Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Alexander Marin"'
Autor:
Michael Lueckheide, Alexander Marin, Harichandra D. Tagad, Nicholas D. Posey, Vivek M. Prabhu, Alexander K. Andrianov
Publikováno v:
ACS Polymers Au, Vol 3, Iss 5, Pp 354-364 (2023)
Externí odkaz:
https://doaj.org/article/fcf830e7e8d74e9db4c6f48aa6e91a38
Autor:
Sarah M. Valencia, Athina Zacharia, Alexander Marin, Rebecca L. Matthews, Chia-Kuei Wu, Breana Myers, Chelsea Sanders, Simone Difilippantonio, Reinhard Kirnbauer, Richard B. Roden, Ligia A. Pinto, Robert H. Shoemaker, Alexander K. Andrianov, Jason D. Marshall
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 8, Pp 2748-2761 (2021)
Current human papillomavirus (HPV) vaccines provide substantial protection against the most common HPV types responsible for oral and anogenital cancers, but many circulating cancer-causing types remain for which vaccine coverage is lacking. In addit
Externí odkaz:
https://doaj.org/article/da65fc9e002b4c96bf1c802105da3c14
Autor:
Harichandra D. Tagad, Alexander Marin, Ruixue Wang, Abdul S. Yunus, Thomas R. Fuerst, Alexander K. Andrianov
Publikováno v:
Molecules, Vol 28, Iss 10, p 4218 (2023)
The inclusion of fluorine motifs in drugs and drug delivery systems is an established tool for modulating their biological potency. Fluorination can improve drug specificity or boost the vehicle’s ability to cross cellular membranes. However, the a
Externí odkaz:
https://doaj.org/article/c1bba17057a84218a9ce32a36ced909b
Autor:
Andrey Romanyuk, Ruixue Wang, Alexander Marin, Benjamin M. Janus, Eric I. Felner, Dengning Xia, Yenny Goez-Gazi, Kendra J. Alfson, Abdul S. Yunus, Eric A. Toth, Gilad Ofek, Ricardo Carrion, Mark R. Prausnitz, Thomas R. Fuerst, Alexander K. Andrianov
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 1, p 16 (2022)
Ebolavirus (EBOV) infection in humans is a severe and often fatal disease, which demands effective interventional strategies for its prevention and treatment. The available vaccines, which are authorized under exceptional circumstances, use viral vec
Externí odkaz:
https://doaj.org/article/a885540978ff4542aea23a7fac2aa739
Publikováno v:
Molecules, Vol 27, Iss 21, p 7424 (2022)
The in vivo potency of polyphosphazene immunoadjuvants is inherently linked to the ability of these ionic macromolecules to assemble with antigenic proteins in aqueous solutions and form physiologically stable supramolecular complexes. Therefore, in-
Externí odkaz:
https://doaj.org/article/eccfe9bf944844bdaaaa8b261d2fb627
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1834 (2021)
Self-assembly of ionically charged small molecule drugs with water-soluble biodegradable polyelectrolytes into nano-scale complexes can potentially offer a novel and attractive approach to improving drug solubility and prolonging its half-life. Nanoa
Externí odkaz:
https://doaj.org/article/974a39141b1f4bfabaf287a1638f48df
Autor:
Bareera Qamar, Melani Solomon, Alexander Marin, Thomas R. Fuerst, Alexander K. Andrianov, Silvia Muro
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 249 (2021)
Achieving intracellular delivery of protein therapeutics within cells remains a significant challenge. Although custom formulations are available for some protein therapeutics, the development of non-toxic delivery systems that can incorporate a vari
Externí odkaz:
https://doaj.org/article/a647b9cadc994d55bfcf9c3e6fc770c3
Publikováno v:
Heliyon, Vol 2, Iss 4 (2016)
Water-soluble polyphosphazene polyacids, such as poly[di(carboxylatophenoxy)phosphazene] (PCPP), have been of significant interest due to their unique immunoadjuvant and vaccine delivery properties. We report that PCPP can spontaneously self-assemble
Externí odkaz:
https://doaj.org/article/ace57bd8da284232affb1f3be75d243c
Autor:
Harichandra D. Tagad, Jordan Brito, Alexander Marin, Christian Buckley, Haoyu Wang, Jingyu Sun, Svetlana A. Sukhishvili, Hongjun Wang, Alexander K. Andrianov
Publikováno v:
Biomacromolecules. 24:2278-2290
Autor:
Mingliang Lin, Alexander Marin, Beverly Ellis, Lisa M. Eubanks, Alexander K. Andrianov, Kim D. Janda
Publikováno v:
Molecular Pharmaceutics. 19:3358-3366
Cocaine is a highly addictive drug that has seen a steady uptrend causing severe health problems worldwide. Currently, there are no approved therapeutics for treating cocaine use disorder; hence, there is an urgent need to identify new medications. I