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pro vyhledávání: '"Alexander M. Mørch"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The T-cell coreceptors CD4 and CD8 have well-characterized and essential roles in thymic development, but how they contribute to immune responses in the periphery is unclear. Coreceptors strengthen T-cell responses by many orders of magnitude – bey
Externí odkaz:
https://doaj.org/article/718d990dbd3f4b5ab090986fc4573a64
Autor:
Alexander M. Mørch, Falk Schneider
Publikováno v:
The Immune Synapse ISBN: 9781071631348
Activation of immune cells and formation of immunological synapses (IS) rely critically on the reorganization of the plasma membrane. These highly orchestrated processes are driven by diffusion and oligomerization dynamics, as well as by single molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2546c77498b9788ab49ebc5994e46079
https://doi.org/10.1007/978-1-0716-3135-5_5
https://doi.org/10.1007/978-1-0716-3135-5_5
Autor:
Alexander M. Mørch, Falk Schneider, Edward Jenkins, Ana Mafalda Santos, Scott E. Fraser, Simon J. Davis, Michael L. Dustin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(49)
The sensitivity of the αβ T-cell receptor (TCR) is enhanced by the coreceptors CD4 and CD8αβ, which are expressed primarily by cells of the helper and cytotoxic T-cell lineages, respectively. The coreceptors bind to major histocompatibility compl
Autor:
Adam J. Reid, Matthew K. Higgins, James H. Felce, Akihito Sakoguchi, Hisashi Arase, Michael L. Dustin, Thomas E. Harrison, Alexander M. Mørch
Publikováno v:
Nature
The Plasmodium species that cause malaria are obligate intracellular parasites, and disease symptoms occur when these parasites replicate in human blood. Despite the risk of immune detection, the parasite delivers proteins that bind to host receptors