Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexander Moscu‐Gregor"'
Autor:
Yingrui Li, Hendrik Dinkel, Dalia Pakalniskyte, Alexandra Viktoria Busley, Lukas Cyganek, Rujia Zhong, Feng Zhang, Qiang Xu, Lasse Maywald, Assem Aweimer, Mengying Huang, Zhenxing Liao, Zenghui Meng, Chen Yan, Timo Prädel, Lena Rose, Alexander Moscu‐Gregor, Alyssa Hohn, Zhen Yang, Lin Qiao, Andreas Mügge, Xiaobo Zhou, Ibrahim Akin, Ibrahim El‐Battrawy
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 3, Pp n/a-n/a (2023)
Abstract Background Brugada syndrome (BrS) is causing sudden cardiac death (SCD) mainly at young age. Studying the underlying mechanisms associated with BrS type I electrocardiogram (ECG) changes in the presence of fever and roles of autophagy for Br
Externí odkaz:
https://doaj.org/article/c96503a7f7184eef92bef287fc6cc881
Autor:
Dominik S. Westphal, Tobias Burkard, Alexander Moscu‐Gregor, Roman Gebauer, Gabriele Hessling, Cordula M. Wolf
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Genes encoding cardiac ion channels or regulating proteins have been associated with the inherited form of long QT syndrome (LQTS). Complex pathophysiology and missing functional studies, however, often bedevil variant interpretat
Externí odkaz:
https://doaj.org/article/bea25f40d7734b32b2036bf1a9bb5831
Autor:
Ibrahim El-Battrawy, Jonas Müller, Zhihan Zhao, Lukas Cyganek, Rujia Zhong, Feng Zhang, Mandy Kleinsorge, Huan Lan, Xin Li, Qiang Xu, Mengying Huang, Zhenxing Liao, Alexander Moscu-Gregor, Sebastian Albers, Hendrik Dinkel, Siegfried Lang, Sebastian Diecke, Wolfram-Hubertus Zimmermann, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiaobo Zhou, Ibrahim Akin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
BackgroundAmong rare channelopathies BrS patients are at high risk of sudden cardiac death (SCD). SCN5A mutations are found in a quarter of patients. Other rare gene mutations including SCN1B have been implicated to BrS. Studying the human cellular p
Externí odkaz:
https://doaj.org/article/e4d847f1203f41bca3784f5844070f87
Autor:
Yingrui Li, Lena Rose, Timo Prädel, Mandy Kleinsorge, Xuehui Fan, Zhenxing Liao, Hendrik Dinkel, Alexandra Viktoria Busley, Rujia Zhong, Feng Zhang, Qiang Xu, Lasse Maywald, Assem Aweimer, Mengying Huang, Alexander Moscu-Gregor, Nazha Hamdani, Alyssa Hohn, Zhen Yang, Lin Qiao, Andreas Mügge, Lukas Cyganek, Xiaobo Zhou, Ibrahim Akin, Ibrahim PD. Dr. El-Battrawy
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f258d81a5ec9c02045d2c832bab12a28
https://doi.org/10.2139/ssrn.4316865
https://doi.org/10.2139/ssrn.4316865
Publikováno v:
Medizinische Genetik. 31:222-229
Zusammenfassung Die „Next-generation Sequencing (NGS)“-Technologie ermöglicht es, alle bekannten LQTS-Gene in der Diagnostik parallel zu analysieren. Dies führt dazu, dass in zunehmendem Maße Varianten nachgewiesen werden, deren klinische Bede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cc32251d728b8951668e20d60df967f
https://doi.org/10.1007/s11825-019-0243-5
https://doi.org/10.1007/s11825-019-0243-5
Autor:
Cordula M Wolf, Alexander Moscu‐Gregor, Roman Gebauer, Tobias Burkard, Dominik S. Westphal, Gabriele Hessling
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Background Genes encoding cardiac ion channels or regulating proteins have been associated with the inherited form of long QT syndrome (LQTS). Complex pathophysiology and missing functional studies, however, often bedevil variant interpretation and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9368fcec0b8029db16928c059af03a7a
https://doi.org/10.1055/s-0040-1705528
https://doi.org/10.1055/s-0040-1705528
Autor:
Thomas Paul, Ulrich Krause, Imma Rost, Christoph Marschall, Claus-Eric Ott, Leif-Hendrik Boldt, Carsten Müntjes, Anja Bennewiz, Anne Schönecker, Alexander Moscu-Gregor, Abdul Shokor Parwani, Franziska Schuessler‐Hahn, Felix Hohendanner
Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by adrenergically stimulated ventricular tachycardia. The most common form of CPVT is due to autosomal dominant variants in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a723f8e6339fd01ffb16c4c54d0cbab
https://www.ncbi.nlm.nih.gov/pubmed/32173957
https://www.ncbi.nlm.nih.gov/pubmed/32173957
Background: Arrhythmogenic disorders occur in a broad spectrum of cardiac pathologies in the general population with a prevalence of 1:10,000 to 1:500. Genetic studies conducted during the past 20 years have markedly illuminated the genetic basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c502bb01c2d11309769d31eefdb729
https://europepmc.org/articles/PMC6837920/
https://europepmc.org/articles/PMC6837920/
Autor:
Brigitte Marian, Lisa Nika, Alexander Moscu-Gregor, Christiane Maier, Julia Kostka, Waltraud C. Schrottmaier, Daniela Huber, Jakob Paur, Petra Heffeter, Klaus Holzmann, Thomas Mohr, Sonja Kappel, Walter Berger, Daniela Kandioler, Michael Grusch, Bettina Grasl-Kraupp
Publikováno v:
Hepatology (Baltimore, Md.). 62(6)
Fibroblast growth factor receptors (FGFRs) are frequently up-regulated in subsets of hepatocellular carcinoma (HCC). Here, we provide mechanistic insight that FGFR3 splice variants IIIb and IIIc impact considerably on the malignant phenotype of HCC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5a529e7bc14d63428bb08bef6f47eb
https://pubmed.ncbi.nlm.nih.gov/26235436
https://pubmed.ncbi.nlm.nih.gov/26235436