yu Jia Shiah, Ken Kron, Lawrence E. Heisler, Mathieu Lupien, Xuemei Luo, Andre P. Masella, Michelle Sam, Paul C. Boutros, Shaylan K. Govind, Daryl Waggott, Veronica Y. Sabelnykova, Natalie S. Fox, Musaddeque Ahmed, Julia F. Hopkins, Lee Timms, Clement Fung, Francis Nguyen, Zhiyuan Wang, Taryne Chong, Alain Bergeron, Julie Livingstone, Yves Fradet, Melvin L.K. Chua, Timothy Beck, Alexander Murison, Bernard Têtu, Ada Wong, Ren X. Sun, Constance H. Li, Kathleen E. Houlahan, John Douglas Mcpherson, Cenk Sahinalp, Housheng Hansen He, Junyan Zhang, Robert G. Bristow, Jeremy Johns, Neil E. Fleshner, Alejandro Berlin, Michelle Chan-Seng-Yue, Christine P'ng, Nicholas Buchner, Alister D'Costa, Richard de Borja, Xihui Lin, Louis Lacombe, Jeffrey Green, Hélène Hovington, Vincent Huang, Kenneth C. Chu, Haiying Kong, Emilie Lalonde, Nicholas J. Harding, Syed Haider, Esther Jung, Colin Collins, Shadrielle Melijah G. Espiritu, Takafumi N. Yamaguchi, Bryan Lo, Michael Xie, Valérie Picard, Michael Fraser, Stephenie D. Prokopec, Christopher I Cooper, Fouad Yousif, Theodorus van der Kwast, Robert E. Denroche, Alice Meng, Dominique Trudel, Alan Dal Pra
Prostate tumours are highly variable in their response to therapies, but clinically available prognostic factors can explain only a fraction of this heterogeneity. Here we analysed 200 whole-genome sequences and 277 additional whole-exome sequences f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c6c8d0a7ff285be2d7353f137a1e56