Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Alexander M. Klibanov"'
Autor:
Tamires Cunha Almeida, Maria Betânia de Freitas Marques, Cibele Rodrigues Toledo, Mariana Campos Da Paz, Wagner da Nova Mussel, Gisele Rodrigues da Silva, Alexander M. Klibanov, Glenda Nicioli da Silva, Harley Da Silva Tavares, Armando Silva-Cunha, Fernanda Barçante Perasoli, Priscilla Oliveira Gil, Paulo Afonso Granjeiro, Juliana Texeira de Magalhães, Jéssica Ferreira Cardoso
Publikováno v:
International journal of biological macromolecules. 169
Vancomycin-loaded N,N-dodecyl,methyl-polyethylenimine nanoparticles coated with hyaluronic acid (VCM-DMPEI nanoparticles/HA) were synthesized as an adjuvant for the treatment of bacterial endophthalmitis. The nanoparticles were formulated by experime
Autor:
Ashish Tandon, Ajay Sharma, Jason T Rodier, Alexander M Klibanov, Frank G Rieger, Rajiv R Mohan
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66434 (2013)
This study examined the effects of BMP7 gene transfer on corneal wound healing and fibrosis inhibition in vivo using a rabbit model. Corneal haze in rabbits was produced with the excimer laser performing -9 diopters photorefractive keratectomy. BMP7
Externí odkaz:
https://doaj.org/article/868ca0f35ca4470b9e235b64308db20e
Autor:
Alexander M. Klibanov, Steven P. Schwendeman, Malcolm R. Brandon, Robert Langer, Michael Cardamone
This chapter discusses the concepts of biochemistry, polymer science, and microencapsulation to examines the complexity of formulating these dosage forms; particular emphasis is placed on the strategies and experimental methods used to handle the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35805692b0c026916220bf58437d7caf
https://doi.org/10.1201/9781003067542-1
https://doi.org/10.1201/9781003067542-1
Autor:
Alisha K. Weight, Alyssa M. Larson, Amanda Bonificio, Kevin Love, Alexander M. Klibanov, Charles R. Wescott
Publikováno v:
Journal of Pharmaceutical Sciences. 106:1211-1217
The viscosity of concentrated aqueous solutions of 3 clinical monoclonal antibodies (mAbs), Erbitux®, Herceptin®, and Rituxan®, has been reduced up to over 10-fold by adding certain bulky polar additives instead of saline at isotonic levels. Becau
Autor:
Awanish Kumar, Alexander M. Klibanov
Publikováno v:
Springer US
The problem of gelation of concentrated protein solutions, which poses challenges for both downstream protein processing and liquid formulations of pharmaceutical proteins, is addressed herein by employing previously discovered viscosity-lowering bul
Autor:
Alexander M. Klibanov
Publikováno v:
Biotechnology & Biological Frontiers ISBN: 9780429050329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a529f5e1a15fcf3a68fe8bacd44475b
https://doi.org/10.4324/9780429050329-19
https://doi.org/10.4324/9780429050329-19
Autor:
Christopher Weikart, Steven P. Martin, Adam P. Breeland, Brian R. Maurer, Alexander M. Klibanov, Taha Ahmad
Publikováno v:
Slas Technology
SiO2 Medical Products, Inc. (SiO) has developed a proprietary technology that greatly enhances protein recoveries and reduces extractables from commercial microplates used for bioanalytical assays and storage of biologics. SiO technology is based on
Publikováno v:
Chen
Purpose: Previously, polymer-attached zanamivir had been found to inhibit influenza A viruses in vitro far better than did small-molecule zanamivir (1) itself. The aim of this study was to identify in vitro—using the plaque reduction assay—a high
Publikováno v:
PMC
By attaching multiple copies of the influenza M2 ion channel inhibitors amantadine (1) and rimantadine (2) to polymeric chains, we endeavored to recover their potency in inhibiting drug-resistant influenza viruses. Depending on loading densities, as
Autor:
Alexander M. Klibanov, Alyssa M. Larson, Barbara Abrams, Carl V. Hanson, Nigel K.H. Slater, Mary Kate Morris, Stephen E. Gerrard
Publikováno v:
Biotechnology and Bioengineering. 110:2058-2062
The infectivity of high-titer, cell-free HIV in culture media and human milk is rapidly reduced upon exposure to polyethylene slides painted with the linear hydrophobic polycation N,N-dodecyl,methyl-polyethylenimine (DMPEI). Accompanying viral p24 pr