Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Alexander M. Firsov"'
Autor:
Roman S. Kirsanov, Ljudmila S. Khailova, Tatyana I. Rokitskaya, Konstantin G. Lyamzaev, Alisa A. Panteleeva, Pavel A. Nazarov, Alexander M. Firsov, Iliuza R. Iaubasarova, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11551-11561 (2024)
Externí odkaz:
https://doaj.org/article/a4be645a79fa4de490a45a3780dca471
Autor:
Pavel A. Nazarov, Vladislav S. Maximov, Alexander M. Firsov, Marina V. Karakozova, Veronika Panfilova, Elena A. Kotova, Maxim V. Skulachev, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6137 (2024)
Mitochondria-targeted antioxidants (MTAs) have been studied quite intensively in recent years as potential therapeutic agents and vectors for the delivery of other active substances to mitochondria and bacteria. Their most studied representatives are
Externí odkaz:
https://doaj.org/article/60d327de2eb64c31baf99c99657766e1
Autor:
Tatyana I. Rokitskaya, Alexander M. Arutyunyan, Ljudmila S. Khailova, Alisa D. Kataeva, Alexander M. Firsov, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16203 (2022)
Usnic acid (UA), a unique lichen metabolite, is a protonophoric uncoupler of oxidative phosphorylation, widely known as a weight-loss dietary supplement. In contrast to conventional proton-shuttling mitochondrial uncouplers, UA was found to carry pro
Externí odkaz:
https://doaj.org/article/f5947b57755e45d495a0d0a1646a4dce
Autor:
Rita V. Chertkova, Alexander M. Firsov, Nadezda A. Brazhe, Evelina I. Nikelshparg, Zhanna V. Bochkova, Tatyana V. Bryantseva, Marina A. Semenova, Adil A. Baizhumanov, Elena A. Kotova, Mikhail P. Kirpichnikov, Georgy V. Maksimov, Yuriy N. Antonenko, Dmitry A. Dolgikh
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 665 (2022)
A key event in the cytochrome c-dependent apoptotic pathway is the permeabilization of the outer mitochondrial membrane, resulting in the release of various apoptogenic factors, including cytochrome c, into the cytosol. It is believed that the permea
Externí odkaz:
https://doaj.org/article/c9c20935cd1246f7b0ef1028804b5386
Autor:
Viktoriia E. Baksheeva, Ekaterina L. Nemashkalova, Alexander M. Firsov, Arthur O. Zalevsky, Vasily I. Vladimirov, Natalia K. Tikhomirova, Pavel P. Philippov, Andrey A. Zamyatnin, Dmitry V. Zinchenko, Yuri N. Antonenko, Sergey E. Permyakov, Evgeni Yu. Zernii
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 164 (2020)
Neuronal calcium sensors are a family of N-terminally myristoylated membrane-binding proteins possessing a different intracellular localization and thereby targeting unique signaling partner(s). Apart from the myristoyl group, the membrane attachment
Externí odkaz:
https://doaj.org/article/26254274f5cb40a38891f75eef47860b
Publikováno v:
Antioxidants, Vol 8, Iss 6, p 194 (2019)
It is generally considered that reactive oxygen species (ROS) are involved in the development of numerous pathologies. The level of ROS can be altered via the uncoupling of oxidative phosphorylation by using protonophores causing mitochondrial membra
Externí odkaz:
https://doaj.org/article/2118f00f330449d6ab143d9b863e19db
Autor:
Alexander M. Firsov, Ljudmila S. Khailova, Tatyana I. Rokitskaya, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Biochemistry (Moscow). 87:812-822
Pyrrolomycins C (Pyr_C) and D (Pyr_D) are antibiotics produced by Actinosporangium and Streptomyces. The mechanism of their antimicrobial activity consists in depolarization of bacterial membrane, leading to the suppression of bacterial bioenergetics
Autor:
Alexander M. Firsov, Juergen Pfeffermann, Anton S. Benditkis, Tatyana I. Rokitskaya, Anton S. Kozlov, Elena A. Kotova, Alexander A. Krasnovsky, Peter Pohl, Yuri N. Antonenko
Publikováno v:
Journal of photochemistry and photobiology. B, Biology. 239
The chase toward endowing chemical compounds with machine-like functions mimicking those of biological molecular machineries has yielded a variety of artificial molecular motors (AMMs). Pharmaceutical applications of photoexcited monomolecular unidir
Autor:
Vladimir S. Krasnov, Roman S. Kirsanov, Ljudmila S. Khailova, Lyudmila B. Popova, Konstantin G. Lyamzaev, Alexander M. Firsov, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Archives of biochemistry and biophysics. 728
An impressive body of evidence has been accumulated now on sound beneficial effects of mitochondrial uncouplers in struggling with the most dangerous pathologies such as cancer, infective diseases, neurodegeneration and obesity. To increase their eff
Autor:
Mikhail P. Kirpichnikov, Rita V. Chertkova, Yuri N. Antonenko, I. D. Gusev, Alexander M. Firsov, Dmitry A. Dolgikh, Elena A. Kotova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 46:1162-1171
Here, we studied the interaction of Cys-substituted (G56C) cytochrome c labeled with sulfocyanin-3 fluorescent dye (fCyt) with artificial and natural lipid membranes by using fluorescence correlation spectroscopy (FCS). Compared to mitochondria, mito