Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexander M. Rhyner"'
Autor:
Alexander M. Herman, Alexander M. Rhyner, W. Patrick Devine, Sean P. Marrelli, Benoit G. Bruneau, Joshua D. Wythe
Publikováno v:
Biology Open, Vol 7, Iss 3 (2018)
Canonical Notch signaling requires the presence of a membrane bound ligand and a corresponding transmembrane Notch receptor. Receptor engagement induces multiple proteolytic cleavage events culminating in the nuclear accumulation of the Notch intrace
Externí odkaz:
https://doaj.org/article/3ede507323064417bd724c3218b56e79
Autor:
Sunil K Verma, Vaibhav Deshmukh, Kaitlyn Thatcher, KarryAnne K Belanger, Alexander M Rhyner, Shu Meng, Richard Joshua Holcomb, Michael Bressan, James F Martin, John P Cooke, Joshua D Wythe, Steven G Widen, Joy Lincoln, Muge N Kuyumcu-Martinez
Publikováno v:
Nucleic acids research. 50(4)
Human genetic studies identified a strong association between loss of function mutations in RBFOX2 and hypoplastic left heart syndrome (HLHS). There are currently no Rbfox2 mouse models that recapitulate HLHS. Therefore, it is still unknown how RBFOX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dd2ff581b09fbfc707ec20c27be179
https://pubmed.ncbi.nlm.nih.gov/35137168
https://pubmed.ncbi.nlm.nih.gov/35137168
Autor:
Tara L. Rasmussen, Ryan S. Udan, Mary E. Dickinson, Ross A. Poché, Joshua D. Wythe, Monica D. Garcia, Alexander M. Rhyner, Rebecca Lee Yean Wong, Nanbing Li-Villarreal
The establishment of a functional circulatory system is required for post-implantation development during murine embryogenesis. Previous studies in loss of function mouse models have shown that FOXO1, a Forkhead family transcription factor, is requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1421c7d4bcedabc2db76264f75735d66
https://doi.org/10.1101/2021.09.02.458792
https://doi.org/10.1101/2021.09.02.458792
Autor:
Oscar E. Ruiz, Abiud Cantu Gutierrez, Alexander M. Rhyner, George T. Eisenhoffer, Manuel Cantu Gutierrez, Joshua D. Wythe
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000343 (2019)
PLoS Biology
PLoS Biology
The zebrafish Danio rerio is a powerful model system to study the genetics of development and disease. However, maintenance of zebrafish husbandry records is both time intensive and laborious, and a standardized way to manage and track the large amou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d7724053f1e9edd4659b8a3ebd019f
Autor:
Nadiya Khyzha, Alexander M. Rhyner, Jason E. Fish, Zhiqi Chen, Oscar E. Ruiz, Makon-Sébastien Njock, Lina Antounians, Alejandra Medina-Rivera, Joshua D. Wythe, Alexander M. Herman, Emilie Boudreau, George T. Eisenhoffer, Melvin Khor, Shawn Veitch, Manuel Cantu Gutierrez, Henry S. Cheng, Lan T.H. Dang, Michael D. Wilson
Publikováno v:
Development.
The transcriptional pathways activated downstream of vascular endothelial growth factor (VEGF) signaling during angiogenesis remain incompletely characterized. By assessing the signals responsible for induction of the Notch ligand delta-like 4 (DLL4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d318c369364b6e0ced00483c6f089c2
https://doi.org/10.1242/dev.146050
https://doi.org/10.1242/dev.146050
Autor:
Hui Yu, Joan P. Zape, Alexander M. Rhyner, Frank L. Bos, Joshua D. Wythe, Hugo Pinto, Mary E. Donohoe, Kelly M. Cautivo, Carlos Lizama, Ann C. Zovein, Christopher E. Schmitt, John S. Hawkins
Publikováno v:
Nature Communications
Changes in cell fate and identity are essential for endothelial-to-haematopoietic transition (EHT), an embryonic process that generates the first adult populations of haematopoietic stem cells (HSCs) from hemogenic endothelial cells. Dissecting EHT r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011822f8ff2c7fbf4953d207e1f43814
https://doi.org/10.1038/ncomms8739
https://doi.org/10.1038/ncomms8739
Autor:
Abiud Cantu Gutierrez, Manuel Cantu Gutierrez, Alexander M Rhyner, Oscar E Ruiz, George T Eisenhoffer, Joshua D Wythe
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000343 (2019)
The zebrafish Danio rerio is a powerful model system to study the genetics of development and disease. However, maintenance of zebrafish husbandry records is both time intensive and laborious, and a standardized way to manage and track the large amou
Externí odkaz:
https://doaj.org/article/81f17d17588c431fac22098eb2455dc4