Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexander M. Harmon"'
Autor:
Atanas Koulov, Maloney Kevin, Wei Liu, Alexander M. Harmon, Hanns-Christian Mahler, Dilbir S. Bindra, Ping Y Yeh, Kapil Gupta, Sandeep Yadav, Vincent Corvari, R. Matthew Fesinmeyer, Michael T. Jones, John Wang, Satish K. Singh, Kenneth D Hinds
Publikováno v:
Pharmaceutical Research. 35
Polysorbates are commonly added to protein formulations and serve an important function as stabilizers. This paper reviews recent literature detailing some of the issues seen with the use of polysorbate 80 and polysorbate 20 in protein formulations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b78aa6314c10e502e9b055bf4c81f5
https://doi.org/10.1007/s11095-018-2430-5
https://doi.org/10.1007/s11095-018-2430-5
Publikováno v:
Journal of Controlled Release. 153:233-239
Amphiphilic macromolecules (AM) were electrostatically complexed with a 1:1 ratio of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) to form AM–lipid complexes with drug delivery application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627686b72b4dcd6aece330be4cebf547
https://doi.org/10.1016/j.jconrel.2011.04.004
https://doi.org/10.1016/j.jconrel.2011.04.004
Autor:
Alexander M. Harmon, Leora M. Nusblat, Kathryn E. Uhrich, Carolyn L. Waite, Sarah M. Sparks, Charles M. Roth
Publikováno v:
Macromolecular Bioscience. 11:1192-1200
New materials that can bind and deliver oligonucleotides such as short interfering RNA (siRNA) without toxicity are greatly needed to fulfill the promise of therapeutic gene silencing. Amphiphilic macromolecules (AMs) were functionalized with linear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692a9b2aa0fea7d7ac831c58cd883de4
https://doi.org/10.1002/mabi.201100064
https://doi.org/10.1002/mabi.201100064
Autor:
David E. Orban, Bahar Demirdirek, Leilani S. del Rosario, Alexander M. Harmon, Kathryn E. Uhrich
Publikováno v:
Macromolecular Bioscience. 10:415-423
Amphiphilic macromolecules (AMs) have unique branched hydrophobic domains attached to linear PEG chains. AMs self-assemble in aqueous solution to form micelles that are hydrolytically stable in physiological conditions (37 degrees C, pH 7.4) over 4 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc6b9d377af503801b6fe6b07608639d
https://doi.org/10.1002/mabi.200900335
https://doi.org/10.1002/mabi.200900335
Autor:
Kathryn E. Uhrich, Alexander M. Harmon
Publikováno v:
Journal of Bioactive and Compatible Polymers. 24:185-197
Amphiphilic star-like macromolecules and amphiphilic scorpion-like macromolecules are polymeric micelles capable of water-solubilizing hydrophobic molecules for intravenous injection. In this work, four different amphiphilic macromolecules (M12P5, M6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf1ac0c39ca5c4476569c7ada86c556
https://doi.org/10.1177/0883911509101557
https://doi.org/10.1177/0883911509101557
Publikováno v:
Biomaterials. 32(36)
Fibrin Pad is a hemostatic pad designed to control surgical-related bleeding. It consists of a fully absorbable composite matrix scaffold coated with human-derived active biologics that immediately form a fibrin clot upon contact with targeted bleedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7a7ce8ab5964bbaad3e6b7ef619a1b
https://pubmed.ncbi.nlm.nih.gov/21944828
https://pubmed.ncbi.nlm.nih.gov/21944828
Autor:
Alexander M. Harmon, Evan Mintzer, Nasim Tishbi, Danielle Lent, Melissa H. Lash, Kathryn E. Uhrich
Surfactant amphiphilic macromolecules (AMs) were complexed with a 1:1 ratio of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), either by a coevaporation (CE) or postaddition (PA) method, to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504463d3d1ad1d586753df4e8a0d5163
https://europepmc.org/articles/PMC3566872/
https://europepmc.org/articles/PMC3566872/
Autor:
Sarah M, Sparks, Carolyn L, Waite, Alexander M, Harmon, Leora M, Nusblat, Charles M, Roth, Kathryn E, Uhrich
Publikováno v:
Macromolecular bioscience. 11(9)
New materials that can bind and deliver oligonucleotides such as short interfering RNA (siRNA) without toxicity are greatly needed to fulfill the promise of therapeutic gene silencing. Amphiphilic macromolecules (AMs) were functionalized with linear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ffbe982f9c6b6b32f0089f5e94e987a
https://pubmed.ncbi.nlm.nih.gov/21793212
https://pubmed.ncbi.nlm.nih.gov/21793212
Autor:
Raymond D. Lund, Anthony J. Kihm, Yves Sauve, Anna Gosiewska, Bin Lu, Darin J. Messina, Sanjay Mistry, Feng-Yi Chin, Ian Ross Harris, Toby Holmes, Shaomei Wang, S.V. Girman, Alexander M. Harmon
Publikováno v:
Stem cells (Dayton, Ohio). 25(3)
Progressive photoreceptor degeneration resulting from genetic and other factors is a leading and largely untreatable cause of blindness worldwide. The object of this study was to find a cell type that is effective in slowing the progress of such dege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a4df5aaf9614ec472802a2c65d2922
https://pubmed.ncbi.nlm.nih.gov/17053209
https://pubmed.ncbi.nlm.nih.gov/17053209
Autor:
Alexander M. Harmon, Melissa H. Lash, Nasim Tishbi, Danielle Lent, Evan A. Mintzer, Kathryn E. Uhrich
Publikováno v:
Langmuir; Aug2011, Vol. 27 Issue 15, p9131-9138, 8p