Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexander M. Cummings"'
Autor:
Laura K. Donohue, Gene H Thiede, Fiona P. Ukken, C. Dustin Rubinstein, Scott J. Gratz, Alexander M. Cummings, Kate M. O'Connor-Giles
Publikováno v:
Genetics
We and others recently demonstrated that the readily programmable CRISPR/Cas9 system can be used to edit the Drosophila genome. However, most applications to date have relied on aberrant DNA repair to stochastically generate frameshifting indels and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b9d3441e027ef32b0c779acb1fdc73
http://europepmc.org/articles/PMC3982687
http://europepmc.org/articles/PMC3982687
Autor:
Scott J. Gratz, Danielle C. Hamm, Jill Wildonger, Alexander M. Cummings, Melissa M. Harrison, Jennifer N. Nguyen, Kate M. O'Connor-Giles, Laura K. Donohue
Publikováno v:
Genetics
We have adapted a bacterial CRISPR RNA/Cas9 system to precisely engineer the Drosophila genome and report that Cas9-mediated genomic modifications are efficiently transmitted through the germline. This RNA-guided Cas9 system can be rapidly programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf804517bfddd454c892887f2e47b86
https://pubmed.ncbi.nlm.nih.gov/23709638
https://pubmed.ncbi.nlm.nih.gov/23709638
Autor:
Richard R. Geske, Joseph J. Bruckner, Laura K. Donohue, Samantha E. Galindo, Alexander M. Cummings, Scott J. Gratz, Jessica K. Slind, Kate M. O'Connor-Giles
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(48)
Neuronal communication depends on the precisely orchestrated release of neurotransmitter at specialized sites called active zones (AZs). A small number of scaffolding and cytoskeletal proteins comprising the cytomatrix of the active zone (CAZ) are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276502099be5d50a327935f555b206dd
https://pubmed.ncbi.nlm.nih.gov/23197698
https://pubmed.ncbi.nlm.nih.gov/23197698