Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexander Mehlich"'
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
De-novo designed proteins have received wide interest as potential platforms for nano-engineering and biomedicine. While much work is being done in the design of thermodynamically stable proteins, the folding process of artificially designed proteins
Externí odkaz:
https://doaj.org/article/841f0a736ce34a8b935c26b8491e2144
Autor:
Anna-Lena Cost, Alexander Mehlich, Benedikt Sabass, Matthias Rief, Pia Ringer, Andreas Weißl, Carsten Grashoff, Andrea Freikamp, Marc Tramier
Publikováno v:
Nature Methods
Nature Methods, Nature Publishing Group, 2017, 14 (11), pp.1090-1096. ⟨10.1038/nmeth.4431⟩
Nature Methods, 2017, 14 (11), pp.1090-1096. ⟨10.1038/nmeth.4431⟩
Nature Methods, Nature Publishing Group, 2017, 14 (11), pp.1090-1096. ⟨10.1038/nmeth.4431⟩
Nature Methods, 2017, 14 (11), pp.1090-1096. ⟨10.1038/nmeth.4431⟩
International audience; Förster resonance energy transfer (FRET)-based tension sensor modules (TSMs) are available for investigating how distinct proteins bear mechanical forces in cells. Yet, forces in the single piconewton (pN) regime remain diffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0c6c35aa443412bd174a55a9e9d182
https://doi.org/10.1038/nmeth.4431
https://doi.org/10.1038/nmeth.4431
Autor:
Anna Chrostek-Grashoff, C. Klingner, Carsten Grashoff, Alexander Mehlich, Roy Zent, K F Austen, Benedikt Sabass, Carleen Kluger, Pia Ringer, Matthias Rief
Publikováno v:
Nature Cell Biology. 17:1597-1606
The ability of cells to adhere and sense differences in tissue stiffness is crucial for organ development and function. The central mechanisms by which adherent cells detect extracellular matrix compliance, however, are still unknown. Using two singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8293002f47d9faee43da9ed7d2972cb7
https://doi.org/10.1038/ncb3268
https://doi.org/10.1038/ncb3268
Publikováno v:
SI
Journal of Structural Biology
Journal of Structural Biology
The ability of cells to sense and respond to mechanical forces is crucial for a wide range of developmental and pathophysiological processes. The molecular mechanisms underlying cellular mechanotransduction, however, are largely unknown because suita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b7e3d19f835d9fc9e9be094ce21803
https://hdl.handle.net/11858/00-001M-0000-002C-A0FE-1
https://hdl.handle.net/11858/00-001M-0000-002C-A0FE-1
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af914afcda1eac45105b943c89015c61
https://doi.org/10.1038/protex.2015.095
https://doi.org/10.1038/protex.2015.095
Publikováno v:
The Review of scientific instruments. 83(9)
The thermal fluctuations of micron-sized beads in dual trap optical tweezer experiments contain complete dynamic information about the viscoelastic properties of the embedding medium and—if present—macromolecular constructs connecting the two bea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9ff1b8c942a50b5d592fe3fd485293
https://pubmed.ncbi.nlm.nih.gov/23020428
https://pubmed.ncbi.nlm.nih.gov/23020428
Publikováno v:
Thin Solid Films
Thin Solid Films, Elsevier, 2010, 518 (21), pp.6052-6054. ⟨10.1016/j.tsf.2010.06.049⟩
Thin Solid Films, Elsevier, 2010, 518 (21), pp.6052-6054. ⟨10.1016/j.tsf.2010.06.049⟩
International audience; For adhesion measurements, the superlayer method has recently been developed an overlayer under high compressive stress provides the loading and drives interface delamination. We combined the superlayer method with thickness g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fa06fe61703dd1d85af938ede2e3a8
https://hal.archives-ouvertes.fr/hal-00533225
https://hal.archives-ouvertes.fr/hal-00533225