Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Alexander M. Korolev"'
Autor:
Lakshay Malhotra, Punit Kaur, Valeria A. Litvinova, Mandeep Singh, Mukesh Kumar, Alexander S. Tikhomirov, Uddipan Das, Andrey E. Shchekotikhin, Alexander M. Korolev, Anzarul Haque, Abdul S. Ethayathulla
Publikováno v:
Biochimie. 182:152-165
The quest for effective anticancer therapeutics continues to be extensively pursued. Over the past century, several drugs have been developed, however, a majority of these drugs have a poor therapeutic index and increased toxicity profile. Hence, the
Publikováno v:
Pharmaceutical Chemistry Journal. 54:1263-1268
A new optimal synthetic scheme for new antibacterial compounds combining tris-(1-alkyindol-3-yl)methylium and 3-(indol-1-yl)maleimide in their structures was developed. The proposed method provided a significant increase in the product yield, reduced
Autor:
Alexey S Trenin, Elena P. Mirchink, S. N. Lavrenov, Elena B. Isakova, Alexey A. Panov, Alexander M. Korolev
Publikováno v:
The Journal of Antibiotics. 74:219-224
A series of new compounds—arylbis(indol-3-yl)methylium derivatives—were synthesized and their antimicrobial activity was evaluated. All the compounds turned out to be highly active, with MIC depending on their structure and the length of N-alkyl
Publikováno v:
Russian Journal of Organic Chemistry. 55:1847-1852
Previously unknown 2-(arylsulfanyl)-3-hydroxymaleimide and 2-(arylsulfanyl)-3-chloromaleimide derivatives have been synthesized, and several synthetic approaches to 2-(arylamino)-3-(arylsulfanyl)-maleimides have been tested. The reactivities of 2-chl
Autor:
Olga B. Bekker, Valery N. Danilenko, Oleg Y Saveljev, George V. Zatonsky, Alexander M. Korolev, Lyudmila N. Lysenkova, Andrey E. Shchekotikhin, Olga A. Omelchuk, Lyubov G. Dezhenkova, Alexander M. Scherbakov, D. A. Mavletova, Natalya E Grammatikova
Publikováno v:
Natural Product Research. 34:3073-3081
We describe the synthesis of epi-oligomycin A, a (33S)-diastereomer of the antibiotic oligomycin A. The structure of (33S)-oligomycin A was determined by elemental analysis, spectroscopic studies, including 1D and 2D NMR spectroscopy, and mass spectr
Autor:
Alexey A. Panov, Eugeny E. Bykov, Alexey S Trenin, S. N. Lavrenov, Alexander Y. Simonov, Alexander M. Korolev
Publikováno v:
MODERN SYNTHETIC METHODOLOGIES FOR CREATING DRUGS AND FUNCTIONAL MATERIALS (MOSM2020): PROCEEDINGS OF THE IV INTERNATIONAL CONFERENCE.
The difference in the reactivity of maleimide derivatives is explained by the method of calculating partial charges on carbon atoms of 3-substituted-4-bromomaleimides, as well as by 3D molecular modeling. The influence of various substituents on the
Autor:
Daria V. Andreeva, Alexander S. Tikhomirov, Alexander M. Korolev, Andrey E. Shchekotikhin, Yuri B. Sinkevich, Yury N. Luzikov
Publikováno v:
Chemistry of Heterocyclic Compounds. 54:612-617
Methods have been developed for the synthesis of anthra[2,3-b]thiophene-3(2)-carboxylic acids and their derivatives through modifications of 4,11-dibutoxy-3-methylanthra[2,3-b]thiophene-5,10-dione. A scheme involving methyl group transformations was
Autor:
Natalia E. Grammatikova, Olga B. Bekker, Nikita M. Belov, Lyubov G. Dezhenkova, Valery N. Danilenko, Olga A. Omelchuk, Lyudmila N. Lysenkova, Alexander M. Korolev, Andrey E. Shchekotikhin, Vladimir B. Tsvetkov
Publikováno v:
Macroheterocycles. 11:181-192
Autor:
Alexander M. Korolev, Valery N. Danilenko, Natalia E. Grammatikova, Olga B. Bekker, Andrey E. Shchekotikhin, Lyudmila N. Lysenkova, Nikita M. Belov, Olga A. Omelchuk, Lyubov G. Dezhenkova
Publikováno v:
Macroheterocycles. 11:322-328
Autor:
Yuri B. Sinkevich, Valeriya A. Litvinova, Andrey E. Shchekotikhin, Alexander S. Tikhomirov, Yury N. Luzikov, Alexander M. Korolev
Publikováno v:
Chemistry of Heterocyclic Compounds. 53:1072-1079
3-carboxylate by using vicarious substitution of hydrogen, followed by intramolecular reductive heterocyclization. Some chemical properties of the target compound were characterized. As observed for the first time in the series of linear hetaryl-fuse