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pro vyhledávání: '"Alexander M. Gorbushin"'
Autor:
Alexander M. Gorbushin
Publikováno v:
Fish & Shellfish Immunology. 120:11-14
Peptidoglycan Recognition Proteins (PGRPs) are a diverse group of proteins involved in innate immunity. In particular, PGRPs have been shown to participate in immune pattern recognition in various mollusks. However, they have not been described in Ca
Publikováno v:
Journal of experimental zoology. Part B, Molecular and developmental evolutionREFERENCES. 340(1)
Organization and functioning of immune system remain unevenly studied in different taxa of lophotrochozoan animals. We analyzed transcriptomic data on coelomocytes of the lugworm Arenicola marina (Linnaeus, 1758; Annelida, Polychaeta) to gain insight
Autor:
Alexander M. Gorbushin
Publikováno v:
Fishshellfish immunology. 106
The transcriptome of the caenogastropod mollusk Littorina littorea was scanned for the presence of sequences encoding Toll-like receptors (TLRs) and corresponding proteins involved in downstream TLR signaling pathway. In the transcriptomic snapshots
Autor:
Alexander M. Gorbushin
Publikováno v:
Developmental & Comparative Immunology. 84:250-263
The evolution of complement system in invertebrates is poorly investigated. While the repertoire of complement genes in several Ecdysozoa lineages is found substantially different from that of Deuterostomia, the composition and function of the comple
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 53:470-479
A comparative immunological survey of cytotoxic properties of whole and cell-free haemolymph (plasma) was performed on four species of marine molluscs. Diverse target cells were used: auto- and heterologous mollusc haemocytes, starfish Asterias ruben
Autor:
Alexander M. Gorbushin
Publikováno v:
Developmental and comparative immunology. 94
A plethora of non-overlapping immune molecular mechanisms in metazoans is the most puzzling issue in comparative immunobiology. No valid evolutionary retrospective on these mechanisms has been developed. In this study, we aimed to reveal the origin a
Publikováno v:
Developmental & Comparative Immunology. 48:210-220
The common periwinkle Littorina littorea was introduced in the list of models for comparative immunobiology as a representative of phylogenetically important taxon Caenogastropoda. Using Illumina sequencing technology, we de novo assembled the transc
Autor:
Alexander M. Gorbushin
Publikováno v:
Fish & Shellfish Immunology. 54:254-256
The MACPF domain-containing proteins potentially able to build a transmembrane pore structure are found in the transcriptome of a common periwinkle kidney loaded with trematode rediae. Two homologs of mammalian Macrophage expressed gene 1 (Mpeg1), Ll
Publikováno v:
Fish & Shellfish Immunology. 39:432-438
All semelparous short-lived gastropods studied so far for the experimental transplantation of trematode parthenitae, from one specific host to another, showed more or less successful acceptance of implanted parasites. We implanted echinostomatid redi
Autor:
Alexander M. Gorbushin
Publikováno v:
Developmental & Comparative Immunology. 101:103465
The caenogastropod mollusk Littorina littorea is a promising experimental model for comparative studies on host/parasite immune conflict. Several different digenean parasites use L. littorea as the first intermediate host, overcoming snail immune rea